Clinical and biochemical profile of Indians with type 2 diabetes mellitus: A problem lurking for India

Singh, Sandeep; Singh, Ajay Pal; Multani, Manish Kishore; Purohit, Ashish

doi:10.4103/1119-0388.140424

Cited by 5 publications

(6 citation statements)

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“…Higher mean BMI (Ganz et al 2014;Singh et al 2014) and increased prevalence of obesity Ganz et al 2014;Nandimath et al 2016;Awasthi et al 2017) observed earlier in T2DM patients when compared to controls is also apparent in the present study. It was observed that while T2DM patients show higher BMI than the controls of the same ethnic group, normal BMI was observed in Japanese T2DM patients and the difference was attributed to the difference in insulin secretion and action between two ethnic groups (Sone et al 2003).…”

Section: Type 2 Diabetessupporting

confidence: 81%

Analysis of Modal Choice of Residents in Lagos State

Olatoye¹

2019

JHE

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We investigated the role of Body mass index (BMI) in non-communicable diseases-polycystic ovary syndrome (PCOS), type 2 diabetes (T2DM) and coronary artery disease (CAD). Using a case control design, we compared mean BMI and its categories, in gender and disease specific samples, and computed odds ratios as well as receiver operator characteristic (ROC) curve. The 95 percentile cut off values were also determined but only for controls. We found mean BMI and prevalence of obesity to be higher in PCOS and T2DM and lower in CAD cases than controls. The ROC analysis suggested gender specific cut-off values are more sensitive than pooled sample. The area under the ROC curve which is highly significant suggests predictive utility of the BMI cut off values both for PCOS and T2DM.

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Section: Type 2 Diabetessupporting

confidence: 81%

Analysis of Modal Choice of Residents in Lagos State

Olatoye¹

2019

JHE

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Section: Discussionsupporting

confidence: 88%

“…3 The male to female ratio in this study was 1.78:1 which is comparable to the various studies done in India. 3,4,5 The presence ECG change in subjects with type 2 diabetes in this study was 52%. Overall all ECG changes were more common among the cases when compared to controls, but few changes which did not have statistical significance but were more common among the cases were heart blocks(6% v/s 4%) and chamber enlargement (6% v/s 2%).…”

Section: Discussionsupporting

confidence: 88%

A study of electrocardiographic changes in type 2 diabetes patients

2015

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“…Sandeep Singh et al, in their case control study showed that the body mass index (BMI) of the study subjects (diabetics) was 23.94±1.83 kg/m 2 and that of controls was 22.8±1.38 kg/m 2 (p<0.001). 8 The results are comparable to this study. In Study Group a statistically highly significant negative correlation was observed between BMI and Serum Total Testosterone levels (Correlation Coefficient = -0.645, p value <0.001) and, between BMI and serum Free Testosterone levels (Correlation Coefficient = -0.567, p value <0.001).…”

Section: Discussionsupporting

confidence: 86%

Estimation of serum testosterone concentration in type 2 diabetic males

2020

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Background: A high incidence of hypogonadism in men with Type 2 Diabetes Mellitus has been globally reported. The present study was aimed at determining the frequency of hypogonadism in T2DM males. Screening and management of hypogonadism in Diabetic males should be done.Methods: In this case control study conducted from January 2018 to August 2019 at SGRDIMSR Sri Amritsar 100 Type 2 Diabetic males were taken as cases. 50 age matched nondiabetic males were taken as controls. Apart from BMI and waist hip ratio routine investigations, HbA1C, serum total and free testosterone levels were done. All the subjects were subjected to ADAM questionnaire to evaluate for hypogonadism.Results: Majority of subjects were in the age of 40-50 years. Mean Serum Total Testosterone levels in Study and Control Groups were 4.94±5.32 nmol/L and 6.63±4.54 nmol/L respectively (p=0.045). Mean Serum Free Testosterone levels in Study and Control Groups were 4.12±3.43 pg/ml and 6.05±3.24 pg/ml respectively (p=0.001). A statistically highly significant negative correlation was found between BMI and Serum Testosterone levels in both groups. Prevalence of hypogonadism (Total Testosterone <4.56 nmol/L) in Study and Control Groups was 73% and 58% respectively. Sensitivity and specificity of ADAM questionnaire was found to be 78.46% and 94.29 % respectively.Conclusions: Prevalence of hypogonadism among T2DM males is high. So, screening for hypogonadism should be done. ADAM questionnaire can be used as a screening tool, results must be confirmed with Serum Total Testosterone levels.

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Clinical and biochemical profile of Indians with type 2 diabetes mellitus: A problem lurking for India

Cited by 5 publications

References 0 publications

Analysis of Modal Choice of Residents in Lagos State

Analysis of Modal Choice of Residents in Lagos State

A study of electrocardiographic changes in type 2 diabetes patients

Estimation of serum testosterone concentration in type 2 diabetic males

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