Cleft lip/palate‐oligodontia‐syndactyly‐hair alterations, a new syndrome: Review of the conditions combining ecodermal dysplasia and cleft lip/palate

Abstract

We report on a noninbred girl with cleft lip and palate, complete absence of deciduous teeth, hypodontia of permanent teeth, hair alterations, hypertelorism, midface hypoplasia, abnormal EEG, syndactyly, and other findings. Her mother had minor anomalies which could represent the mild expression of a gene. A review on the conditions combining ectodermal dysplasia and cleft lip/palate is presented.

Blepharo-cheilo-dontic (BCD) syndrome: Report on four new patients

“…Facial clefting with variable eyelids and teeth involvement, as isolated case or inherited as autosomal dominant trait, has been noted previously in several cases reports [Picó, 1959;Allanson and McGillivray, 1985;Martinez et al, 1987;Falace and Hall, 1989;Korula et al, 1995;Gorlin et al, 1996].…”

Rapp‐Hodgkin syndrome: Report of a Brazilian family

“…Other conditions involving ectodermal dysplasia/clefting/limb anomalies such as the EEC syndrome, the Bowen-Armstrong syndrome, the Rosselli and Gulienetti syndrome, the Ftira syndrome, the Martinez syndrome, and the ZlotogoraOgur syndrome [Rosselli and Gulienetti, 1961;Farti, 1971;Bowen and Armstrong, 1976;Richieri-Costa et al, 1986;Martinez et al, 1987;Zlotogora et al, 1987;Ogur and Yuksel, 19881 can be differentiated by the clinical picture as a whole, and in some instances by the pattern of inheritance. Clefting patients with minor ectodermal dysplasia must be carefully examined, considering the risks involved in the RHS, and counseled accordingly.…”

Autosomal recessive ectodermal dysplasia, cleft lip/palate, mental retardation, and syndactyly: The Zlotogora‐Ogur syndrome

“…Ectodermal dysplasia, cleft lip/palate, mental retardation and limb anomalies have been reported as component manifestations of several disorders [Rosselli and Gulienetti, 1961;F'reire-Maia, 1970: Bowen andArmstrong, 1976;Michels et al, 1978;Martinez et al, 1987;Zlotogora et al, 1987;Ogur and Yuksel, 19881. However, the cluster of anomalies presented by the patients here reported, as well as the inheritance (autosomal recessive), has been observed infrequently [Zlotogora et al, 1987;Ogur and Yuksel, 19881.…”