East Africa region is facing an unprecedented triple socioeconomic threat caused by the combined effects of the ongoing COVID-19 pandemic, the upsurge of desert locusts, and recent severe floods. The socioeconomic impacts of the COVID-19 pandemic with the massive economic impacts of desert locust, and flooding resulted in devastating implications on livelihood and food security situation in East Africa. The overall objective of this review is to assess and compile the widespread socioeconomic impacts of the three threats in East Africa evidence from Ethiopia. To achieve this objective, in this review, all relevant information were collected through different search engines of PubMed/PMC/Medline, Web of Science, Google Scholar, Scopus, Google, and Science Direct databases. In addition, local media news, reports relevant to the topic from local and national governments, international organizations, and NGOs were used. The review found that the threats do not just have short-term impacts on socioeconomic conditions of the people in the region in general and in Ethiopia in particular, they exacerbate prevailing food insecurity and undermine livelihoods and development gains that took years to build. Restriction measures introduced by governments to contain the spread of Andualem Kassegn ABOUT THE AUTHORS Andualem Kassegn is a full-time lecturer and researcher in the Department of Agricultural Economics, at Woldia University, Ethiopia. He has an MSc degree in Agricultural Economics from Wollo University and a BA degree in Economics from Mekelle University. Currently, he has been teaching several Agricultural Economics courses. His research areas of interest are lie in researching livelihood and income diversifications, impact evaluations, food security, and poverty matters, etc. Ebrahim Endris is a full-time lecturer and researcher in the Department of Agricultural Economics, at Woldia University, Ethiopia. He has an MSc degree in Agricultural Economics from Haramaya University and BSc degree in Agricultural Economics from the same University. Currently, he has been teaching several Agricultural Economics courses. His research areas of interest are lie in researching market analysis, value chain analysis, food security and poverty, livelihood diversifications, impact evaluations, etc. PUBLIC INTEREST STATEMENT This review article explores the triple impacts of the COVID-19 pandemic, desert locusts, and floods in East Africa mainly focus on Ethiopia. The review revealed that these threats are currently devastating the socioeconomic situations of millions of people in East Africa in general and in Ethiopia in particular. This review found that the worst affected groups by the threats were smallholder households, children, youths, women, migrants, informal workers, and microsmall and medium-sized enterprises. Therefore, this review article calls interventions of governments, international organizations, stakeholders, NGOs and provides possible suggestions for researchers to research in the future to reduce the short and ...