“…In the scope of Machine Learning-based (ML) techniques, the major part of recent studies use CCTA characteristics as reference [3,5,21,28,34,39,45,52], but most of them also were evaluated with a reduced number of patients and arteries [5,21,28,33,34,42,50]. These researches use geometrical lesion data [3,21,28,39,42,45,52], clinical risk scores [39] and anatomical descriptors [34].…”