Clinical features of endobronchial tuberculosis

Samardžić, Natalija; Jovanović, Dragana; Marković-Denić, Ljiljana; Roksandić-Milenković, Marina; Popević, Spasoje; Škodrić-Trifunović, Vesna

doi:10.2298/vsp1402156s

Cited by 8 publications

(12 citation statements)

References 21 publications

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“…In our study, bronchoscopy showed that TBTB mainly involves the upper lobes, consistent with previous reports [8,28,29]. This finding is likely because PTB commonly affects the upper lobes and obstructed drainage of secretions usually occurs in the upper lobe bronchus.…”

Section: Discussionsupporting

confidence: 92%

Incidence and Predictors of Tracheobronchial Tuberculosis in Pulmonary Tuberculosis: A Multicentre, Large-Scale and Prospective Study in Southern China

Cheng

et al. 2018

Respiration

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Background: Patients with pulmonary tuberculosis (PTB) have a high risk of concomitant tracheobronchial tuberculosis (TBTB), which commonly causes severe complications such as tracheobronchial stenosis. The prevalence and predictors of TBTB in China remain unclear due to the lack of prospective and large-scale studies. Objectives: To investigate the incidence of TBTB in PTB patients in southern China, and elucidate the predictors of TBTB and related tracheobronchial stenosis. Methods: We prospectively performed bronchoscopy in PTB patients to diagnose TBTB at four medical centres in southern China from September 2015 to August 2016. Clinical and epidemiological data were recorded and analysed to determine predictors of TBTB and related tracheobronchial stenosis. Results: A total of 345 (23.9%) of the 1,442 PTB patients undergoing bronchoscopy were diagnosed with TBTB. Female sex (OR 2.53), age < 50 years (OR 1.88), living in urban (OR 2.19), diabetes (OR 1.84), coughing (OR 2.61), and symptoms ≥4 weeks (OR 1.66) were predictors of PTB concomitant with TBTB. About 59.7% TBTB patients developed tracheobronchial stenosis, of which 23.3% cases presented severe airway narrowing. Female sex (OR 2.27), age < 50 years (OR 2.11), shortness of breath (OR 1.97), and symptoms ≥4 weeks (OR 1.71) were predictors of TBTB-related tracheobronchial stenosis. Conclusions: About 23.9% of PTB patients undergoing bronchoscopy present with TBTB in Guangdong province, southern China. Young and middle-aged females with symptoms persisting for ≥4 weeks (the main predictors of TBTB and related tracheobronchial stenosis) should receive bronchoscopy immediately when diagnosed with PTB.

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Section: Discussionsupporting

confidence: 92%

Incidence and Predictors of Tracheobronchial Tuberculosis in Pulmonary Tuberculosis: A Multicentre, Large-Scale and Prospective Study in Southern China

Cheng

et al. 2018

Respiration

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“…Cough is the most common symptom and present in 70-80% of the patient (12,21,22). Cough could be dry or with bronchorrea especially when EBTB is a part of cavitory TB (23).…”

Section: Clinical Featuresmentioning

confidence: 99%

“…Cough could be dry or with bronchorrea especially when EBTB is a part of cavitory TB (23). Fever is usually low grade but may become marked with advanced cavitory disease (12,22). Hemoptysis may occur in 15-40% of the patient but is usually mild but sometime massive hemoptysis may occur (22).…”

Section: Clinical Featuresmentioning

confidence: 99%

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Endobronchial tuberculosis—a review

Shahzad

Irfan

2016

J. Thorac. Dis.

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“…Clinical features of the EBTB are nonspecific and they differ between various types and stages of endobronchial tuberculosis [ 8 ]. Common symptoms are cough, hemoptysis, sputum production, wheezing, chest pain, fever, and dyspnea [ 8 , 9 ]. Bronchial hyperreactivity can be seen in a considerable number of patients with EBTB.…”

Section: Discussionmentioning

confidence: 99%

Endobronchial Tuberculosis Mimicking Asthma

Barış

Önyılmaz

Başyiğit

et al. 2015

Tuberculosis Research and Treatment

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Endobronchial tuberculosis (EBTB) is defined as tuberculosis infection of the tracheobronchial tree with microbial and histopathological evidence. The clinical symptoms of the diseases are nonspecific. Chronic cough is the major symptom of the disease. The diagnosis is often delayed due to its nonspecific presentation and misdiagnosed as bronchial asthma. This case is presented to recall the notion that the endobronchial tuberculosis can mimic asthma and the importance of bronchoscopic evaluation in a patient with chronic cough and treatment resistant asthma.

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Clinical features of endobronchial tuberculosis

Abstract: EBTB was more frequent among men, and among people in their fifties in our country. Detailed bronchoscopic examination, correlated with clinical and laboratory findings, will improve diagnostic rate and provide timely therapy.

Cited by 8 publications

References 21 publications

Incidence and Predictors of Tracheobronchial Tuberculosis in Pulmonary Tuberculosis: A Multicentre, Large-Scale and Prospective Study in Southern China

Incidence and Predictors of Tracheobronchial Tuberculosis in Pulmonary Tuberculosis: A Multicentre, Large-Scale and Prospective Study in Southern China

Endobronchial tuberculosis—a review

Endobronchial Tuberculosis Mimicking Asthma

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