Clinical curative effect of electroacupuncture combined with Zhizhukuanzhong Capsules for treating gastroesophageal reflux disease

Zhang, Chaoxian; Guo, Like; Guo, Xi; Guo, Xinglin; Li, Guangyan

doi:10.1016/s0254-6272(13)60039-4

Cited by 20 publications

(31 citation statements)

References 10 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Inter-group comparison also demonstrated that the MA treatment was associated with superior improvements in general health (55.0±18.0 vs 41.9±20.0, p=0.025) and body pain (57.0±31.1 vs 40.9±19.3, p=0.020) scores. Zhang et al 21 found that EA treatment had equivalent effects to WM treatment at the end of the intervention period, but superior effects during the 48 week follow-up period, with greater improvements in role physical (67±13 vs 55±21), role emotional (72±36 vs 64±18), vitality (71±23 vs 62±41) and body pain (84±20 vs 64±50) scores (all p<0.05). The results of the second study Zhang et al 20 were similar, with superior improvements in role physical (66.52±13.29 vs 54.87±11.34), role emotional (71.59±35.54 vs 63.55±27.74) and body pain (83.56±19.92 vs 73.85±39.51) scores (all p<0.05).…”

Section: Quality Of Lifementioning

confidence: 96%

See 1 more Smart Citation

Acupuncture for the Treatment of Gastro-Oesophageal Reflux Disease: A Systematic Review and Meta-Analysis

et al. 2017

View full text Add to dashboard Cite

Background Gastro-oesophageal reflux disease (GORD) is one of the most common diseases presenting to gastroenterology clinics. Acupuncture is widely used as a complementary and alternative treatment for patients with GORD. Objective To explore the effectiveness of acupuncture for the treatment of GORD. Methods Four English and four Chinese databases were searched through June 2016. Randomised controlled trials investigating the effectiveness of manual acupuncture or electroacupuncture (MA/EA) for GORD versus or as an adjunct to Western medicine (WM) were selected. Data extraction and quality evaluation were performed by two authors independently and RevMan 5.2.0 was used to analyse data. Results A total of 12 trials involving 1235 patients were included. Meta-analyses demonstrated that patients receiving MA/EA combined with WM had a superior global symptom improvement compared with those receiving WM alone (relative risk (RR) 1.17, 95% CI 1.09 to 1.26; p=0.03; six studies) with no significant heterogeneity (I2=0%, p=0.41). Recurrence rates of those receiving MA/EA alone were lower than those receiving WM (RR 0.42,95% CI 0.29 to 0.61; p<0.001; three studies) with low heterogeneity (I2=7%, p=0.34), while global symptom improvement (six studies) and symptom scores (three studies) were similar (both p>0.05). Descriptive analyses suggested that acupuncture also improves quality of life in patients with GORD. Conclusion This meta-analysis suggests that acupuncture is an effective and safe treatment for GORD. However, due to the small sample size and poor methodological quality of the included trials, further studies are required to validate our conclusions. Trial registration number PROSPERO Systematic review registration no. CRD42016041916.

show abstract

Section: Quality Of Lifementioning

confidence: 96%

“…Zhang et al 20 reported mild diarrhoea in three patients receiving WM during the initial stages of treatment, reported no adverse events.…”

Section: Adverse Eventsmentioning

confidence: 97%

Acupuncture for the Treatment of Gastro-Oesophageal Reflux Disease: A Systematic Review and Meta-Analysis

et al. 2017

View full text Add to dashboard Cite

show abstract

“…Two recent studies from China, where NERD accounts for >90% of the GERD patients, revealed that acupuncture significantly inhibited intraesophageal acid and bile reflux, improved GERD-related symptoms, and was safe and well tolerated. 60,61 In a recent study, the authors assessed the value of electroacupuncture in 480 GERD participants. 61 Electroacupuncture was delivered once daily for a period of 6 weeks.…”

Section: Acupuncturementioning

confidence: 99%

“…60,61 In a recent study, the authors assessed the value of electroacupuncture in 480 GERD participants. 61 Electroacupuncture was delivered once daily for a period of 6 weeks. The 24-hour intraesophageal pH, bile reflux, endoscopic grading, and symptom score were all significantly reduced at the end of treatment.…”

Section: Acupuncturementioning

confidence: 99%

Nonmedical Therapeutic Strategies for Nonerosive Reflux Disease

Maradey–Romero

Kale

Fass

2014

Journal of Clinical Gastroenterology

View full text Add to dashboard Cite

There has been a marked decline over the last several years in drug development for gastroesophageal reflux disease and specifically for nonerosive reflux disease (NERD), despite there being many areas of unmet need. In contrast, we have seen a proliferation, during the same period of time, in development of novel, nonmedical therapeutic strategies for NERD using cutting-edge technology. Presently, compliance and lifestyle modifications are readily available noninvasive therapeutic interventions for NERD. Other nonmedical therapies include, the Stretta procedure, transoral incisionless fundoplication, and the magnetic sphincter augmentation device (LINX). Antireflux surgery, in experienced hands, has been repeatedly shown to be efficacious in resolving NERD-related symptoms. Psychological therapeutic interventions and alternative medicine techniques, such as acupuncture, continue to show promise, especially in NERD patients who failed antireflux treatment.

show abstract

“…It has been shown in animal studies that ZZKZ decoction could accelerate gastric emptying . Previous randomized controlled study showed that ZZKZ combined with the acupuncture could effectively decrease the acid and bile reflux in gastroesophageal reflux patients . ZZKZ has also been commonly used in FD patients with postprandial distress syndrome (PDS) in clinical practice in China.…”

Section: Introductionmentioning

confidence: 99%

The efficacy of oral Zhizhu Kuanzhong, a traditional Chinese medicine, in patients with postprandial distress syndrome

Xiao

Shu

et al. 2018

J of Gastro and Hepatol

View full text Add to dashboard Cite

show abstract

Clinical curative effect of electroacupuncture combined with Zhizhukuanzhong Capsules for treating gastroesophageal reflux disease

Cited by 20 publications

References 10 publications

Acupuncture for the Treatment of Gastro-Oesophageal Reflux Disease: A Systematic Review and Meta-Analysis

Acupuncture for the Treatment of Gastro-Oesophageal Reflux Disease: A Systematic Review and Meta-Analysis

Nonmedical Therapeutic Strategies for Nonerosive Reflux Disease

The efficacy of oral Zhizhu Kuanzhong, a traditional Chinese medicine, in patients with postprandial distress syndrome

Contact Info

Product

Resources

About