Clinical and economic outcomes of hospital pharmaceutical care: A systematic review and meta-analysis

Abstract

Background: Hospital clinical pharmacists have been working in many countries for many years and clinical pharmaceutical care have a positive effect on the recovery of patients. In order to evaluate the clinical effectiveness and economic outcomes of clinical pharmaceutical care, relevant clinical trial studies were reviewed and analysed. Methods: Two researchers searched literatures published from January 1992 to October 2019, and screened them by keywords like pharmaceutical care, pharmaceutical services, pharmacist interventions, outcomes, effects, impact, etc. Then, duplicate literatures were removed and the titles, abstracts and texts were read to screen literatures according to inclusion and exclusion criteria. Key data in the literature were extracted, and Meta-analysis was conducted using the literature with common outcome indicators.Results: A total of 3299 articles were retrieved, and 42 studies were finally included. Twelve of them were used for meta-analysis. Among the 42 studies included, the main results of pharmaceutical care showed positive effects, 36 experimental groups were significantly better than the control group, and the remaining 6 studies showed mixed or no effects. Meta-analysis showed that clinical pharmacists had significant effects on reducing systolic blood pressure and diastolic blood pressure and shortening hospitalization days (P<0.05), but no statistical significance in reducing medical costs (P>0.05).Conclusion: clinical pharmacists' pharmaceutical care has a significant positive effect on patients' clinical effects, but has no significant economic effect.

Pharmacist‐led interventions to improve medication adherence in older adults: A meta‐analysis

“…In addition, pharmacist‐led interventions had statistically significant beneficial effects on quality of life and blood pressure values in older adults. Overall, our results add to a growing literature on the positive impact of pharmacists on health outcomes 58–62 …”

“…Overall, our results add to a growing literature on the positive impact of pharmacists on health outcomes. [58][59][60][61][62] When implementing interventions, it is important to understand the components driving any beneficial effect on health outcomes. A previous meta-analysis of interventions to improve medication adherence in older adults showed larger effect sizes for interventions employing special medication packaging, dose modification, patient self-monitoring of medication-taking, and written instructions.…”

Economic impact of pharmaceutical interventions on healthcare services from Brazil: a systematic review

“…36 In a meta-analysis conducted with 42 studies, the intervention of the clinical pharmacist had a significant effect on lowering blood pressure and reducing hospitalization days. 37 In general, the economic evaluations included in this review showed variable methodological quality. A previous systematic review, which included economic evaluations of pharmaceutical services in community pharmacies, also found a wide divergence in the quality and level of uncertainty in the studies.…”

Nutrição parenteral: contribuições do cuidado farmacêutico

“…O cuidado farmacêutico é a prestação direta e responsável de medicamentos aos usuários com o objetivo de alcançar resultados definidos (Guedes, Brito & Silva, 2020;Lin et al, 2020). A identificação, a resolução e a prevenção de problemas relacionados aos medicamentos resulta ganhos clínicos, humanísticos e econômicos na assistência à saúde (Juanes et al, 2018;Messerli, Vriends & Hersberger, 2018;Nogueira et al, 2020;Barros, Silva & Leite, 2020).…”