Clinical evaluation of sodium hyaluronate in the treatment of patients with sopraspinatus tendinosis under echographic guide: Experimental study of periarticular injections

Meloni, Francesco; Milia, F.; Cavazzuti, Milena; Doria, Carlo; Lisai, P.; Profili, Stefano; Meloni, Giovanni Battista

doi:10.1016/j.ejrad.2007.11.001

Cited by 57 publications

(75 citation statements)

References 15 publications

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“…The mean age of patients managed was 59.2 years. The numbers of injections varied: 2 in 1 studies 29 , 1 a week for five weeks in 5 studies [19][20][21]24,25 , one 23,28 © C I C E d i z i o n i I n t e r n a z i o n a l i studies and 3 22,24,26,27 in 4 studies. Intra-articular injection were undertaken in 5 studies 19,20,22,24,27 subacromial injections under US guidance were administered in seven studies 19,21,23,25,26,28,29 .…”

Section: Resultsmentioning

confidence: 99%

“…In particular, Byun 23 showed better results in terms of ROM, proving that HA may improve motion and function of the shoulder, especially in active internal rotation. Four studies 21,[24][25][26] comparing patients undergoing HA vs phosphate-buffered saline injections reported good clinical results and pain relief. In particular, Blaine 24 showed better ROM recovery, reduced pain at night, and significantly higher overall satisfaction in the HA group; Meloni 21 showed a significant difference in the improvement of clinical symptoms and recovery of functional status in patients at 1 month after the end of the HA infiltrative cycle, in particular HA group VAS score was 2.8 respect 8.0 in the sodium chloride solution group.…”

Section: Discussionmentioning

confidence: 99%

“…Four studies 21,[24][25][26] comparing patients undergoing HA vs phosphate-buffered saline injections reported good clinical results and pain relief. In particular, Blaine 24 showed better ROM recovery, reduced pain at night, and significantly higher overall satisfaction in the HA group; Meloni 21 showed a significant difference in the improvement of clinical symptoms and recovery of functional status in patients at 1 month after the end of the HA infiltrative cycle, in particular HA group VAS score was 2.8 respect 8.0 in the sodium chloride solution group. Chou 25 and Moghtaderi showed a significantly improvement in Constant score and VAS scores at 12 weeks and 6 weeks, respectively.…”

Section: Discussionmentioning

confidence: 99%

“…Intra-articular injection were undertaken in 5 studies 19,20,22,24,27 subacromial injections under US guidance were administered in seven studies 19,21,23,25,26,28,29 . The diagnosis of rotaror cuff tear was mainly on clinical examination, and confirmed at MRI or US scans.…”

Section: © C I C E D I Z I O N I I N T E R N a Z I O N A L Imentioning

confidence: 99%

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Clinical evidence in the treatment of rotator cuff tears with hyaluronic acid

