Clinical features of allergic rhinitis in Korean children

Kim, Jae Sook; Kang, Hee Suk; Jang, Hae Ji; Kim, Jeong Hee; Lim, Dae Hyun; Son, Byong Kwan

doi:10.4168/aard.2015.3.2.116

Cited by 13 publications

(4 citation statements)

References 28 publications

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“…A Norwegian study reported a 72.8% prevalence of AR and 27.2% of NAR in 10 year-olds 7. A Korean study reported 76.9% AR vs 23.1% NAR 21. The prevalence reported in our study may be different those in from other studies due to not having inhalant allergen test data from all patients, particularly ≤5 years old.…”

Section: Discussioncontrasting

confidence: 81%

See 1 more Smart Citation

Comorbidities and Phenotypes of Rhinitis in Korean Children and Adolescents: A Cross-sectional, Multicenter Study

Lee

Yum

Sheen

et al. 2017

Allergy Asthma Immunol Res

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PurposeRhinitis is a nasal inflammatory disease in children and adolescents. However, little is known about the phenotypes and characteristics of allergic rhinitis (AR) in Korean children and adolescents. The objective of this study was to analyze the symptoms and comorbidities of rhinitis, to compare AR to non-allergic rhinitis (NAR), and to reveal the phenotypes and features of AR in a Korean pediatric population.MethodsPatients under 18 years of age with rhinitis symptoms were recruited from January 2013 to January 2015 by pediatric allergists. We analyzed symptoms, phenotypes, comorbidities, and allergen sensitization in this cross-sectional, multicenter study.ResultsMedical records were collected from 11 hospitals. The AR group has 641 (68.3%) patients, with 63.2% of boys and 7.5 (±3.4) years of mean age. The NAR group has 136 (14.5%) patients, with 55.1% of boys and 5.5 (±2.9) years of mean age. Moderate-severe persistent AR affected 41.2% of AR patients. Nasal obstruction was more common in NAR patients (P<0.050), whereas AR patients sneezed more (P<0.050) and more commonly had conjunctivitis, asthma, and otitis media (P<0.050). Sinusitis was the most common comorbidity in both groups. Allergen sensitization was caused by house dust mites (HDMs) (90.2%), pollen (38.7%), and animal dander (24.8%) in AR patients. Pollen and animal dander sensitization significantly increased age-dependently (P<0.050), but 91.9% of AR patients were already sensitized to HDMs before 5 years old.ConclusionsOur study revealed that AR was more prevalent than NAR and that 41.2% of AR presented with moderate-severe disease in Korean pediatric populations. Sinusitis was the most common comorbidity, and sleep disturbance was associated with the severity of rhinitis. The majority of AR patients were sensitized to HDMs in preschool ages. Further studies, including nationwide and longitudinal data, will help understand the relationship between these diseases.

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Section: Discussioncontrasting

confidence: 81%

“…Sensitization rates to pollen or animal dander increased significantly with advancing age. The prevalence and changing patterns of allergen sensitization in our study are similar to those in other Korean studies 21. Although sensitization to pollen is reported to be related to AR, we did not confirm this finding in our study 3738…”

Section: Discussionsupporting

confidence: 61%

Comorbidities and Phenotypes of Rhinitis in Korean Children and Adolescents: A Cross-sectional, Multicenter Study

Lee

Yum

Sheen

et al. 2017

Allergy Asthma Immunol Res

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“…Crameri define el ImmunoCAP como la técnica gold standard de diagnóstico in vitro [27], a la espera de nueva evidencia científica respecto al resto de técnicas. Por otro lado, es la técnica de referencia con la que se comparan las demás en los estudios de correlación [28][29][30].…”

Section: Sistemas Multiplexunclassified

Proyecto VALIDA: Validation of ALlergy In vitro Diagnostics Assays (Herramientas y recomendaciones para la valoración de las pruebas in vitro en el diagnóstico de la alergia)

