Clinical Aspects, Medical and Surgical, in the Management of Battey-Type Pulmonary Disease

Rapid radiometric method for determining drug susceptibility of Mycobacterium avium-intracellulare

“…Furthermore, M. avium-intracellulare infections are recognized with increasing frequency in immunocompromised patients (16). Chemotherapy with up to six antimycobacterial drugs simultaneously has frequently proven to be unsuccessful, and surgical therapy is beneficial in only a minority of selected patients (2,7,14,17,23 Sensi-Disc microbial susceptibility disks (BBL) were utilized for the conventional method, except for the following disks, which were prepared in our labo-ratory: INH, 5 ,ug/ml; CS, 20 jig/ml; and CFZ, 1 .g/ml.…”

Treatment of unclassified mycobacterial infection of the lungs

“…In the only large series to be reported, 22% of 180 patients became 'sputum-negative' after treatment with streptomycin, isoniazid, and P.A.S. (Corpe and Liang, 1960). In the present series of 16 patients treated in this way, nine of whom had photochromogenic infections, the sputum became negative in six and there was one relapse.…”

“…Lewis, Laschd, Armstrong, and Dunbar (1960) performed 37 resections and one plombage on 38 patients infected with group III organisms and 87% were rendered 'sputumnegative'. Corpe and Liang (1960) operated on 25 patients, mainly with group III infections, and all who survived operation were rendered 'sputum-negative'. Law (1964) performed 101 operations on 98 patients and claimed a 94% success rate.…”

“…Law (1964) performed 101 operations on 98 patients and claimed a 94% success rate. Corpe (1964) operated on 330 patients with group III infections and concluded that surgical treatment had a 75% chance of success. In our patients a satisfactory surgical result was achieved in eight out of 10 cases.…”

“…Harrison, Reimann, Long, Lester, and Adams (1959) performed 14 resections which resulted in three bronchopleural fistulae and two other major complications. Corpe and Liang (1960) reported three fistulae and two haemorrhages after 38 operations, and Law (1964) had eight major complications after 101 operations. In the present series haemorrhage and bronchopleural fistula proved fatal in one patient treated surgically.…”