Clearance of yellow tattoo ink with a novel 532‐nm picosecond laser

Alabdulrazzaq, Hamad; Brauer, Jeremy A.; Bae, Yoon-Soo Cindy; Geronemus, Roy G.

doi:10.1002/lsm.22354

Cited by 70 publications

(71 citation statements)

References 10 publications

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“…In a comparative study on the use of 1064-nm picosecond-domain lasers for the removal of black ink tattoos [15], 90-100 % clearance rates were observed in 2/16 patients treated during four sessions with the picosecond-domain laser compared to none of the patients treated with the nanosecond laser [15]. Others reported that one to five treatments with the frequencydoubled 1064/532-nm picosecond-domain laser cleared 90-100 % of yellow ink tattoos in four of the six patients (67 %) [19]. A second trial [17] with the frequency-doubled laser at the same wavelength reported an average 91.6 ± 5.4 % clearance of black pigment after up to seven sessions.…”

Section: -100 % Clearancementioning

confidence: 82%

“…Seven trials explored the use of either 1064 nm (Nd:YAG) [15], 755 nm [16,18,20], 795 nm [13], 758 nm [14], or frequency-doubled 1064/532 nm [17] lasers for the treatment of mainly black and blue tattoos. One of the trials explored the use of frequency-doubled 1064/532-nm lasers for the treatment of yellow tattoos [19]. One trial [15] used a laser with a pulse duration of 35 ps, while the rest of the trials used lasers with pulse durations of 350-900 ps.…”

Section: Resultsmentioning

confidence: 99%

“…Eight studies fulfilled the eligibility criteria, including two non-randomized controlled trials in animal models [13,14] and clinical studies with 160 participants bearing 182 tattoos. The clinical studies included one non-randomized controlled trial [15], two noncontrolled prospective trials [16,17], two case series [18,19], and one retrospective case-control study that only investigated side effects [20]. The trials' characteristics are detailed in Tables 1 and 2.…”

Section: Resultsmentioning

confidence: 99%

“…One trial [19] treated six yellow tattoos with up to 10 sessions at 6-8-week intervals between them. They found that six of the six (100 %) tattoos had over 75 % clearance of yellow ink.…”

Section: Human Trialsmentioning

confidence: 99%

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Picosecond lasers for tattoo removal: a systematic review

et al. 2016

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Given that the pigment particles in tattoos have a relaxation time of <10 ns, picosecond lasers would be expected to be more effective than nanosecond lasers in tattoo removal. To systematically review the evidence regarding the effectiveness and safety of picosecond lasers for tattoo removal, Pubmed, Cochrane Central Register of Controlled Trials (CENTRAL), ClinicalTrials.gov, and reference lists were searched for relevant trials. The primary outcome was >70 % clearance of tattoo pigment. Secondary outcomes were 90-100 % clearance of tattoo pigment, number of laser sessions required, and adverse effects. Eight trials were included, six with human participants (160 participants) and 2 with animal models. Seven of the eight trials explored the usage of either 755, 758, 795, 1064, or 1064/532-nm picosecond lasers for black and blue ink tattoos. In the human trials, 69-100 % of tattoos showed over 70 % clearance of pigment after 1-10 laser treatments. Reported side effects included pain, hyperpigmentation and hypopigmentation, blister formation and transient erythema, edema, and pinpoint bleeding. Included articles varied in type of laser investigated, mostly non-comparative studies and with a medium to high risk of bias. There is sparse evidence that picosecond lasers are more effective than their nanosecond counterparts for mainly black and blue ink tattoo removal, with minor side effects.

