Clinical Characteristics and Genotypes of Rotaviruses in a Neonatal Intensive Care Unit

Abstract

Systemic illness signs such as feeding difficulty and neutropenia are specific for preterm infants with rotavirus infections. G4P[6] was exclusive, regardless of preterm birth or locations of infections. This study might be helpful in developing policies for management and prevention of rotavirus infections in NICUs.

Distinctive pattern of white matter injury in neonates with rotavirus infection

“…These findings were also found in T2-weighted fluid-attenuated inversion recovery images (C); however, the increased signal intensity was subtle. 2 Thus, the absence of enteric symptoms in most cases of this study does not contradict our conclusions. Instead, rotavirus was tested in all 18 patients in our study, as a result of a preventive policy imposed in our neonatal care unit, which requires routine screening of rotavirus infection in referred patients.…”

“…Neonates are vulnerable to seizures, as well as rotavirus infection 1,2 ; however, the connection between this virus and neurologic symptoms in neonates has not attracted much attention. Neonates are vulnerable to seizures, as well as rotavirus infection 1,2 ; however, the connection between this virus and neurologic symptoms in neonates has not attracted much attention.…”

Rationale for In-Neonatal Intensive Care Unit Administration of Live, Attenuated Rotavirus Vaccination

“…12 Premature infants infected with rotavirus illness while hospitalized in the neonatal intensive care unit (NICU) tend to display signs of feeding intolerance, bloody mucoid stools, and abdominal distention. [14][15][16][17][18] Outbreaks of nosocomial rotavirus illness associated with necrotizing enterocolitis in NICUs have also been documented. [16][17][18]…”

Rotavirus infection as a frequent cause of neonatal fever

“…15 Another Korean prospective observational study noted the similar finding that fever was the most common symptom in near-term and term newborns with RV infection exclusively of the G4P[6] strain. 16 In Indian studies, the neonatal strain was G10P [11] and its main symptoms were diarrhea and vomiting. 17,18 They did not describe fever as a symptom of RV infection.…”