Osti

Buda

Buono

et al. 2015

MLTJ

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VAS and functional score in all trials that we have analyzed. Conclusion: intra-articular injection with HA is effective in reducing pain and improving function in shoulder with rotator cuff tears and without severe adverse reaction. Level of evidence: Level I.KEY WORDS: cuff tears, glenohumeral, hyaluronic acid, hyaluronate, shoulder, viscosupplementation. IntroductionRotator cuff pathology is the main cause of shoulder pain and disability. The causes arises from a multivariate etiology, often due to age-related chronic degeneration in which play a role the decrease in collagen synthesis, increase in free radicals expression and metabolism imbalance in favor of catabolic activity 1 . Classically, the diagnosis is clinical, characterized by pain, mostly during the night, severe disability and functional impairment 2,3 . MRI and US may usefully this diagnosis 4,5 . The first management is conservative, including oral anti-inflammatory drugs, topic agents, cortisone injections, physical therapies, and joint rehabilitation exercises [6][7][8] . In the past, much has been published on the use of steroid and local anesthetic injections, administered alone or in combination to other therapies. On the other hand, many evidences have corroborated their potential effects as negative on the collagen matrix of tendons and ligaments [9][10][11][12][13][14] . In the substance, compared to other treatments, effective in the mid and long term, the benefits after these injections could be valid only in the short-term 15 . Clinical trials have confirmed that HA may be effective for management of tendons disorders. Specifically, in Achilles tendinopathy, the tendon healing process is improved and the formation of adhesions in reduces by the regulation of the expression of vascular endothelial growth factor (VEGF) and type IV collagen 16 . After hand surgery, it improves the motion of fingers lubricating the tendon surface and reducing friction and adhesions 17,18 . Few papers have investigated the effects of HA in rotator cuff disorders, and no systematic review have been performed on this matter. The aim of the present review is to summarize all papers published inherently to the injection of HA for management of cuff tendinopathy, in terms of feasibility, safety, and efficacy. © C I C E d i z i o n i I n t e r n a z i o n a l i Material and methods Criteria for considerationWe included randomized clinical trials, prospective and retrospective studies reporting on clinical and functional outcomes in patients who had undergone sub-acromial or intra-articular injections of HA for management of rotator cuff pathology. Given the linguistic capabilities of the research team, we considered only papers published in English language. We performed a broad search for relevant studies published up to August 2014 in Medline (http://www.ncbi.nlm.nih.gov/sites/entrez/); Ovid (http://www.ovid.com); Cochrane Reviews (http://www.cochrane.org/reviews/), Google Scholar, Enbase database. Combined key words for the search were "cuff tears", "gl...

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Section: Resultsmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: © C I C E D I Z I O N I I N T E R N a Z I O N A L Imentioning

confidence: 99%

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Clinical evidence in the treatment of rotator cuff tears with hyaluronic acid

Osti

Buda

Buono

et al. 2015

MLTJ

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“…Recent findings demonstrate that corticoid injection are worse than most conservative interventions in the long-term 15 they could weak tendon structure enhancing the risk of tendon rupture 16 . Several studies have shown that peritendinous application of hyaluronic acid (HA) is an effective therapeutic option for the treatment of chronic tendinopathy 17,18 . Hyaluronic acid (HA) is one of the main components of synovial fluid, which is produced in the normal tendon sheath and it is a main component of tendon extracellular matrix 19 .…”

Section: Introductionmentioning

confidence: 99%

Efficacy and safety of hyaluronic acid (500-730kDa) Ultrasound-guided injections on painful tendinopathies: a prospective, open label, clinical study

Fogli

Giordan

Mazzoni

2017

MLTJ

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Therapeutic effects of hyaluronate injections in patients with chronic painful shoulder: A meta‐analysis of randomized controlled trials

Saito¹,

Furuya²,

Kotake³

2010

Arthritis Care & Research

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Objective. To elucidate the therapeutic efficacy and safety of injection of hyaluronate (HA) for chronic painful shoulder. Methods. The meta-analysis comprised randomized controlled trials (RCTs) that compared the efficacy of HA injections with that of a placebo. Articles were retrieved through systematic searches of databases, including Medline, EMBase, and Japana Centra Revuo Medicina. The outcome end points were classified into 5 categories: pain, shoulder range of motion (ROM), total functional score, comparison between HA and steroid injections, and HA safety. The primary outcome measures of the efficacy of HA injections were the standardized mean differences (SMDs) and the relative risk (RR) or odds ratio (OR) between HA and placebo groups. Conclusion. This meta-analysis confirms that HA injection is effective in relief of pain and is a safe alternative therapy for chronic painful shoulder.

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Clinical evaluation of sodium hyaluronate in the treatment of patients with sopraspinatus tendinosis under echographic guide: Experimental study of periarticular injections

Cited by 57 publications

References 15 publications

Clinical evidence in the treatment of rotator cuff tears with hyaluronic acid

Clinical evidence in the treatment of rotator cuff tears with hyaluronic acid

Efficacy and safety of hyaluronic acid (500-730kDa) Ultrasound-guided injections on painful tendinopathies: a prospective, open label, clinical study

Therapeutic effects of hyaluronate injections in patients with chronic painful shoulder: A meta‐analysis of randomized controlled trials

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