Clathrochelate Complexes Containing Axial Cymantrene and Tromancenium Moieties

Abstract

New clathrochelate complexes of manganese, iron and cobalt containing peripheral organometallic manganese moieties cymantrene or tromancenium were synthesized via self‐assembly from di/tri‐topic dioximes, metal templates and cymantrene/tromancenium boronic acid pinacol esters. These air‐stable, highly colored, oligometallic complexes are composed of various combinations of MnIFeIIMnI, MnICoIIMnI, MnIMnIIMnIIMnI and MnICoIICoIIMnI metal assemblies with corresponding complicated magnetic and electrochemical properties. Full spectroscopic and structural characterization by 1H/11B/13C NMR, HRMS, IR, UV‐vis, single crystal XRD and CV (cyclic voltammetry) is provided. Tetrametallic complexes containing tromanceniumyl substituents with two CoII or MnII central metals exhibit promising anticancer properties against different tumor cell lines.

Preparation, X-ray Characterization, and Reactivity of the Rod-like and Angular Germanium- and Titanium(IV)-Capped Iron(II) Bis-Clathrochelates and Their Mono- and Bis-Capped (Semi)clathrochelate Precursors

“…Tris-α-diiminate d-metal clathrochelates are known , to be the chemically robust coordination compounds possessing unusual chemical, optical, and redox properties. − They have been earlier proposed as prospective topological (pro)­drugs, − optical probes, − molecular magnetic devices and materials, − and homo- and heterogeneous catalysts, − including those for efficient hydrogen and syngas production . Very recently, a 3D-shaped iron­(II) clathrochelate with a functionalizing terminal biorelevant group is reported to bind the macromolecules of unfolded proteins in the endoplasmic reticulum of cancer cells.…”