Clinical characteristics and outcomes of the first two waves of the COVID-19 pandemic in a community hospital: a retrospective cohort study

Egoryan, Goar; Yanez‐Bello, Maria Adriana; Ozcekirdek, Emre; Poudel, Bidhya; Ozen, Ece; Trelles-Garcia, Daniela Patricia; Chung, Chul Won; Ginsburg, Beth Y.; Friedman, Harvey; Rodriguez‐Nava, Guillermo

doi:10.1016/j.ijregi.2022.02.001

Cited by 2 publications

(1 citation statement)

References 9 publications

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“…The majority of death occurred during the first wave. There was overall improvement in clinical outcomes in terms of ED visits, hospitalization, and mortality rate after the first wave, interrupted by each subsequent surge of infection [ 44 , 45 ]. The Omicron variant was highly infectious, but mortality rate was relatively low consistent with a previous report [ 46 , 47 ].…”

Section: Discussionmentioning

confidence: 99%

Characteristics of COVID-19 patients with multiorgan injury across the pandemic in a large academic health system in the Bronx, New York

Lu¹,

Buczek²,

Fleysher³

et al. 2023

Heliyon

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Section: Discussionmentioning

confidence: 99%

Characteristics of COVID-19 patients with multiorgan injury across the pandemic in a large academic health system in the Bronx, New York

Lu¹,

Buczek²,

Fleysher³

et al. 2023

Heliyon

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Retrospective analysis of epidemiologic features and clinical course of COVID-19 patients and comparison between vaccinated and unvaccinated patients

Di Costanzo,

Mazza,

Carbone

et al. 2023

Monaldi Arch Chest Dis

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At our Pneumology Department, we dealt with three waves of COVID-19 pandemics. The purpose of this study is to compare patients' epidemiological and clinical characteristics across waves and to assess the effect of vaccination on clinical presentation, course, and prognosis. From March 2020 to March 2022, a retrospective cohort study was conducted to compare patient characteristics. Based on the time of hospital admission, data from 456 patients were collected and divided into three groups (IW, IIW, and IIIW). In addition, we looked at the link between vaccination and clinical presentation and hospitalization outcome. The average age and comorbidities of patients increased, as did the worsening of respiratory conditions at admission (PaO2/FiO2 median 207 in IW, 95.5 in IIW, and 99 in IIIW). Continuous positive airway pressure (CPAP) was the primary respiratory support during the first wave, but an increase in the use of high flow nasal cannula and noninvasive ventilation was later observed, resulting in a higher hospital discharge rate and a lower intubation rate. Vaccinated patients had less severe COVID-19-related respiratory failure, a better clinical course, and a higher hospital discharge rate (71.4% in V-group vs 44.7% in NV-group, p<0.001). Patients' characteristics changed over the three waves, possibly due to virus mutations. The advancement of clinical and therapeutic management knowledge has contributed to a reduction in the severity of respiratory failure. The vaccination campaign improved the clinical course and reduced mortality.

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Clinical characteristics and outcomes of the first two waves of the COVID-19 pandemic in a community hospital: a retrospective cohort study

Cited by 2 publications

References 9 publications

Characteristics of COVID-19 patients with multiorgan injury across the pandemic in a large academic health system in the Bronx, New York

Characteristics of COVID-19 patients with multiorgan injury across the pandemic in a large academic health system in the Bronx, New York

Retrospective analysis of epidemiologic features and clinical course of COVID-19 patients and comparison between vaccinated and unvaccinated patients

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