Clinical analysis of small-sized peripheral lung cancer

Abstract

Compared with the patients with lesions 2.1 to 3 cm in diameter, the patients with small-sized lung cancer had a milder progressive state and a better prognosis.

Lobectomy and limited resection in small-sized peripheral non-small cell lung cancer

“…Previous studies reported better postoperative outcomes and less pathological invasiveness in NSCLC patients with tumors ≤2 cm than in those with larger tumors (2.1-3 cm) (4,16). Favorable postoperative prognosis was evident even in patients with small tumors undergoing limited resection (17).…”

Video-assisted thoracoscopic surgery (VATS) segmentectomy for small peripheral lung cancer tumors: intermediate results

“…Regional recurrence may be caused by intrapulmonary metastasis in segments other than the Table 4 for details b Patients in the compromised group did not undergo systemic lymph node dissection specimen segment(s) in the same lobe, by regional lymph node metastasis, or by an incomplete resection margin. The incidence of regional lymph node metastasis and intrapulmonary metastasis in the same lobe has been reported to be 2% and 10%, respectively, in cases of stage I NSCLC [1,9,17,19,20,23]. In our own series of pathologic investigations of 101 stage I NSCLC patients who underwent lobectomy, intrapulmonary metastasis in the resected lobe was found in 2% of patients and mediastinal or lobar lymph node metastasis was found in 10.9%.…”

Results of surgical treatment for small (2 cm or Under) adenocarcinomas of the lung

“…A lobectomy is the standard surgical procedure even for small lung cancers, because some studies have demonstrated progressive disease in 10%-20% of patients with small lung cancers. 4,8 Many reports defi ne small lung cancers as having a maximum diameter of 2 cm or less, [1][2][3][4]8 and since adenocarcinoma has been reported to account for 85%-90% of small peripheral lung cancers, 1-3 in this study we restricted our analysis of small peripheral lung cancers to adenocarcinomas. Postoperatively, 89% of the patients (465) had stage IA disease, while the other 11% had progressive disease.…”

“…The overall 5-year survival rate of the patients in the present study was 83.6%. Koike et al 4 reported a 5-year survival rate of 79.5% for patients with peripheral cT1N0M0 lung cancer having a maximum diameter of 2 cm or less. Okada et al 12 reported a 5-year survival rate of 87.3% for patients with cT1N0M0 non-small cell carcinoma 2 cm or less in diameter who underwent an extended segmentectomy, and of 77.7% for those who underwent a lobectomy.…”

“…2,3 Controversy still exists regarding the indications for lesser pulmonary resection in patients with small lung cancers, because even small lung cancers entail the possibility of progressive disease. 4 Adenocarcinoma accounts for as many as 85%-90% of small peripheral lung cancers, 1-3 and we performed a retrospective analysis of small peripheral adenocarcinomas of the lung. The objectives of this study were to identify the clinicopathologic characteristics and signifi cant prognostic factors of small (2 cm or less in diameter) adenocarcinomas treated by a complete resection, and furthermore to assess the acceptability of performing a limited pulmonary resection in such patients.…”