Clinical, epidemiological, and laboratory characteristics of mild-to-moderate COVID-19 patients in Saudi Arabia: an observational cohort study

Mutair, Abbas Al; Alhumaid, Saad; Alhuqbani, Waad N.; Zaidi, Abdul Rehman Zia; Alkoraisi, Safug; Al-Subaie, Maha F.; AlHindi, Alanoud M.; Abogosh, Ahmed K.; Alrasheed, Aljwhara K.; Alsharafi, Aya A.; Alhuqbani, Mohammed N.; Alhowar, Njoud A.; Salih, Samer; Al-Hedaithy, Mogbil A.; Al‐Tawfiq, Jaffar A.; Al-Shammari, Haifa; Abdulqawi, Rayid; Ismail, Alaa F.; Hamdan, Noura; Saad, Fares; Olhaye, Fahad A.; Eltahir, Tarig A.; Rabaan, Ali A.; Al‐Omari, Awad

doi:10.1186/s40001-020-00462-x

Cited by 67 publications

(70 citation statements)

References 25 publications

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“…The binary logistic regression analysis used in our study quantitatively suggests that the COVID-19 patients who have age > 50 years, who are males, or who have history of HTN and/or DM may have up to 9-fold increased chances of mortality than those patients who are young, who are females and are nondiabetic and normotensive. This is in line with the previous reports that suggest similar correlation between mortality and these factors(2,3,4,5,6,7).…”

supporting

confidence: 93%

WITHDRAWN: Examining and Investigating the Impact of Demographic Characteristics and Chronic Disease with Mortality of COVID-19: Retrospective Study

Mutair¹,

Mutairi

Alhumaid

et al. 2021

Preprint

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Background: The COVID-19 pandemic has burdened hospitals globally and there is currently no proven treatment available. The purpose of the study was to investigate whether demographic characteristics (age and gender) and non-communicable diseases (hypertension and diabetes mellitus) have a significant association with mortality in COVID-19 patients. Methods: This is a retrospective design where we used descriptive and inferential analysis have been employed to analyze the data. Binary logistic regression was done to study the connection between comorbidities and mortality of COVID-19. Results: 43 (86%) of the male patients were non-survivors while 7 (14%) of the female patients were survivors. The odds of non-survivors among hypertensive patients are 3.56 times higher than those who are not having a history of hypertension (HTN). The odds of non-survivors among diabetic patients are 5.17 times higher than those who are not having a history of diabetes (DM). The odds of non-survivors are 2.77 times higher among those who have a history of HTN and DM as compared to those who did not have a history of HTN and DM.Conclusions: Those patients that had a history of hypertension and diabetes had a higher probability of non-survival in contrast to those who did not have a history of diabetes and hypertension. Further studies are required to study the association of comorbidities with COVID-19 and mortality.

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supporting

confidence: 93%

WITHDRAWN: Examining and Investigating the Impact of Demographic Characteristics and Chronic Disease with Mortality of COVID-19: Retrospective Study

Mutair¹,

Mutairi

Alhumaid

et al. 2021

Preprint

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“…And the case fatality rate of COVID-19 is variable [ 7 , 8 ]. The clinical characteristics of the disease in Saudi Arabia is similar to other reported presentations [ [4] , [5] , [6] , 8 , 9 ].…”

Section: Introductionsupporting

confidence: 84%

“…COVID-19had been associated with tremendous medical challenges as well as societal and industrial interruption [ 1 ]. COVID-19 clinical presentation ranges from asymptomatic to severe disease [ [2] , [3] , [4] , [5] , [6] ]. And the case fatality rate of COVID-19 is variable [ 7 , 8 ].…”

Section: Introductionmentioning

confidence: 99%

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and Middle East Respiratory Syndrome Coronavirus (MERS-CoV) coinfection: A unique case series

