Clinical-diagnostic criteria and peculiarities of treatment of urocystitis in cats

Shulzhenko, N. M.; Chernenko, Oleksandr; Holubyev, O. V.; Bordunova, O. G.; Suslova, N. I.

doi:10.15421/021904

Cited by 4 publications

(1 citation statement)

References 35 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…На теперішній час широко застосовуються лікувально-профілактичні засоби рослинного походження, які впливають на організм комплексно, оскільки до їх складу входять біологічно активні речовини, макро-і мікроелементи, вітаміни (Shulzhenko et al, 2019;Suslova et al, 2018). До таких лікувальнопрофілактичних засобів належать «Кардіофіл» і «Фітохол».…”

Section: днепровский государственный аграрно-экономический университеunclassified

Biochemical indicators of blood of guinea pigs with atherosclerosis against the background of application of herbal preparations “Cardiofil” and “Phytochol”

Antonenko¹,

Agrarian²,

Suslova³

et al. 2019

VTTP

Self Cite

View full text Add to dashboard Cite

show abstract

Section: днепровский государственный аграрно-экономический университеunclassified

Biochemical indicators of blood of guinea pigs with atherosclerosis against the background of application of herbal preparations “Cardiofil” and “Phytochol”

Antonenko¹,

Agrarian²,

Suslova³

et al. 2019

VTTP

Self Cite

View full text Add to dashboard Cite

show abstract

Comparative analysis of etiological factors of infectious urocystitis of dogs and cats

Martyniv,

Kisera,

Gutyj

2024

Regul. Mech. Biosyst.

View full text Add to dashboard Cite

Worldwide, urocystitis is the most common disease of the urinary system. Urocystitis is a generalized name, since the disease has a varied etiology and can be complicated by bacterial microflora, passing from a non-infectious pathological process to an infectious one. Often, during the course of urocystitis, bacteria play the role of a complicating factor or are the primary cause of infectious urocystitis in dogs and cats. It should be noted that various pets can suffer from urocystitis, regardless of their age and sex. Therefore, the study of the causes of the disease among domestic animals, its etiology and degree of spread plays an important role in veterinary science. Identification of pathogens that most often provoke infectious urocystitis with the determination of their sensitivity to antibacterial agents is the key to successful treatment of this disease. Postmortem examination of small animals suffering from bacterial urocystitis showed that the pathological process was present in the urethra and bladder. Pathomorphological changes were characterized by purulent-catarrhal inflammation of the bladder with hemorrhages on its mucous membrane. The wall of the urethra was thickened, the mucous membrane was soaked with diffuse hemorrhages, and urethra was filled with hemorrhagic exudate. In order to find out the percentage ratio of infectious and non-infectious urocystitis, to identify microbial cells, to determine the species composition of the microflora and its sensitivity to antibiotics of different groups, aseptic urine samples were taken from animals with urocystitis. The study was conducted on 82 sick cats and dogs. The percentage of animals studied: 67% were dogs and 33% were cats. Urine collected by cystocentesis was subjected to microscopy and it was sown on nutrient media. Microscopy results showed the presence of bacteria of different shapes and concentrations in the urine of the sick animals. Of all the studied samples, 70.7% had no growth on nutrient media, which indicates the sterility of the studied urine while 29.3% showed bacterial growth when cultured on dense nutrient media (MPA, MPB and blood agar). In the process of microbiological research, the growth of six cultures of microorganisms was revealed, including: Enterococcus spp. (33.3%), Escherichia coli (29.2%), Corynebacterium urealyticum (12.5%), Staphylococcus spp. (12.5%), Proteus spp. (8.3%), Staphylococcus haemolyticus (4.2%). The obtained pure cultures were cultured on the selective Muller-Hinton medium in order to determine their antibiotic resistance. It was established that bacterial agents show the greatest sensitivity to fluoroquinolone antibiotics (enrofloxacin, ofloxacin, ciprofloxacin), cephalosporins (cefazalin, cephalexin, and ceftriaxone) and nitrofuran derivatives (furomag, furagin) on the Muller-Hinton medium.

show abstract

Cardioprotective eﬀ ect of cardiophilic and phytochol preparations under experimental hypothermia hypothermia in rats

Antonenko

Suslova

Семенов

et al. 2019

Nauk. vìsn. vet. med.

View full text Add to dashboard Cite

At present, diseases of the cardiovascular system in small animals range from 15 to 18%. The most common cause of cardiovascular disease in animals is a decrease in myocardial contractile properties. The results of experimental research to study the eﬃ cacy of «Cardiophil» and «Phytochol» for heart disease in rats are presented. Histological examinations prove that cardiac myocytes are killed by ischemia, with subsequent replacement of connective tissue. As a result, not only the damaged area but also a healthy myocardium is involved in the process of cardiac tissue remodeling. Irreversible damage to cardiomyocytes and vascular structures leads to impaired cardiac function, heart failure and the development of arrhythmias. It is established that the use of drugs «Cardiophil» and «Phytochol» promotes the prevention of the above changes, i.e. prevents cardiovascular diseases, in particular myocardium in animals. For the purpose of experimental studies, a control and experimental group of rats 12 months of age and weighing 220g of 5 animals each were formed. All animals were in the same feeding and keeping conditions. The rats of the study group were individually internally given phytopreparations «Cardiophil» 30 min before feeding at a dose of 5 drops, and in an hour «Phytochol» with a small amount of water 3 times a day for 90 days. At day 91 of the experiment, hypothermia was induced in animals as a stress factor, according to the indicated method. Throughout the study, rats were monitored, taking into account the general condition, behavior, response to external stimuli, and the condition of the hair. After 12-14 hours of fasting for 91 days, the animals were removed from the experiment by the conventional method (gas anesthesia). Material was selected and histological examination was performed according to the indicated method. During the whole period of the experimental studies, no deviations from the norm were found in the rats of the control and experimental group: general condition, behavior, rats were mobile, active, adequately responded to external stimuli, readily received feed, and the hair was clean and dry. The histological changes established, in our opinion, may reﬂ ect diﬀ erent phases of the functional activity of the heart, as well as structural alterations and metabolic phenomena that occurred in the tissues of the myocardium and the valve apparatus of rats under the action of a stress factor – a hypothermic state. Experimental studies have shown that the use of phytopreparations «Cardiophil» and «Phytochol» for preventive purposes positively aﬀ ects the function of the cardiovascular system, in particular myocardium, which indicates their cardioprotective eﬀ ect, and accordingly prevent cardiovascular diseases of animals. Key words: cardiovascular diseases, stress, cardioprotective eﬀ ect, myocardium, hypothermia, Cardiophil, Phytochol, rats.

show abstract

Clinical-diagnostic criteria and peculiarities of treatment of urocystitis in cats

Cited by 4 publications

References 35 publications

Biochemical indicators of blood of guinea pigs with atherosclerosis against the background of application of herbal preparations “Cardiofil” and “Phytochol”

Biochemical indicators of blood of guinea pigs with atherosclerosis against the background of application of herbal preparations “Cardiofil” and “Phytochol”

Comparative analysis of etiological factors of infectious urocystitis of dogs and cats

Cardioprotective eﬀ ect of cardiophilic and phytochol preparations under experimental hypothermia hypothermia in rats

Contact Info

Product

Resources

About