Clinical Evidence on the Purported Pharmacokinetic Interactions between Corticosteroids and Mycophenolic Acid

Rong, Yan; Kiang, Tony K. L.

doi:10.1007/s40262-023-01212-y

Clin Pharmacokinet

2023

DOI: 10.1007/s40262-023-01212-y

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Clinical Evidence on the Purported Pharmacokinetic Interactions between Corticosteroids and Mycophenolic Acid

Yan Rong

Tony K. L. Kiang

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2024

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Cited by 1 publication

References 77 publications

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Approaches Towards Better Immunosuppressive Agents

Walczak,

Iwaszkiewicz-Grześ,

Cholewiński

2024

CTMC

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Several classes of compounds are applied in clinics due to their immunosuppressive properties in transplantology and the treatment of autoimmune diseases. Derivatives of mycophe-nolic acid, corticosteroids and chemotherapeutics bearing heterocyclic moieties like methotrexate, azathioprine, mizoribine, and ruxolitinib are active substances with investigated mechanisms of action. However, improved synthetic approaches of known drugs and novel derivatives are still being reported to attempt better accessibility and therapeutic properties. In this review article, we present the synthesis of the designed chemical structures based on recent literature reports con-cerning novel compounds as promising immunosuppressive drugs. Moreover, some of the dis-cussed derivers revealed also other types of activities with prospective medicinal potential.

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Approaches Towards Better Immunosuppressive Agents

Walczak,

Iwaszkiewicz-Grześ,

Cholewiński

2024

CTMC

View full text Add to dashboard Cite

show abstract

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Clinical Evidence on the Purported Pharmacokinetic Interactions between Corticosteroids and Mycophenolic Acid

Cited by 1 publication

References 77 publications

Approaches Towards Better Immunosuppressive Agents

Approaches Towards Better Immunosuppressive Agents

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