Elhazmi

Al‐Tawfiq

Sallam

et al. 2021

Travel Medicine and Infectious Disease

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Introduction The emergence of the Severe Acute Respiratory Syndrome Coroanvirus 2 (SARS-CoV-2) had raised possibilities of coinfection with the Middle East Respiratory Syndrome Coronavirus (MERS-CoV) in countries were these two viruses were reported. In this study, we describe the clinical presentation and demographics of eight patients who were coinfected with SARS-CoV-2 and MERS-CoV. Materials and Methods This is a case series of hospitalized patients admitted to Saudi intensive care units (ICUs). We collected demographics, underlying conditions, presenting symptoms and clinical outcome from the patients’ medical records. Results During the study period from March 14, 2020 to October 19, 2020, there was a total of 67 SARS-CoV-2 ICU admitted patients who underwent simultaneous SARS-CoV-2 and MERS-CoV testing. Of those patients, 8 (12%) tested positive for both SARS-CoV-2 and MERS-CoV. There were 6 (75%) males, the mean age + SD was 44.4 + 11.8 years, and 7 (87.5%) were obese. Of the patients, 7 (87.5%) were non-smokers, 1 (12.5%) had diabetes mellitus, 1 (12.5%) had heart failure, and 1 (12.5%) had been on anti-platelet therapy. The mean hospital length of stay (LOS) was 21.1 + 11.6 days and the average ICU LOS was 10.9 + 6.03 days. All patients received supportive therapy and all were treated with corticosteroid. Of all the patients, 4 (50%) were discharged home and 3 (37.5%) died. Conclusion This case series is an important addition to the medical knowledge as it showed the interaction of the coinfection of SARS-CoV-2 and MERS-CoV.

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“…COVID-19 has a spectrum of presentations from asymptomatic cases to severe disease requiring intensive care unit admission [ 6 , [21] , [22] , [23] ]. The current study showed that 59% of the patients included in the home monitoring program were asymptomatic.…”

Section: Discussionmentioning

confidence: 99%

COVID-19 home monitoring program: Healthcare innovation in developing, maintaining, and impacting the outcome of SARS-CoV-2 infected patients

Al‐Tawfiq

Kheir

Al-Dakheel

et al. 2021

Travel Medicine and Infectious Disease

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Introduction The Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) had caused an increased burden on healthcare organizations. Thus, a new strategy is needed to ensure all COVID-19 positive cases are followed up appropriately, receive the proper medical and psychological support, and comply with the isolation guidelines. Here, we describe the characteristics and outcome of COVID-19 patients who were managed at home. In addition, we describe the differences between asymptomatic and those with mild symptoms. Materials and Methods This is descriptive study of all COVID-19 positive cases who were monitored utilizing the home care concept. Results During the study period from June 8 to October 18, 2020, there were a total of 5368 COVID-19 patients who were referred to the home isolation/monitoring program. Of those, 2397 (45%) were female and 2971 (55%) were male. Of the total cases, 295 (5%) required hospital admission, 45 (1%) were admitted to zone 2, and the majority 5028 (94%) were continued in the home monitoring till recovery. Of the total cases, 3137 (59%) were asymptomatic and the remaining 41% were symptomatic. Asymptomatic patients in comparison to symptomatic patients showed significant differences in relation to age, gender, being healthcare workers, and the presence of significant medical conditions. However, a logistic regression analysis showed that only age and the presence of diabetes mellitus were associated with the presence of symptoms. The mean age ( + SD) of those who required hospital admission was higher than those who were discharged or cared for in zone 2. Conclusion The utilization of home monitoring program was effective and safe in patients who were either asymptomatic or had mild symptoms.

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Clinical, epidemiological, and laboratory characteristics of mild-to-moderate COVID-19 patients in Saudi Arabia: an observational cohort study

Cited by 67 publications

References 25 publications

WITHDRAWN: Examining and Investigating the Impact of Demographic Characteristics and Chronic Disease with Mortality of COVID-19: Retrospective Study

WITHDRAWN: Examining and Investigating the Impact of Demographic Characteristics and Chronic Disease with Mortality of COVID-19: Retrospective Study

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and Middle East Respiratory Syndrome Coronavirus (MERS-CoV) coinfection: A unique case series

COVID-19 home monitoring program: Healthcare innovation in developing, maintaining, and impacting the outcome of SARS-CoV-2 infected patients

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