The article is devoted to the development of requirements for software products and services that implement the technology of medical computer-aided design, as well as designed to support the development and implementation of medical computer-aided design systems as a class of computer systems. The review of achievements in the field of computer-aided design for solving medical problems is given. To ensure consistency in the development of medical CAD infrastructure, the Top-Down approach is used. The work describes the upper level of the architecture of the information infrastructure and the typical business process of using its elements in the development and implementation of medical CAD: as an example, is selected the Medical computer-aided design system of bioprinting and transplantation of the human limbs. General requirements for programs and components, and key functional requirements for medical CAD systems are developed. Methods for verifying compliance with the stated requirements are described. The results obtained allow to move on to the development of separate elements of the medical CAD infrastructure and their further integration into unified information environment.