Casas

Esteban

González‐Muñoz

et al. 2020

Advances in Laboratory Medicine / Avances en Medicina De Laboratorio

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ResumenEn la evaluación del paciente con sospecha de alergia las pruebas de detección y cuantificación de la inmunoglobulina E (IgE) específica in vitro se usan de manera habitual en los laboratorios clínicos para ayudar en el diagnóstico de la alergia. Actualmente existen diferentes alternativas comerciales para realizar estos ensayos, pero los resultados obtenidos por cada uno de ellos pueden variar, lo que condiciona el diagnóstico y el tratamiento que se le proporcionará al paciente. Con el fin de dar respuesta a los retos planteados por las diferencias entre las distintas técnicas para la determinación in vitro de la IgE específica, un grupo de expertos ha recogido en un documento una serie de recomendaciones sobre las implicaciones que puede tener el uso de una determinada técnica in vitro y el impacto en el manejo del paciente alérgico que suponen las diferencias entre las distintas técnicas. La lectura y el análisis de este documento de consenso ayudarán a entender las implicaciones que tiene el cambio de método de diagnóstico in vitro en el manejo del paciente con alergia, en su calidad de vida y en los costes socioeconómicos asociados a la enfermedad.

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“…Chronic rhinitis affects about 30% population worldwide [1]. Allergic rhinitis is one of the most common phenotypes of this disease and one of the most prevalent allergic diseases worldwide [1][2][3][4]. Diagnosis of allergic rhinitis is based on typical clinical signs (rhinorrhea, nasal obstruction or blockage, nasal itching, sneezing, and postnasal drip) and positive results of allergic tests [4].…”

Section: Introductionmentioning

confidence: 99%

Translation, adaption and validation of the total nasal symptom score (TNSS) for Lithuanian population

Tamašauskienė

Gasiūnienė

Šitkauskienė

2021

Health Qual Life Outcomes

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Background Allergic rhinitis is one of the most prevalent allergic diseases worldwide which diagnosis is based on typical clinical signs and positive results of allergic tests. Selection and evaluation of treatment is based mainly on subjective symptoms. Objective measurement of patients’ complaints is necessary for proper documentation and follow-up. There are no short simple validated questionnaire assessing nasal symptoms in patients with allergic rhinitis in Lithuania. Total nasal symptoms score (TNSS) is a brief questionnaire which evaluate the severity of main symptoms of allergic rhinitis widely used in different countries. Our aim was to translate the TNSS in the Lithuanian language and to validate it. Methods Prospective cross-cultural adaption and validation study was performed. Linguistic validation of TNSS was performed and validity and reliability were assessed. Patients with chronic allergic and non-allergic rhinitis and healthy individuals were included in this study. Patients had to complete translated version of TNSS. Patients with allergic rhinitis additionally were asked to fill Rhinoconjunctivitis Quality of Life Questionnaire (RQLQ). Results Seventy-six individuals were involved into the study: 16 with non-allergic rhinitis (NAR) (21.1%), 49 with allergic rhinitis (AR) (64.5%) and 11 healthy individuals (14.5%). Cronbach’s α was 0.87. TNSS score was significantly higher in patients with NAR and AR compared with healthy individuals (3.56 ± 2.28 vs. 4.28 ± 2.46 vs. 0.27 ± 0.91). Positive significant correlation was found between TNSS score and RQLQ score (rs = 0.77, p < 0.01). Conclusions The Lithuanian version of the TNSS proved to be a valid instrument for assessing nasal symptoms in patients with allergic rhinitis.

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Clinical features of allergic rhinitis in Korean children

Cited by 13 publications

References 28 publications

Comorbidities and Phenotypes of Rhinitis in Korean Children and Adolescents: A Cross-sectional, Multicenter Study

Comorbidities and Phenotypes of Rhinitis in Korean Children and Adolescents: A Cross-sectional, Multicenter Study

Proyecto VALIDA: Validation of ALlergy In vitro Diagnostics Assays (Herramientas y recomendaciones para la valoración de las pruebas in vitro en el diagnóstico de la alergia)

Translation, adaption and validation of the total nasal symptom score (TNSS) for Lithuanian population

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