Clinical characteristics and outcomes of continuous renal replacement therapy performed on younger children weighing up to 10 kg

Abstract

Background/aim This study aimed to investigate the clinical features, modality, complications, and effecting factors on the survival of children weighing up to 10 kg who received continuous renal replacement therapy (CRRT). Materials and methods This study was a retrospective observational study conducted in five pediatric intensive care units in tertiary hospitals in Turkey between January 2015 and December 2019. Results One hundred and forty-one children who underwent CRRT were enrolled in the study. The median age was 6 (range, 2–12) months, and 74 (52.5%) were male. The median weight of the patients was 6 (range, 4–8.35) kg and 52 (36.9%) weighed less than 5 kg. The most common indication for CRRT was fluid overload in 75 (53.2%) patients, and sepsis together with multiorgan failure in 62 (44%). The overall mortality was 48.2%. Conclusion Despite its complexity, CRRT in children weighing less than 10 kg is a beneficial, lifesaving extracorporeal treatment modality.