This study aimed to evaluate the clinical and radio graphical outcome of cats following TPLO surgery for cranial cruciate ligament deficiency. Each cat underwent orthopedic assessment, pre-operative radio graphical evaluation, surgical procedure, postoperative management and clinical re-examination 1, 2, and 12 months following surgery. Age, body weights, TPAs, meniscal tears, implants and osteoarthritis progression were recorded. Postoperative OA score was compared with that obtained 1 year after surgery using a paired t-test with commercially available software. Radio graphical evaluation performed 1 year after surgery showed no significant OA progression (P-value > 0.1). Minor complications occurred in one case (#7) in which a mild to moderate seroma was observed ten days after surgery. No major complications were recorded. Although TPLO surgery in cats remains controversial, this study suggests that it was a suitable option for surgical treatment of feline cranial cruciate ligament rupture, but considering the ex vivo outcomes recently published, further in vivo evaluation is strongly recommended.