The precise knowledge of the beginning and the end of the growing season is necessary for the calculation of climatic indicators with evident effect on grapevine production. The aim of this study is to develop suitable methods on the basis of thermal conditions that can be used for calculation of the beginning, the end, and the length of the growing season for every single year. The two most accurate methods ('5mid' and 'int') are selected using the root-mean-square error compared to the reference growing season values based on averaging the daily mean temperature for several decades. In case of the '5mid' method, the beginning (or the end) is the middle day of the first (or last) 5-day period with temperature not less than 10 °C. In case of the 'int' method, the beginning (or the end) of the growing season is the day after March 15 (or September 15), when the smoothed series of daily temperature using the monthly average temperatures of March and April (or September and October) exceeds 10 °C (or falls below 10 °C). As a next step, several climatic indicators (e.g., Huglin index and hydrothermal coefficient) are calculated for Hungary for three time periods (1961−1990, 2021−2050, and 2071−2100*) using the '5mid' and 'int' methods. For this purpose, the bias-corrected daily mean, minimum, and maximum temperature and daily precipitation outputs of three different regional climate models (RegCM, ALADIN, and PRECIS) are used. Extreme temperature and precipitation