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Section: -100 % Clearancementioning

confidence: 82%

Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

“…One trial [19] treated six yellow tattoos with up to 10 sessions at 6-8-week intervals between them. They found that six of the six (100 %) tattoos had over 75 % clearance of yellow ink.…”

Section: Human Trialsmentioning

confidence: 99%

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Picosecond lasers for tattoo removal: a systematic review

et al. 2016

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“…Генерирование оптических гармоник, в свою очередь, необходимо для получения излучения в спектре, отличном от излучения накачки. Например, вторая гармоника Nd:YAG лазера имеет длину волны 532 нм и широко используется в спектроскопии, медицине, голографии, а также при создании стандартов частоты [1]. Стабильные по частоте лазеры широко используются не только в научных исследованиях, но и в технике как эталонные источники света для интерферометрических измерений длины.…”

Section: Introductionunclassified

514.5…515 nm wavelength emission for molecular iodine spectroscopy purposes

Skvortsov¹,

Vіshnyakov²

2015

Transaction of Scientific Papers of the NSTU

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В статье рассмотрено современное состояние проблем лазерной спектроскопии, в том числе использование паров молекулярного йода для целей построения стандартов ча-стоты. Разработан генератор второй оптической гармоники от перестраиваемого воло-конного иттербиевого лазера на основе внешнего резонатора с кристаллом LBO (LiB3O5 -триборат лития) для последующего использования в экспериментах по спек-троскопии молекулярного йода. Особенностью собранного генератора второй оптиче-ской гармоники является использование перестраиваемого волоконного иттербиевого лазера с распределенной обратной связью. Перестройка по длине волны осуществля-лась в диапазоне 1029…1030 нм посредством изменения температуры резонатора лазе-ра. В основе рассматриваемого генератора второй гармоники лежит двухзеркальный ре-зонатор и кристалл LBO, расположенный в перетяжке резонатора удвоителя. Для целей стабилизации лазерного излучения использовалась система автоподстройки частоты (АПЧ). Для повышения стабильности частоты лазера использовался эталон Фабри-Перо. Для стабилизации частоты удвоителя была использована схема Паунда-Дривера-Холла. В ходе экспериментов были измерены шумовые характеристики излучения вто-рой гармоники. Чтобы учесть вклад, вносимый самим фотоприемником, был измерен спектр шумов используемого фотоприемника. Полученные результаты сравнивались с шумовыми характеристиками, полученными от лампы накаливания с тем же уровнем засветки. Построен график зависимости шумовых компонент от частоты. Исследована зависимость выходной мощности излучения второй гармоники от длины волны излуче-ния в диапазоне 514.5…515 нм. Построен график зависимости величины выходной мощности второй гармоники от длины волны излучения. В результате проделанной ра-боты получено до 13 мВт излучения во второй гармонике с возможностью перестройки длины волны генератора.* Статья получена 17 февраля 2015 г.

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A novel dual‐wavelength, Nd:YAG, picosecond‐domain laser safely and effectively removes multicolor tattoos

et al. 2015

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Background and ObjectivesAlthough nanosecond‐domain lasers have been the mainstay of laser tattoo removal for decades, recent disruptive innovations in laser design have introduced a new class of commercial Q‐switched lasers that generate picosecond‐domain pulses.StudyA picosecond‐domain, Nd:YAG laser with a KTP frequency‐doubling crystal was used to treat 31 decorative tattoos in 21 subjects. Safety and effectiveness were determined by blinded evaluation of digital images in this prospective clinical study.ResultsThe average clearance overall as evaluated by blinded observers evaluating randomized digital photographs was 79 ± 0.9% (mean ± sem) after an average of 6.5 treatments. Of the 31 tattoos completing treatment, 6 had evidence of mild hyper‐ or hypo‐pigmentation by evaluation of photographs.ConclusionThe 350 picosecond, 532 nm, and 450 picosecond 1,064 nm Nd:YAG laser is safe and effective for removing decorative tattoos. Lasers Surg. Med. 47:542–548, 2015. © 2015 The Authors. Lasers in Surgery and Medicine Published by Wiley Periodicals, Inc.

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Clearance of yellow tattoo ink with a novel 532‐nm picosecond laser

Cited by 70 publications

References 10 publications

Picosecond lasers for tattoo removal: a systematic review

Picosecond lasers for tattoo removal: a systematic review

514.5…515 nm wavelength emission for molecular iodine spectroscopy purposes

A novel dual‐wavelength, Nd:YAG, picosecond‐domain laser safely and effectively removes multicolor tattoos

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