Clinical advantages of using mini-bypass systems in terms of blood product use, postoperative bleeding and air entrainment: an in vivo clinical perspective☆

Abstract

The adoption of mini-bypass significantly potentially reduces hemodilution, donor blood usage, postoperative bleeding and exposure to GME in routine CABG patients as compared to the use of conventional extracorporeal circulation circuits.

Minimized extracorporeal circulation system in coronary artery bypass surgery: a 10-year single-center experience with 2243 patients

“…In several studies, the transfusion rate for different MECC systems could be reduced to 30-50% in comparison to standard CPB [14,15]. Several studies demonstrated that blood transfusion is an independent predictor of postoperative morbidity and mortality and, especially after CABG, every unit of RBC transfused is associated with an incrementally increased risk for adverse outcome [16,17].…”

O impacto da hemotransfusão na morbimortalidade pós-operatória de cirurgias cardíacas

“…The use of antifibrinolytic, such as aprotinin, attenuates the systemic inflammatory response in patients undergoing EC [26]. The use of miniEC (reduction of the prime, the tubes and vacuum drainage) and the use of centrifugal pumps (Bio Pump) can reduce the excessive use of heparin [27,28]. Hypothermia (between 30° and 32° C) during the surgical procedure may also reduce bleeding during surgery and in the postoperative period.…”

Gaseous microemboli in cardiac surgery with cardiopulmonary bypass: the use of veno-arterial shunt as a preventive method

“…This evolution of new knowledge minimized the deleterious effects of CPB and with the addition of accessories such as arterial filters and bubble detectors; it has reduced the morbimortality in cardiac surgery procedures with CPB [38,[43][44][45]. However, the incidence, still frequent of neurological complications remains a challenge because, despite all the advances, neurologic complications still occur and are causes of serious damage [4].…”