Clinical antibacterial effectiveness and biocompatibility of gaseous ozone after incomplete caries removal

Krunic, Jelena; Stojanović, Nenad; Djukic, Ljiljana; Roganović, Jelena; Popović, Branka; Simić, Ivana; Stojić, Dragica Lj.

doi:10.1007/s00784-018-2495-x

Cited by 20 publications

(19 citation statements)

References 44 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Other studies show theefficacy of gaseous ozone in the reduction of Lactobacillus sp. in deep carious lesions to be similar to the efficacy of chlorhexidine [39]. On the other hand, Hauser-Gerspach et al point out in their research that there is no significant difference in the reduction of viable bacteria in cavitated carious lesions in children in vivo, while aqueous ozone seems to be more effective in some cases [71].…”

Section: Restorative Dentistrymentioning

confidence: 85%

“…as well as on the total population of bacteria. The data demonstrate that both applied treatmentprocedures caused a reduction in the number of bacteria, however, chlorhexidine was more effective [39]. In vivo experiments were also performed by Ajeti et al The antibacterial efficacy of ozone combined with 0.9% NaCl, 2% chlorhexidine or 2.5% NaOCl was compared.…”

Section: Gaseous Ozone Ozonated Water and Ozonated Oilmentioning

confidence: 90%

See 1 more Smart Citation

Application of Selected Nanomaterials and Ozone in Modern Clinical Dentistry

et al. 2021

View full text Add to dashboard Cite

This review is an attempt to summarize current research on ozone, titanium dioxide (TiO2), silver (Ag), copper oxide CuO and platinum (Pt) nanoparticles (NPs). These agents can be used in various fields of dentistry such as conservative dentistry, endodontic, prosthetic or dental surgery. Nanotechnology and ozone can facilitate the dentist’s work by providing antimicrobial properties to dental materials or ensuring a decontaminated work area. However, the high potential of these agents for use in medicine should be confirmed in further research due to possible side effects, especially in long duration of observation so that the best way to apply them can be obtained.

show abstract

Section: Restorative Dentistrymentioning

confidence: 85%

Section: Gaseous Ozone Ozonated Water and Ozonated Oilmentioning

confidence: 90%

Application of Selected Nanomaterials and Ozone in Modern Clinical Dentistry

et al. 2021

View full text Add to dashboard Cite

show abstract

“…Loncar, et al, (2008) and Makeeva, et al, (2017) recognize that, in restorative dentistry, gas acts as a disinfectant, is an excellent therapeutic option for primary caries injuries and enhances remineralization. Krunic, et al, (2018) add that it is biocompatible, provides a good antimicrobial effect and can reduce children's anxiety in dental treatment. Ozonized water can have a lethal effect on S. mutans and L. acidophilusa, proving its effectiveness in eliminating cariogenic microflora (AYKUT-YETKINER, et al, 2013).…”

Section: Resultsmentioning

confidence: 99%

Ozone Therapy – Ozone Applicability in Various Dental Specialties

Frota¹,

Ferreira²

2020

IJAERS

View full text Add to dashboard Cite

Ozone (O3) is an allotropic oxygen compound, found in abundance in the stratosphere and which, due to its antimicrobial, disinfectant and healing properties, provide therapeutic applications for more than 260 different pathologies. Ozone therapy is a technique that uses this gas, in its gaseous, aqueous and oily forms as a disinfection treatment option, being considered a safe, minimally invasive and conservative modality. This study aimed to review the literature on ozone therapy applied to dentistry, aiming to clarify its benefits and care during use as complementary therapy. For that, searches were carried out in databases addressing the theme proposed between 2007 and 2020, in three languages: Portuguese, English and Russian. It is concluded that Ozone therapy can be used safely and efficiently in dentistry as a complementary disinfection practice, without contraindications. Although laboratory studies have emerged as a promising potential for ozone in dentistry, more in-depth studies with standardized methodologies are needed to, in short, obtain more information about its applicability.

show abstract

“…Ozone is currently being discussed in dentistry as a possible alternative antiseptic agent. Recent investigations have reported antimicrobial effects on oral pathogens of both gaseous and aqueous forms of ozone, and the effectiveness of ozone in the treatment of oral diseases is currently a subject of intense research 35,36 …”

Section: Introductionmentioning

confidence: 99%

Antibiofilm effect of ozonized physiological saline solution on peri‐implant–related biofilm

Tonon

Panariello

Spolidório

et al. 2020

Journal of Periodontology

View full text Add to dashboard Cite

Background Removal of dental plaque and local application of local chemical adjuncts, such as chlorhexidine (CHX), have been used to control and treat peri‐implant disease. However, these methods can damage the surface properties of the implants or promote bacterial resistance. The application of ozone as an adjunctive treatment represents a new approach in the management of peri‐implantitis. Thus, the purpose of this study was to evaluate the antimicrobial effect of ozonized physiological saline solution in different concentrations against oral biofilms developed on titanium surface. Methods Single and multi‐species biofilms of Porphyromonas gingivalis, Fusobacterium nucleatum, and Streptococcus oralis were formed on titanium specimens for 5 days in anaerobic conditions. Biofilms were treated with ozonized saline solution at different concentrations (25, 50, and 80 μg/NmL), for 30 seconds and 1 minute. CHX (0.12%) and saline solution (0.89% NaCl) were used as positive and negative controls, respectively. Bacterial viability was quantified by colony forming units (CFU mL−1), and biofilm images were acquired by confocal laser scanning microscopy (CLSM). Data were analyzed by parametric test (ANOVA) with Tukey post‐hoc test (P < 0.05). Results Ozonized saline solution showed antibiofilm activity at a concentration of 80 μg/NmL for 30 seconds and 1 minute, reducing, mainly, Porphyromonas gingivalis viability, with 2.78 and 1.7 log10 CFU mL−1 of reduction in both single and multi‐species biofilms, respectively, when compared to the control (saline), whereas CHX reduced 1.4 and 1.2 log10 CFU mL−1. Conclusion Ozonized saline solution has antibiofilm activity, with better effect when applied for 1 minute at 80 μg/NmL, being a promising candidate therapy for the treatment of peri‐implant diseases.

show abstract

Clinical antibacterial effectiveness and biocompatibility of gaseous ozone after incomplete caries removal

Abstract: Ozone appears as effective and biocompatible cavity disinfectant in treatment of deep carious lesions by incomplete caries removal technique.

Cited by 20 publications

References 44 publications

Application of Selected Nanomaterials and Ozone in Modern Clinical Dentistry

Application of Selected Nanomaterials and Ozone in Modern Clinical Dentistry

Ozone Therapy – Ozone Applicability in Various Dental Specialties

Antibiofilm effect of ozonized physiological saline solution on peri‐implant–related biofilm

Contact Info

Product

Resources

About