Cleavage stage versus blastocyst stage embryo transfer in assisted reproductive technology

Glujovsky, Demián; Blake, Deborah; Bardach, Ariel; Farquhar, Cindy

doi:10.1002/14651858.cd002118.pub4

Cited by 281 publications

(314 citation statements)

References 71 publications

Supporting

Mentioning

298

Contrasting

Unclassified

Order By: Relevance

“…it has previously been reported that culture to the blastocyst stage (day 5) in women with good-quality embryos may facilitate embryo selection, reduce aneuploidy embryos 16 and improve live birth rates 17 . rijnders 18 and peramo 19 were the first to report an association between the incidence of mZT and blastocyst transfer.…”

Section: Length Of Culturementioning

confidence: 99%

High incidence of monozygotic twinning in infertility treatment

Sobek¹,

Procházka²,

Klásková³

et al. 2016

Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub

View full text Add to dashboard Cite

Background. Monozygotic twinning is associated with increased perinatal morbidity and mortality. There is evidence that the number of monozygotic twins increases after assisted reproductive techniques. Methods. We searched PUBMED, MEDLINE, and Scopus from 1987 to 2015 for studies analyzing the incidence and possible etiology of monozygotic twinning in infertility patients and critically reviewed the current state of knowledge. Results and Conclusions. Monozygotic twinning is a rare in natural conception but occurs around twice the normal rate after assisted reproduction. Factors associated with this phenomenon remain speculative, though there is some evidence that micromanipulation techniques, prolonged culture, and genetics are involved. In view of the possible complications, adequate pre-conception counselling is advocated.

show abstract

Section: Length Of Culturementioning

confidence: 99%

High incidence of monozygotic twinning in infertility treatment

Sobek¹,

Procházka²,

Klásková³

et al. 2016

Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub

View full text Add to dashboard Cite

show abstract

“…One of the strategies that have been suggested to overcome the detrimental eff ect of advanced endometrial maturation is to enable endometrial recovery before transfer. Numerous studies investigated the benefi t of day 5 compared to day 3 embryo transfer (ET) [35][36][37] ; increased probability of pregnancy with day 5 ET was recorded in 2 independent trials 36,38 . In other words, a higher rate of early pregnancy loss was recorded after day 3 single ET as compared with day 5 single blastocyst transfer in GnRH antagonist stimulated IVF cycles.…”

Section: Prevention Of Preovulatory Progesterone Elevationmentioning

confidence: 99%

Current Preventive Strategies for Preovulatory Progesterone Elevation During Ovarian Stimulation for in Vitro Fertilization

Ejubović

Kasum

Stanić

et al. 2016

acc

View full text Add to dashboard Cite

SUMMARY -Th e purpose of this review is to present contemporary measures for preventing the increase in preovulatory progesterone (P) and its adverse eff ects on ovarian stimulation in in vitro fertilization (IVF). For the last 20 years, the increase of preovulatory P has been a topic of numerous discussions because its role is not fully understood in terms of its impact on pregnancy outcome after IVF. Some studies failed to establish a connection between the preovulatory P increase and successful IVF outcome regardless of the level of P, while, conversely, most other studies have reported on adverse eff ects of elevated P concentrations. Current strategies to prevent the increase in preovulatory P include an individualized approach with the use of mild stimulation protocols and early application of human chorionic gonadotropin for ovulation induction among good responders, delay in the transfer of fresh embryos from 3 rd to 5 th day, and cryopreservation of all embryos with the thawed embryo transfer in the natural cycle. Nevertheless, further studies are needed to confi rm the current preventive methods or enable the application of new strategies in order to lower or eliminate the detrimental eff ects of preovulatory P rise during ovarian stimulation in IVF.

show abstract

“…Future RCTs should report miscarriage, live birth and cumulative live birth rates to facilitate well-informed decisions on the best treatment option available. (Glujovsky 2012) • Post-embryo transfer interventions for IVF and ICSI patients: there is insufficient evidence to support a certain amount of time for women to remain recumbent following embryo transfer, or to support the use of fibrin sealants.There is limited evidence to support the use of mechanical closure of the cervical canal following embryo transfer. Further well-designed studies are required.…”

Section: No Conclusion Possible Due To Lack Of Evidencementioning

confidence: 99%