Clinical and dermatoscopic patterns of alopecia areata: A tertiary care centre experience

Hegde, Spandana P; Naveen, K; Athanikar, Sharatchandra B; Reshme, Priyanka

doi:10.4103/0974-7753.125608

Cited by 28 publications

(25 citation statements)

References 10 publications

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“…[91011] However, some studies reported lesser incidence. [71213] This variation in results can be attributed to the difference in skin types (yellowish color of skin in Asians may make it difficult to perceive the YDs on dermoscopy), different shampooing habits, and difference in the type of dermoscope used. [714] In view of their higher frequency in AA as reported by various studies including ours, YD can be regarded as a sensitive marker for the diagnosis of AA.…”

Section: Discussionmentioning

confidence: 99%

“…Some studies reported lesser incidence. [71112] These variations in results may be due to difference in activity, severity, and duration of the disease in various studies. [15]…”

Section: Discussionmentioning

confidence: 99%

“…In the present study, SVH was seen in 66% of the patients, similar to Hegde et al . [12] study. Peter et al .,[13] and Mane et al .…”

Section: Discussionmentioning

confidence: 99%

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Evaluation of clinical significance of dermoscopy in alopecia areata

et al. 2016

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Background:Alopecia areata (AA) is a common, chronic inflammatory disease characterized by nonscarring hair loss on the scalp or any hair-bearing area of the body. Recently, dermoscopy, a noninvasive diagnostic procedure, has been employed for the diagnosis of AA.Aim:To evaluate various dermoscopic patterns in AA and correlate these patterns with the disease activity and severity.Materials and Methods:Dermoscopy was performed on AA patients using DL1 dermoscope (magnification ×10 was used). The dermoscopic patterns recorded were analyzed to identify any correlation with the disease activity and severity.Results:A total of fifty patients of AA were recruited in the study. Female outnumbered males with the ratio being 1.173:1. Mean age of the patients was 25.06 years. Mean duration of disease was 14 months. The most common site involved was scalp (80%) and type noted was patchy (84%). Various dermoscopic patterns noted were yellow dots (YD) (88%), short vellus hair (66%), black dots (BD) (58%), broken hairs (BHs) (56%), tapering hair (TH) (26%), Coudability hairs (14%), pigtail hair (14%), and Pohl-Pinkus constrictions (2%). Statistically significant correlation was observed between BD, BHs, THs, and disease activity. No significant correlation was found between severity and any of the dermoscopic features.Conclusion:The most common dermoscopic pattern in our study was YD. Presence of BDs, BHs, and THs indicate active disease. Dermoscopic patterns were not affected by severity of the disease.

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Section: Discussionmentioning

confidence: 99%

“…Some studies reported lesser incidence. [71112] These variations in results may be due to difference in activity, severity, and duration of the disease in various studies. [15]…”

Section: Discussionmentioning

confidence: 99%

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Evaluation of clinical significance of dermoscopy in alopecia areata

et al. 2016

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“…The patients were diagnosed to have active alopecia areata by history of active hair loss within the past 6 months [ 9 ], positive pull test [ 10 ], exclamation mark hair seen clinically at the periphery of the lesions [ 11 ] and trichoscopic examinations showing black dots, broken hair and exclamation marks [ 12 ]. The extent of the scalp involvement was further evaluated using the Severity Alopecia Tool (SALT) [ 13 , 14 ].…”

Section: Methodsmentioning

confidence: 99%

Serum level of interleukin-15 in active alopecia areata patients and its relation to age, sex, and disease severity

Ragab¹,

Hassan²,

Niely³

et al. 2020

pdia

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Introduction Autoimmune mechanisms with evident genetic background are the main components of alopecia areata (AA) pathogenesis. Interleukin 15 (IL-15) is considered as an important signalling cytokine. Its disordered expression has been linked to inflammatory autoimmune disorders. Aim The present study aimed to evaluate serum IL-15 in active AA patients and to assess its association with patients’ sex, age, and disease severity. Material and methods IL-15 serum level was measured in 40 patients with active alopecia areata and 20 healthy controls using the ELISA technique. The severity of hair loss was assessed in accordance with the Severity of Alopecia Tool (SALT). Results A significantly higher serum level of IL-15 in AA patients than in controls was detected ( p < 0.001). A significant positive correlation was detected between the SALT score and IL-15 serum level ( r s = 0.433, p = 0.005). No significant correlation between age of the patients and the serum level of IL-15 was observed ( r s = 0.224, p = 0.164). No significant difference in IL-15 serum level regarding patients’ sex, history of disease recurrence, or family history of AA was noted. Conclusions The elevated serum level of IL-15 in active AA patients might reflect its role in disease pathogenesis as a key signalling cytokine. Its level is correlated with disease severity. However, IL-15 is not influenced by patients’ gender or age.

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“…They represent increased follicular blood supply and their presence signify a better prognosis with respect to hair regrowth. 8,9 Androgenetic alopecia (AGA) is characterized by hair diameter diversity due to miniaturization of the hair follicles. Variability in hair shafts diameter of more than 20% is diagnostic of this condition.…”

Section: Introductionmentioning

confidence: 99%

Trichoscopy in common scalp alopecia: an observational study

2020

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Background: Many patients of alopecia are encountered in daily practice with diagnostic dilemma. Trichoscopy is a sensitive, non-invasive tool which aids in clinical diagnosis.Methods: An observational study performed in adult patients with alopecia attending R.D. Gardi Medical College, Ujjain, over a period of one year. Trichoscopy was performed using a Dinolite digital microscope with both polarized and non polarized modes.Results: 269 patients of alopecia (257 non cicatricial, 12 cicatricial) aged 18-50 years were enrolled. The diagnosis was made after detailed history and clinical examination. 173 (64.3%) males and 96 (35.7%) females. 45.4% patients were diagnosed to have alopecia areata in which yellow dots were the most common trichoscopic finding observed in 88.5% patients. 37.2% patients were diagnosed with androgenetic alopecia with hair diameter diversity >20% observed in all the patients. 9.3% patients were diagnosed to have telogen effluvium with short vellus hair seen in 64% patients. 3.7% of the patients were diagnosed to have seborrheic dermatitis with arborizing vessels being the most common finding seen in 90% patients. 2.9% patients were diagnosed with lichen planopilaris in which loss of follicles and peritubular white casts were seen in all the cases. 0.9% patients were diagnosed to have discoid lupus erythematosus with hyperkeratotic follicular plugging seen in all the cases. Overall yellow dots were the most common trichoscopic findings seen in 61% cases.Conclusions: Trichoscopy is a reliable diagnostic tool in hair and scalp disorders. Hence trichoscopic evaluation should be done in every case of alopecia.

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Clinical and dermatoscopic patterns of alopecia areata: A tertiary care centre experience

Cited by 28 publications

References 10 publications

Evaluation of clinical significance of dermoscopy in alopecia areata

Evaluation of clinical significance of dermoscopy in alopecia areata

Serum level of interleukin-15 in active alopecia areata patients and its relation to age, sex, and disease severity

Trichoscopy in common scalp alopecia: an observational study

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