Clinical characteristics, maternal and neonatal outcomes of pregnant women with SARS-CoV-2 infection in Turkey

Abstract

OBJECTIVES: To evaluate clinical features, laboratory test results, maternal and neonatal outcomes of pregnant patients with the Coronavirus disease (COVID-19). BACKGROUND: COVID-19 is a highly contagious disease caused by a severe acute respiratory coronavirus 2 (SARS-CoV-2). Healthy pregnant women are more susceptible to developing COVID-19. METHODS: We reviewed clinical data from pregnant patients with a laboratory-confi rmed SARS-CoV-2, who were admitted to two tertiary care hospitals in Turkey. Demographic, clinical characteristics, laboratory test results, imaging fi ndings, treatment received, maternal and neonatal outcomes were collected. RESULTS: A total of 24 pregnant women were enrolled in this study. The mean maternal and gestational age was 26.9±5.37 years and 24.15 ± 10.61 weeks, respectively. Cough was observed as the most common symptom (n=15; 62.5 %). The lowest lymphocyte percentage was 20.83 ± 13.05 (%). Nine women have delivered by Caesarean section, while one had a vaginal birth. One woman with critical COVID-19 died 2 days later postpartum. The neonate had been transferred to neonatal intensive care unit and died within 24 hours of birth. CONCLUSION: Our fi ndings showed that except for one patient, the clinical course of COVID-19 during pregnancy was mild. Early hospitalization of pregnant women with confi rmed and suspected COVID-19, liberal testing for SARS-CoV-2, active management with a multidisciplinary team seemed to be critical to recovery (Tab. 3, Ref. 31).

Neonatal Outcomes of Pregnant Women With Confirmed Coronavirus Disease 2019: One-Year Experience of a Tertiary Care Center

“…12 In another study from Turkey, 75% of pregnant women participants were symptomatic and similar to the symptom ranking in our results, they also found that cough (62.5%) and fever (54.1%) were the most common symptoms during COVID-19 infection. 13 The results of this study showed that the rate of premature birth in pregnant women with confirmed COVID-19 was 10%. Similarly, in a study conducted with the early data in China, the premature birth rate was found to be 12.1%, and in the same study, PCR positivity in newborns was reported as 9%, similar to our results.…”

Maternal and neonatal outcomes of pregnant women with SARS-CoV-2 infection in our tertiary hospital

“…[1] In the study of Özsürmeli et al conducted in our country, preeclampsia was found 8.3%. [22] At the time of publication of the study by fiahin et al, 34.5% of the pregnancies were terminated. Preeclampsia was detected in 1 (10%) of 10 pregnant women who gave birth.…”

Comparison of the pregnancy outcomes of the patients with severe symptoms who received medical treatment for COVID-19 versus the patients with mild-moderate symptoms

“…Although a high number of COVID-19 during pregnancy were reported in Turkey, there are still few studies regarding maternal or perinatal outcomes of COVID-19 infection during pregnancy. [11,12] The study, including 533 patients, reported that most of the pregnant women diagnosed with COVID-19 had mild symptoms (95.5%), and only 0.5% of the cases had severe symptoms. [12] In our study, 40.4% of the patients diagnosed with COVID-19 suffered from severe symptoms.…”