Clinical evaluation of neodymium-iron-boron (Ne2Fe14B) rare earth magnets in the treatment of mid line diastemas

Mandava, Prasad; Manoj-Kumar, Mitta; Singaraju, Gowri Sankar; Chaitanya, Nellore; Ganugapanta, Vivek Reddy; Nettam, Venkatesh

doi:10.4317/jced.52352

Cited by 12 publications

(22 citation statements)

References 19 publications

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“…Following deflation and removal of the tamps, polymethylmethacrylate (PMMA) cement mixed with neodymium-iron-boron (NdFeB) magnets were implanted into the thoracic vertebral body. Gas ethylene oxide sterilized NdFeB magnets were used, as they are known to be biocompatible [ 21 ]. As an internal control, PMMA without magnets was placed two vertebrae levels below the magnet enhanced kyphoplasty.…”

Section: Resultsmentioning

confidence: 99%

Magnetic kyphoplasty: A novel drug delivery system for the spinal column

et al. 2018

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Vertebral compression fractures (VCFs) caused by metastatic malignancies or osteoporosis are devastating injuries with debilitating outcomes for patients. Minimally invasive kyphoplasty is a common procedure used for symptomatic amelioration. However, it fails in treating the underlying etiologies of VCFs. Use of systemic therapy is limited due to low perfusion to the spinal column and systemic toxicity. Localized delivery of drugs to the vertebral column can provide a promising alternative approach. A porcine kyphoplasty model was developed to study the magnetically guided drug delivery of systemically injected magnetic nanoparticles (MNPs). Jamshidi cannulated pedicle needles were placed into the thoracic vertebra and, following inflatable bone tamp expansion, magnetic bone cement was injected to the vertebral body. Histological analysis was performed after intravenous injection of MNPs. Qualitative analysis of harvested tissues revealed successful placement of magnetic cement into the vertebral body. Further quantitative analysis of histological sections of several vertebral bodies demonstrated enhanced accumulation of MNPs to regions that had magnetic cement injected during kyphoplasty compared to those that did not. By modifying the kyphoplasty bone cement to include magnets, thereby providing a guidance stimulus and a localizer, we were successfully able to guide intravenously injected magnetic nanoparticles to the thoracic vertebra. These results demonstrate an in-vivo proof of concept of a novel drug delivery strategy that has the potential to treat the underlying causes of VCFs, in addition to providing symptomatic support.

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Section: Resultsmentioning

confidence: 99%

Magnetic kyphoplasty: A novel drug delivery system for the spinal column

et al. 2018

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“…This treatment is long and requires careful observance of oral hygiene. However, there is another way to correct orthodontic pathologies -the use of devices with magnets [3,4]. Such devices have several advantages: mechanical transfer of force without friction; predictable magnitude of force; high stability of parameters of modern magnetic materials; easier tooth brushing due to a significant simplification of the device design [5].…”

Section: Introductionmentioning

confidence: 99%

ORTHODONTIC TREATMENT WITH Nd-Fe-B MAGNETS

Kutsevlyak

Стариков

Samofalov

et al. 2020

EUREKA: Health Sciences

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The aim. The development of methodology for experimental and theoretical assessment of interaction forces between magnets in an orthodontic apparatus, the test of corrosion resistance of protective oxide and nitride coatings deposited on Nd-Fe-B magnets surface. Materials and methods. The Nd-Fe-B permanent magnets with saturation magnetization Ms≈1100 G and bilayer ZrN / ZrO2 coatings were used. To experimental measure of interaction forces between magnets the device was assembled on the base of analytical balance. The distance between the magnets was varied using non-magnetic plates. The ZrO2 and ZrN coatings have been analyzed for their corrosion properties in 0.9 % NaCl quasi-physiological solution. Results. An original method was proposed for calculating of magnetic interaction forces for materials with high magnetic anisotropy, which has good agreement with experimental measurement of forces. The theoretical model takes into account the size of the magnets and the mutual influence of their opposite faces. An increase of corrosion resistance of magnetic materials can be provided by zirconium oxide or nitride compounds, which contribute to inhibition of electrochemical corrosion of Nd-Fe-B magnets. Conclusions. A method for calculating of interaction forces between permanent magnets, which are used for correction of malocclusion in orthodontic, has been developed. The passivation of the Nd-Fe-B permanent magnets surface can be achieved by applying of bilayer ZrN / ZrO2 coating.

