2018
DOI: 10.12659/msm.909740
|View full text |Cite
|
Sign up to set email alerts
|

Clinical Efficacy of Modified Yanghe Decoction in Ankylosing Spondylitis: A Randomized Controlled Trial

Abstract: BackgroundThis study evaluated the effects of Modified Yanghe Decoction on pain, disease activity, and functional capacity, and its safety in subjects with ankylosing spondylitis (AS).Material/MethodsA randomized, controlled study of subjects with AS was conducted over 8 weeks to compare the efficacy of the Modified Yanghe Decoction to celecoxib-sulfasalazine therapy. Subjects were evaluated at visit 1, and at weeks 4 and 8 of the trial. The Bath ankylosing spondylitis disease activity index (BASDAI), nocturna… Show more

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...
3
2

Citation Types

0
14
0

Year Published

2019
2019
2024
2024

Publication Types

Select...
6

Relationship

0
6

Authors

Journals

citations
Cited by 12 publications
(14 citation statements)
references
References 20 publications
0
14
0
Order By: Relevance
“…As the disease progresses, changes in the vertebrae cause hyperkyphosis and sagittal imbalance, which can lead to restriction of looking straight ahead and a decrease in quality of life. Although there are some conservative treatments available [2,3], the progression of AS is irreversible. Therefore, corrective spinal osteotomy is considered to restore the horizontal visual axis and sagittal balance of the spine in late-stage AS patients.…”
Section: Introductionmentioning
confidence: 99%
“…As the disease progresses, changes in the vertebrae cause hyperkyphosis and sagittal imbalance, which can lead to restriction of looking straight ahead and a decrease in quality of life. Although there are some conservative treatments available [2,3], the progression of AS is irreversible. Therefore, corrective spinal osteotomy is considered to restore the horizontal visual axis and sagittal balance of the spine in late-stage AS patients.…”
Section: Introductionmentioning
confidence: 99%
“…[ 25 ] Due to the safe nature of TCM, contradictions for Yanghe decoction use were not reported in the literature. [ 25 27 ] However, the role of the Yanghe decoction in the treatment of IGM has been overlooked. To the best of our knowledge, this is the first study to evaluate the effects of TCM in the treatment of IGM after surgical excision.…”
Section: Discussionmentioning
confidence: 99%
“…Related research shows that CHM is beneficial to AS, and YHD is one of the representative prescriptions. [ 3 , 18 ] Although previous RCTs have reported the efficacy of YHD in the treatment of AS, the effectiveness of YHD in the treatment of AS still lacks a comprehensive systematic evaluation. The purpose of this meta-analysis is to evaluate the efficacy and safety of YHD in the treatment of AS.…”
Section: Discussionmentioning
confidence: 99%
“…[ 1 , 2 ] According to statistics, the prevalence of AS in China is about 0.3%, and it is more common among young people. [ 3 , 4 ] AS is also one of the main reasons for the labor force loss of young and middle-aged people in China. [ 5 ] Recent studies have shown that the occurrence of this disease is closely related to genetic, immune, environmental, infection, and endocrine factors.…”
Section: Introductionmentioning
confidence: 99%
See 1 more Smart Citation