Clinical features of depressive episode with onset in adolescence and the risk of bipolar depression

Beglyankin, N. I.; Burygina, L. A.; Levin, Morris; Bardenshteyn, Leonid M.

doi:10.17116/jnevro20191191222

Z. nevrol. psikhiatr. im. S.S. Korsakova

2019

DOI: 10.17116/jnevro20191191222

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Clinical features of depressive episode with onset in adolescence and the risk of bipolar depression

N. I. Beglyankin

L. A. Burygina²,

Morris Levin³

et al.

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Cited by 2 publications

References 19 publications

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Probabilistic diagnosis of bipolar affective disorder: possibilities and limitations (literature review)

Simutkin

2024

V.M. BEKHTEREV REVIEW OF PSYCHIATRY AND MEDICAL PSYCHOLOGY

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The literature review presents the main modern data on the epidemiology and socio-economic significance of bipolar affective disorder (BD), discusses the difficulties of early diagnosis of bipolar spectrum disorders, predictors of the bipolar course of affective disorders and a probabilistic approach to the diagnosis of BD, discusses controversial issues in the diagnosis of mixed affective states, the use of potential biomarkers both for the diagnosis of bipolar disorder and for the differential diagnosis of unipolar and bipolar depression, as well as possible therapeutic approaches for the probabilistic diagnosis of bipolar disorder.

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Probabilistic diagnosis of bipolar affective disorder: possibilities and limitations (literature review)

Simutkin

2024

V.M. BEKHTEREV REVIEW OF PSYCHIATRY AND MEDICAL PSYCHOLOGY

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The Association Between Suicide Attempts, Anxiety, and Childhood Maltreatment Among Adolescents and Young Adults With First Depressive Episodes

Chen

Cao

et al. 2021

Front. Psychiatry

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Objective: Adolescents and young adults are susceptible to high-risk behaviors such as self-harm and suicide. However, the impact of childhood maltreatment on suicide attempts in adolescents and young adults with first episode of depression remains unclear. This study examined the association between suicide attempts and childhood maltreatment among adolescents and young adults with first depressive episodes.Methods: A total of 181 adolescents and young adults with first depressive episodes were included. The Child Trauma Questionnaire (CTQ), Beck Anxiety Inventory (BAI), and Patient Health Questionnaire-2 (PHQ-2) were used to assess childhood maltreatment and the severity of anxiety and depressive symptoms, respectively. The suicide item in the MINI-International Neuropsychiatric Interview (M.I.N.I.) 5.0 was used to assess the suicide attempts. Logistic regression analyses were used to explore the associated factors of suicide attempts.Results: The prevalence of SA in the total sample was 31.5% (95% CI = 24.9–38.1%). Multivariate logistic regression analyses revealed that the diagnosis of bipolar disorder (OR = 2.18, 95% CI = 1.07–4.40), smoking (OR = 2.64, 95% CI = 1.10–6.37), anxiety symptoms (OR = 1.05, 95% CI = 1.02–1.08), and childhood maltreatment (OR = 1.04, 95% CI = 1.01–1.07) were potential associated factors of SA. In addition, anxiety symptoms had a mediating effect on the relationship between childhood maltreatment and SA.Conclusion: Adolescents and young adults with first depressive episodes and having experiences of childhood maltreatment are at a high risk of suicide. The severity of anxiety symptoms may mediate the relation between childhood maltreatment and suicide attempts in this group of patients.

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Clinical features of depressive episode with onset in adolescence and the risk of bipolar depression

Cited by 2 publications

References 19 publications

Probabilistic diagnosis of bipolar affective disorder: possibilities and limitations (literature review)

Probabilistic diagnosis of bipolar affective disorder: possibilities and limitations (literature review)

The Association Between Suicide Attempts, Anxiety, and Childhood Maltreatment Among Adolescents and Young Adults With First Depressive Episodes

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