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“…These properties allowed for the production of small magnets. Nd-Fe-B magnets are less costly to produce than Sm-Co alloys, and are the most common rare earth permanent magnet in use today (3)(4)(5)(6).…”

Section: Introductionmentioning

confidence: 99%

“…Magnets have many advantages for orthodontic applications (1,4,7,8). Magnets does not decrease orthodontic force during tooth movement.…”

Section: Introductionmentioning

confidence: 99%

“…The first report of the use of magnetic force to move teeth was in 1977 when Kawata and Takeda (11) described a technique of using magnetic brackets of Co-Cr-Fe alloy, bonded to the upper anterior and the lower anterior teeth, for the closure of interdental spaces (1,3,4). Prasad et al reported that Nd-Fe-B magnets were used for diastema closure in a clinical study (4) and there are many other studies and clinical reports using Nd-Fe-B magnets in orthodontic treatment, such as for forced eruption of impacted teeth (4,5,8,10,(12)(13)(14). From an esthetic standpoint, magnets may not be ideal due to the black or metallic color.…”

Section: Introductionmentioning

confidence: 99%

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Effect of magnet position on tipping and bodily tooth movement in magnetic force-driven orthodontics

Ishida

Kuwajima

Lee

et al. 2019

Preprint

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Magnets have many advantages for orthodontic applications. The purpose of this study was to investigate the effect of the magnet position on the tipping and bodily tooth movement using 3D digital analysis ex vivo. Orthodontic typodont models for space-closing (2mm diastema) were created, mimicking maxillary central incisors. Tooth models (10mm crown and 14mm root length) created by 3D printer were used for the typodont model. Nd-Fe-B magnets were placed in the middle of the tooth (Model-M) and the cervical area (Model-C). The typodonts were immersed in a hot water-bath at 55℃ to initiate tooth movement. The scanned typodont data before and after tooth movement were superimposed, and 3D coordinates (X, Y, Z) on the tooth were obtained. The root apex data was also obtained by superimposing the designed tooth model on the crown portion of the typodont model. 3D movement of the crown and the root apex, moving speed, degree of rotation (yaw, pitch, and roll) in 2 models were analyzed and compared by Pearson’s correlation confidents. Moderate crowding typodont cases were treated with two magnet position settings, and patterns of tooth/root movement and rotation were compared. The largest movement was observed in the X-axis as intended. Model-M indicated higher moving speed and more tooth rotation than Model-C. In Model-M, the root apex moved to the opposite direction of the crown movement with a negative correlation. In contrast, the crown and root apex moved in the same direction with a positive correlation in Model-C. In the ex vivo moderate crowding case, Model-C created bodily movement, in which the cusp and root apex both moved in the same direction with less tooth rotation. The results of this study validated that modifying the position of the applied magnetic force was able to increase the amount of bodily tooth movement and decrease unwanted rotation/tipping in an ex vivo setting.

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Clinical evaluation of neodymium-iron-boron (Ne2Fe14B) rare earth magnets in the treatment of mid line diastemas

Cited by 12 publications

References 19 publications

Magnetic kyphoplasty: A novel drug delivery system for the spinal column

Magnetic kyphoplasty: A novel drug delivery system for the spinal column

ORTHODONTIC TREATMENT WITH Nd-Fe-B MAGNETS

Effect of magnet position on tipping and bodily tooth movement in magnetic force-driven orthodontics

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