Clinical and laboratory findings in cases of toxic mastitis in cows in Northern Ireland

Menzies, F. D.; McBride, S. H.; McDowell, S.W.J.; McCoy, M. A.; McConnell, William J.; Bell, Catriona

doi:10.1136/vr.147.5.123

Cited by 16 publications

(27 citation statements)

References 23 publications

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“…Our study is in agreement with previous studies of cows with experimentally induced and naturally occurring ACM, for which leukopenia, neutropenia, lymphopenia have been reported [3,7]. Smith et al [10] recommended that routine hematological analysis is useful in guiding initial treatment decisions, particularly in valuable cows or when cows are hospitalized.…”

Section: Discussionsupporting

confidence: 83%

Classification of acute clinical mastitis on the base of vital signs and complete blood count test in dairy cows

Hur¹,

Kang²,

Jung³

et al. 2013

Korean Journal of Veterinary Research

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: This study was carried out to evaluate the diagnosis of acute clinical mastitis (ACM) which was based on the vital signs and complete blood count (CBC) tests in dairy cows. Twenty eight dairy cows diagnosed with ACM, were selected for the study between Jan 2003 and July 2006 in the National Institute of Animal Science. Based on their vital signs (rectal temperature, depression, rumen contraction and, dehydration status), ACM was divided into three different classes; mild, moderate and severe forms. In addition, ACM cows were subjected to CBC tests for further diagnosis of ACM. Of the 27 dairy cows diagnosed with ACM, 3 cows were determined to have a mild form, while moderate and sever forms were each observed in twelve cows. Among of them, 4 cows died, 5 cows were culled and 18 cows were recovered. In the mild form, all haematological parameters were comparable with normal values. However, leukopenia, due to neutropenia and lymphocytopenia, appeared characteristically in the moderate and severe forms. Using the observation of vital signs in conjunction with CBC tests, the diagnosis of ACM is more accurate, and is helpful in making decisions of whether treatment or culling of dairy cows infected with ACM is most appropriate.

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Section: Discussionsupporting

confidence: 83%

Classification of acute clinical mastitis on the base of vital signs and complete blood count test in dairy cows

Hur¹,

Kang²,

Jung³

et al. 2013

Korean Journal of Veterinary Research

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“…Studies on spontaneous or experimental E. coli mastitis have shown that affected cows can be divided into mild or severe responders, based on their clinical signs and disease outcome [8,26,34,35]. Periparturient cows and those in early lactation most frequently show severe clinical signs and even fatal outcome [4,7,18]. The observed systemic and local clinical reactions result from the acute phase reaction (APR), which is the response of the host to any tissue injury caused by trauma or inflammation [32].…”

Section: Introductionmentioning

confidence: 99%

“…Differences in the production, function and kinetics of cytokines and APP may explain the varying local and systemic signs of individual cows in E. coli mastitis [3,8,18,20,25]. We used an experimental LPS model to study local and systemic acute phase responses of dairy cows in different lactation stages.…”

Section: Introductionmentioning

confidence: 99%

Serum amyloid A and TNF? in serum and milk during experimental endotoxin mastitis

2004

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-A cross-over study was conducted to investigate the effect of intramammarily infused lipopolysaccharide (LPS) on the acute phase reaction in early (EL) and in late (LL) lactation. Nine cows received intramammary injections of 100 µg of Escherichia coli 0111:B4 LPS during EL and LL. The severity of each cows systemic and local signs and change in milk appearance were recorded and scored throughout the experiment. Systemic and local signs were found to be more serious in EL cows. Tumor necrosis factor α (TNFα) was detected in milk but not in serum. Serum amyloid A (SAA) concentrations increased both in serum and in milk. The milk TNFα concentrations peaked at 8 h post-challenge (PC). SAA concentrations started to increase at 8 h PC, and peak concentrations were seen at 32 and 48 h PC in milk and serum, respectively. The milk TNFα and SAA seemed to be correlated, being on average higher in EL. Serum SAA concentration was not correlated with milk TNFα or SAA, nor with the severity of local or systemic signs, but was correlated with changes in milk appearance. LPS / mastitis / dairy cow / SAA / TNFα

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“…L. monocytogenes has been described as a “ less common cause” of bovine environmental mastitis and may often be associated with the accidental introduction of the organism during intramammary infusion [25]. Mild persistent, antibiotic resistant, low grade infections have been documented in cattle and may result in decreased production from infected mammary tissue over time.…”

Section: Discussionmentioning

confidence: 99%

A case of bovine raw milk contamination with Listeria monocytogenes

et al. 2012

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During routine sampling of bulk raw milk on a dairy farm, the pathogenic bacteria Listeria monocytogenes was found to be a contaminant, at numbers < 100 cfu/ml. A strain with an indistinguishable pulsed-field gel electrophoresis pattern was isolated from the bulk milk two months later. Environmental swabs taken at the dairy environment were negative for the presence of L. monocytogenes, indicating a possible case of excretion of the L. monocytogenes directly into the milk. Milk samples were collected from the individual cows and analysed, resulting in the identification of L. monocytogenes excretion (at 280 cfu/ml) from one of the 4 mammary quarters of one dairy cow out of 180. When the infected cow was isolated from the herd, no L. monocytogenes was detected from the remaining herd. The pulsed-field gel electrophoresis pattern of the strain from the individual cow was indistinguishable from that originally isolated from the bulk milk. The infected cow did not show any clinical signs of disease, nor did the appearance of the milk have any physical abnormalities. Antibiotic treatment of the infected mammary quarter was found to be ineffective. This study shows that there can be risks associated with direct contamination of raw milk with L. monocytogenes.

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Clinical and laboratory findings in cases of toxic mastitis in cows in Northern Ireland

Cited by 16 publications

References 23 publications

Classification of acute clinical mastitis on the base of vital signs and complete blood count test in dairy cows

Classification of acute clinical mastitis on the base of vital signs and complete blood count test in dairy cows

Serum amyloid A and TNF? in serum and milk during experimental endotoxin mastitis

A case of bovine raw milk contamination with Listeria monocytogenes

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