Clinical features and predictive factors in psoriatic arthritis–related uveitis

Queiró, Rubén; Torre, Juan Carlos Gómez de la; Belzunegui, Joaquín; González, Carlos; Dios, J. R. De; Unanue, Francisco; Figueroa, Manuel

doi:10.1053/sarh.2002.28798

Cited by 72 publications

(36 citation statements)

References 16 publications

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“…Thus, anterior uveitis frequently appears as the first indication of the concomitant presence of extra-ocular diseases, ankylosing spondylitis being the most common of them. Queiro et al (2002) considered the HLA-DR13 antigen and extensive axial involvement in joint diseases to be the best predictors of anterior uveitis [39].…”

Section: Bacterial Infectionsmentioning

confidence: 99%

Immunogenetics and infectious diseases: special reference to the mayor histocompatibility complex

Alves¹,

Souza²,

Meyer³

et al. 2006

Braz J Infect Dis

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Many studies have tried to identify genetic markers for infectious diseases, some of them have focused on human leukocyte antigens (HLA). The products of HLA genes interact with surfacespecific receptors of T lymphocytes, resulting in activation of the host's immune response. Association of bacterial, viral, parasitic and fungal infections with the host's HLA has been widely investigated. The type and strength of this association differs among distinct populations, as well as among racial and/or ethnic groups. The new molecular methods for the identification of the HLA alleles, and the resulting new nomenclature, have contributed to a better understanding of this system. Unfortunately, this information has not been adequately transmitted to clinicians, which hampers the understanding of the association between the HLA system and diseases. We revised relevant studies on the association of HLA genes with infectious diseases, demonstrating their importance in the pathogenic mechanisms, through increased susceptibility or protection against infections and their complications.

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Section: Bacterial Infectionsmentioning

confidence: 99%

Immunogenetics and infectious diseases: special reference to the mayor histocompatibility complex

Alves¹,

Souza²,

Meyer³

et al. 2006

Braz J Infect Dis

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“…Extraarticular manifestations of PsA include conjunctivitis or iritis (in 7–33% of patients) and aortic incompetence (in <4% of patients), which may occur late during the course of PsA [6,7,8]. The pathogenesis of PsA is unknown, but genetic predisposition as well as environmental and immunologic factors contribute to the determination of disease susceptibility.…”

Section: Introductionmentioning

confidence: 99%

Role of Contrast-Enhanced Ultrasound in Early Diagnosis of Psoriatic Arthritis

et al. 2009

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Background: Radiographic examination (Rx) is still the best method to obtain an accurate diagnosis of psoriatic arthritis (PsA). Nevertheless, ultrasound (US) examination of the potentially involved joints has started to play a leading role. The sensitivity and specificity of a scan can be determined by contrast enhancement in the diagnosis of arthritis during PsA in comparison with basal US with MRI. Methods: Our study was made on 22 uninformed patients showing clinical suspicion of PsA. The patients were submitted to clinical evaluation, Rx, US with and without contrast enhancement and MRI. The parameters evaluated by basal US were effusion, synovial hypertrophy, positiveness to color power Doppler signals and bone erosion. Results: Contrast-enhanced US (CEUS) seems to amplify small alterations previously detected by US and, moreover, increases the diagnostic confidence in cases of suspected symptomatology with a negative diagnosis. Finally, CEUS appears to have a concordance of almost 100% with the results of MRI with contrast enhancement. Conclusion: US appears to be an effective method for detecting the alterations in bone outline and soft tissues, such as synovitis. Furthermore, US provides useful information concerning the evolution of vascularization and the dynamic behavior of tendons.

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“…In addition, a negative test for HLA-B27 was a prognostic factor for the presence of anterior uveitis and axial involvement in several follow-up reports that focused on AS patients. [13][14][15] Zeboulon et al [11] also reported that the prevalence of uveitis ranged from 40-48% in patients with HLA-B27-positive SpA but only 15-25% in HLA-B27-negative patients. Although the possibility of sarcoidosis-related uveitis can not be ruled out in our case, we considered the diagnosis of uSpA to be more likely due to the patient's rapid recovery from non-granulomatous eye lesions combined with his inflammatory low back pain.…”

Section: Discussionmentioning

confidence: 99%

Early Undifferentiated Spondyloarthropathy in a Patient with Sarcoidosis

Kara¹,

Özçakar²,

Kalyoncu

et al. 2013

Turk J Rheumatol

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Bu yazıda, sarkoidoz remisyonunda iken inflamatuvar bel ağrısı ve üveit ile başvuran 49 yaşında bir erkek olgu sunuldu. Diferansiye olmamış spondiloartropati ve sarkoidoz birlikteliği, muhtemel etyolojik ilişki göz önünde bulundurularak, tanı ve tedavideki mevcut zorluklar eşliğinde irdelendi.Anahtar sözcükler: İnflamatuvar bel ağrısı; sarkoidoz; spondiloartropati; üveit.In this article, we present a 49-year-old male case who was admitted with inflammatory back pain and uveitis when he was in remission for sarcoidosis. The concomitance of undifferentiated spondyloarthropathy and sarcoidosis with an emphasis on their possible etiological association was also discussed in the light of current diagnostic and therapeutic challenges.

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Clinical features and predictive factors in psoriatic arthritis–related uveitis

Cited by 72 publications

References 16 publications

Immunogenetics and infectious diseases: special reference to the mayor histocompatibility complex

Immunogenetics and infectious diseases: special reference to the mayor histocompatibility complex

Role of Contrast-Enhanced Ultrasound in Early Diagnosis of Psoriatic Arthritis

Early Undifferentiated Spondyloarthropathy in a Patient with Sarcoidosis

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