Clinical, Demographic, and Familial Correlates of Bipolar Spectrum Disorders Among Offspring of Parents With Bipolar Disorder

Goldstein, Benjamin I.; Shamseddeen, Wael; Axelson, David; Kalas, Cathy; Monk, Kelly R.; Brent, David A.; Kupfer, David J.; Birmaher, Boris

doi:10.1097/00004583-201004000-00013

Cited by 27 publications

(38 citation statements)

References 52 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Correspondingly, two more recent studies performed by the team of the Pittsburgh Bipolar Offspring Study showed that subthreshold manic or hypomanic symptoms are an important diagnostic risk factor for subsequent onset of a manic, mixed or hypomanic episode onset . Also, major depressive episodes and disruptive disorders were found to be associated with BD conversion .…”

Section: Introductionmentioning

confidence: 91%

Baseline dimensional psychopathology and future mood disorder onset: findings from the Dutch Bipolar Offspring Study

Mesman

Nolen

Keijsers

et al. 2017

Acta Psychiatr Scand

View full text Add to dashboard Cite

show abstract

Section: Introductionmentioning

confidence: 91%

Baseline dimensional psychopathology and future mood disorder onset: findings from the Dutch Bipolar Offspring Study

Mesman

Nolen

Keijsers

et al. 2017

Acta Psychiatr Scand

View full text Add to dashboard Cite

show abstract

“…A recent meta‐analysis suggested that the most potent predictors were family history, an earlier age of onset and the presence of psychotic symptoms 574. There is an increased prevalence of BD among offspring of parents with BD 575, 576, 577. Although there is no uniform strategy for managing depression (or ADHD, anxiety, etc.)…”

Section: Specific Populationsmentioning

confidence: 99%

Canadian Network for Mood and Anxiety Treatments (CANMAT) and International Society for Bipolar Disorders (ISBD) 2018 guidelines for the management of patients with bipolar disorder

et al. 2018

View full text Add to dashboard Cite

The Canadian Network for Mood and Anxiety Treatments (CANMAT) previously published treatment guidelines for bipolar disorder in 2005, along with international commentaries and subsequent updates in 2007, 2009, and 2013. The last two updates were published in collaboration with the International Society for Bipolar Disorders (ISBD). These 2018 CANMAT and ISBD Bipolar Treatment Guidelines represent the significant advances in the field since the last full edition was published in 2005, including updates to diagnosis and management as well as new research into pharmacological and psychological treatments. These advances have been translated into clear and easy to use recommendations for first, second, and third‐ line treatments, with consideration given to levels of evidence for efficacy, clinical support based on experience, and consensus ratings of safety, tolerability, and treatment‐emergent switch risk. New to these guidelines, hierarchical rankings were created for first and second‐ line treatments recommended for acute mania, acute depression, and maintenance treatment in bipolar I disorder. Created by considering the impact of each treatment across all phases of illness, this hierarchy will further assist clinicians in making evidence‐based treatment decisions. Lithium, quetiapine, divalproex, asenapine, aripiprazole, paliperidone, risperidone, and cariprazine alone or in combination are recommended as first‐line treatments for acute mania. First‐line options for bipolar I depression include quetiapine, lurasidone plus lithium or divalproex, lithium, lamotrigine, lurasidone, or adjunctive lamotrigine. While medications that have been shown to be effective for the acute phase should generally be continued for the maintenance phase in bipolar I disorder, there are some exceptions (such as with antidepressants); and available data suggest that lithium, quetiapine, divalproex, lamotrigine, asenapine, and aripiprazole monotherapy or combination treatments should be considered first‐line for those initiating or switching treatment during the maintenance phase. In addition to addressing issues in bipolar I disorder, these guidelines also provide an overview of, and recommendations for, clinical management of bipolar II disorder, as well as advice on specific populations, such as women at various stages of the reproductive cycle, children and adolescents, and older adults. There are also discussions on the impact of specific psychiatric and medical comorbidities such as substance use, anxiety, and metabolic disorders. Finally, an overview of issues related to safety and monitoring is provided. The CANMAT and ISBD groups hope that these guidelines become a valuable tool for practitioners across the globe.

show abstract

“…Probands often manifest symptoms of BD during adolescence and early adulthood . Longitudinal studies indicate that one of the most robust predictors of subsequent declaration of BD illness is early psychopathology with specific (ie mood symptoms) and/or non‐specific (ie attentional problems) features …”

Section: Introductionmentioning

confidence: 99%

Obesity and frontal‐striatal brain structures in offspring of individuals with bipolar disorder: Results from the global mood and brain science initiative

et al. 2017

View full text Add to dashboard Cite

show abstract

Clinical, Demographic, and Familial Correlates of Bipolar Spectrum Disorders Among Offspring of Parents With Bipolar Disorder

Cited by 27 publications

References 52 publications

Baseline dimensional psychopathology and future mood disorder onset: findings from the Dutch Bipolar Offspring Study

Baseline dimensional psychopathology and future mood disorder onset: findings from the Dutch Bipolar Offspring Study

Canadian Network for Mood and Anxiety Treatments (CANMAT) and International Society for Bipolar Disorders (ISBD) 2018 guidelines for the management of patients with bipolar disorder

Obesity and frontal‐striatal brain structures in offspring of individuals with bipolar disorder: Results from the global mood and brain science initiative

Contact Info

Product

Resources

About