Clinical effectiveness of a new collagen-based drug with lincomycin for the prevention and treatment of jaw alveolitis

Abstract

BACKGROUND: Alveolitis is the most common complication that occurs after tooth extraction. Among preventive and therapeutic methods, pharmacological agents for the dry socket treatment have been proposed. However, the gold standard for the prevention and treatment of alveolitis has not been defined.
 AIM: The study aimed to conduct a comparative analysis of the effectiveness of a collagen sponge with lincomycin and an iodoform tampon for the prevention of the development and treatment of alveolitis.
 MATERIAL AND METHODS: The study included 75 patients with jaw alveolitis and patients with teething disorders and chronic periodontitis who underwent planned tooth extraction. The patients were divided into two groups: group 1 underwent a socket revision, whereas group 2 had a tooth extraction. The patients of each group were divided into two subgroups: subgroup A used a collagen sponge with lincomycin and subgroup B used an iodoform tampon. The intensity of pain syndrome, severity of mucosal hyperemia, and collateral edema were assessed, and the epithelialization time of the sockets was recorded.
 RESULTS: The clinical study of the effectiveness of a collagen sponge with lincomycin in comparison with an iodoform tampon demonstrated some advantages of a collagen sponge, including a more comfortable postoperative period, mild pain, less pronounced edema and hyperemia, epithelialization of the extracted teeth sockets 1.5 days earlier.
 CONCLUSION: For the prevention and treatment of alveolitis, especially in patients in whom the use of iodine compounds is contraindicated, the use of Alvanes collagen sponge with lincomycin is preferable to an iodoform tampon.