Clinical and bacteriological efficacy of 5-day telithromycin in acute maxillary sinusitis: a pooled analysis

Roos, Kristian; Tellier, Guy; Baz, Malik; Leroy, Bruno; Rangaraju, Manickam

doi:10.1016/j.jinf.2004.05.014

Cited by 18 publications

(8 citation statements)

References 29 publications

(12 reference statements)

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“…128 Similar findings have been noted in other trials, with similar resolution rates up to 3 weeks after treatment regardless of therapy duration. 48,[129][130][131] When 5 days of antibiotic therapy is compared with 10 days, similar success rates are again observed. 128 Adverse events are common with antibiotic therapy, but the diverse reporting among studies precludes meaningful comparisons of rates across different antibiotic classes.…”

Section: Duration Of Therapy and Adverse Eventsmentioning

confidence: 88%

Clinical Practice Guideline (Update): Adult Sinusitis

Rosenfeld

Piccirillo

Chandrasekhar³

et al. 2015

Otolaryngol.--head neck surg.

930

1,303

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The update group made strong recommendations that clinicians (1) should distinguish presumed ABRS from acute rhinosinusitis (ARS) caused by viral upper respiratory infections and noninfectious conditions and (2) should confirm a clinical diagnosis of CRS with objective documentation of sinonasal inflammation, which may be accomplished using anterior rhinoscopy, nasal endoscopy, or computed tomography. The update group made recommendations that clinicians (1) should either offer watchful waiting (without antibiotics) or prescribe initial antibiotic therapy for adults with uncomplicated ABRS; (2) should prescribe amoxicillin with or without clavulanate as ﬁrst-line therapy for 5 to 10 days (if a decision is made to treat ABRS with an antibiotic); (3) should reassess the patient to confirm ABRS, exclude other causes of illness, and detect complications if the patient worsens or fails to improve with the initial management option by 7 days after diagnosis or worsens during the initial management; (4) should distinguish CRS and recurrent ARS from isolated episodes of ABRS and other causes of sinonasal symptoms; (5) should assess the patient with CRS or recurrent ARS for multiple chronic conditions that would modify management, such as asthma, cystic fibrosis, immunocompromised state, and ciliary dyskinesia; (6) should confirm the presence or absence of nasal polyps in a patient with CRS; and (7) should recommend saline nasal irrigation, topical intranasal corticosteroids, or both for symptom relief of CRS. The update group stated as options that clinicians may (1) recommend analgesics, topical intranasal steroids, and/or nasal saline irrigation for symptomatic relief of viral rhinosinusitis; (2) recommend analgesics, topical intranasal steroids, and/or nasal saline irrigation) for symptomatic relief of ABRS; and (3) obtain testing for allergy and immune function in evaluating a patient with CRS or recurrent ARS. The update group made recommendations that clinicians (1) should not obtain radiographic imaging for patients who meet diagnostic criteria for ARS, unless a complication or alternative diagnosis is suspected, and (2) should not prescribe topical or systemic antifungal therapy for patients with CRS.

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Section: Duration Of Therapy and Adverse Eventsmentioning

confidence: 88%

Clinical Practice Guideline (Update): Adult Sinusitis

Rosenfeld

Piccirillo

Chandrasekhar³

et al. 2015

Otolaryngol.--head neck surg.

930

1,303

View full text Add to dashboard Cite

show abstract

“…No significant differences have been noted, however, in resolution rates for ABRS with a 6-to 10-day course of antibiotics compared with a 3-to 5-day course (azithromycin, telithromycin, or cefuroxime) up to 3 weeks after treatment. [118][119][120] Another systematic review found no relation between antibiotic duration and outcome efficacy for 8 RCTs. 33 Conversely, shorter treatment courses of antibiotics are associated with fewer adverse effects.…”

Section: Other Considerationsmentioning

confidence: 99%

Clinical practice guideline: Adult sinusitis

Rosenfeld

Andes

Bhattacharyya

et al. 2007

Otolaryngol.--head neck surg.

874

913

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This clinical practice guideline is not intended as a sole source of guidance for managing adults with rhinosinusitis. Rather, it is designed to assist clinicians by providing an evidence-based framework for decision-making strategies. It is not intended to replace clinical judgment or establish a protocol for all individuals with this condition, and may not provide the only appropriate approach to diagnosing and managing this problem.

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“…The same applies to hew drugs such as telithromycin, which has been shown to be effective in adults at a dose of 800mg, once a day, for five days. [27][28][29] Other recommended treatments for acute sinusitis include hypertonic saline solution and topical nasal corticosteroids. Most of the studies that compared these approaches with antibiotics or placebo have been done in selected adult groups 1,2,5,30,31…”

Section: Sinusitismentioning

confidence: 99%

Otimizando o diagnóstico para o tratamento adequado das principais infecções agudas em otorrinopediatria: tonsilite, sinusite e otite média

Sih

Bricks

2008

Rev. Bras. Otorrinolaringol.

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As sinusites, otites médias agudas e tonsilites são muito freqüentes em crianças. A maioria dessas infecções é causada por vírus, mas em geral, elas são tratadas com antibióticos. O uso inapropriado de antibióticos favorece a seleção, crescimento e disseminação de bactérias resistentes que colonizam as vias respiratórias, atingindo toda a comunidade. A emergência de bactérias resistentes dificulta os tratamentos das infecções respiratórias, sendo essencial desenvolver estratégias efetivas para restringir o uso de antibióticos sem prejudicar as crianças que realmente precisam desses medicamentos. OBJETIVO: Analisar os resultados de estudos randomizados e controlados sobre critérios clínicos e laboratoriais utilizados para diagnóstico e tratamento das tonsilites, sinusites e otites. MÉTODOS: Levantamento dos estudos randomizados e controlados sobre o tema, publicados no MEDLINE e SCIELO, de 2000 a 2006. CONCLUSÕES: Como a maioria dessas infecções evolui bem sem antibióticos, deve-se evitar o uso desses medicamentos a menos que a criança pertença aos grupos de alto risco para complicações ou apresente persistência ou piora dos sintomas com tratamento sintomático. É necessário que os médicos e leigos conheçam melhor a evolução natural das infecções respiratórias agudas e que seja garantido o acesso das crianças a serviços médicos de boa qualidade para orientação e reavaliação, quando necessária.

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Clinical and bacteriological efficacy of 5-day telithromycin in acute maxillary sinusitis: a pooled analysis

Cited by 18 publications

References 29 publications

Clinical Practice Guideline (Update): Adult Sinusitis

Clinical Practice Guideline (Update): Adult Sinusitis

Clinical practice guideline: Adult sinusitis

Otimizando o diagnóstico para o tratamento adequado das principais infecções agudas em otorrinopediatria: tonsilite, sinusite e otite média

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