Endobronchial Tuberculosis Mimicking Asthma

Barış, Serap Argun; Önyılmaz, Tuğba; Başyiğit, İlknur; Boyacı, Haşim

doi:10.1155/2015/781842

Cited by 9 publications

(7 citation statements)

References 8 publications

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“…For example, in countries with a high TB burden, treatments for patients with asthma should be considered carefully as there may be an increased risk of latent TB reactivation following oral corticosteroids or ICS use 111 , 112 . Furthermore, symptoms such as chronic cough may relate to asthma or TB; therefore, if the presence of TB has been excluded, asthma should be investigated 113 . In addition to geographical influencing factors, factors such as medication side effects and age can influence comorbidities and asthma control and should be considered during clinical decision-making.…”

Section: Discussionmentioning

confidence: 99%

Impact of comorbid conditions on asthmatic adults and children

Kaplan

Szefler

Halpin

2020

npj Prim. Care Respir. Med.

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Comorbid conditions (comorbidities) can complicate the diagnosis and management of asthma. In different age groups, comorbid conditions can present varying challenges, including diagnostic confusion due to mimicking asthma symptoms, exacerbation of asthma symptoms, therapy for comorbid conditions affecting asthma or therapy for asthma affecting these conditions. This review aims to summarise some common comorbid conditions with asthma, such as rhinitis, vocal cord dysfunction, gastro-oesophageal reflux, psychiatric disorders, obesity and obstructive sleep apnoea, and discuss their prevalence, symptoms, diagnosis and treatment, highlighting any differences in how they impact children and adults. Overall, there is a lack of data on the impact of treating comorbid conditions on asthma outcomes and further studies are needed to guide age-appropriate asthma management in the presence of these conditions.

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Section: Discussionmentioning

confidence: 99%

Impact of comorbid conditions on asthmatic adults and children

Kaplan

Szefler

Halpin

2020

npj Prim. Care Respir. Med.

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“… 14 In addition, endobronchial tuberculosis presenting as a polypoid, necrotic endobronchial lesion has been reported to produce symptoms mimicking asthma. 15 …”

Section: Discussionmentioning

confidence: 99%

Asthma mimic: Case report and literature review of vocal cord nodule associated with wheezing

Kashif

Singh

Aslam

et al. 2017

SAGE Open Medical Case Reports

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Asthma is a heterogeneous disease, usually characterized by chronic airway inflammation. Various clinical conditions can mimic asthma, such as foreign body aspiration, subglottic stenosis, congestive heart failure, diffuse panbronchiolitis, aortic arch anomalies, reactive airway dysfunction syndrome, chronic obstructive pulmonary disease, retrosternal goiter, vocal cord tumors, other airway tumors, and vocal cord dysfunction. Upper airway obstruction can be a life-threatening emergency. Here, we present the case of a 58-year-old female with recurrent hospital visits for wheezing and exacerbations of asthma, who was later found to have a vocal cord nodule confirmed to be squamous cell carcinoma, which was mimicking like asthma.

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“…2 TBTB is likely to be misdiagnosed as lung cancer, pneumonia and asthma due to few specific symptoms and bronchoscopic findings. 3 – 5 The delayed diagnosis of TBTB could lead to bronchial stenosis and severe complications. 6 Therefore, an early, fast diagnosis of TBTB and a reasonable anti-TB treatment are essential to reduce the incidence and spread of TB.…”

Section: Introductionmentioning

confidence: 99%

Performance of the Xpert® MTB/RIF assay in the rapid diagnosis of tracheobronchial tuberculosis using bronchial washing fluid

Song

et al. 2020

J Int Med Res

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Objective To assess the diagnostic value of the Xpert® MTB/RIF (GeneXpert) assay for tracheobronchial tuberculosis (TBTB) using bronchial washing fluid (BWF). Methods This retrospective study enrolled patients suspected of having TBTB and patients with non-TB pulmonary disease as controls. BWF were used to undertake acid-fast bacillus (AFB) smears, the GeneXpert assay and the Lӧwenstein–Jensen (LJ) culture method. The sensitivity, specificity, positive predictive value (PPV) and negative predictive value (NPV) were compared among BWF AFB smears, BWF GeneXpert and the BWF LJ culture method. Results A total of 130 patients with TBTB and 102 patients with non-TB pulmonary disease were enrolled in the study. Sputum AFB smears were positive in 62 of 130 patients (47.7%) with TBTB. Using the clinical diagnosis of TBTB as the gold standard, the sensitivity, specificity, PPV and NPV of the three methods using BWF were as follows: 93.1%, 99.0%, 99.2% and 91.8% for BWF GeneXpert; 73.1%, 100.0%, 100.0% and 74.5% for BWF LJ cultures; 53.8%, 99.0%, 98.6% and 62.7% for BWF AFB smears. The diagnostic yield of BWF GeneXpert was significantly higher compared with BWF cultures for type III and IV TBTB. Conclusion The Xpert® MTB/RIF assay using BWF exhibited higher sensitivity than bacteriological diagnostic methods and was particularly useful for the early diagnosis of smear-negative TBTB.

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Endobronchial Tuberculosis Mimicking Asthma

Cited by 9 publications

References 8 publications

Impact of comorbid conditions on asthmatic adults and children

Impact of comorbid conditions on asthmatic adults and children

Asthma mimic: Case report and literature review of vocal cord nodule associated with wheezing

Performance of the Xpert® MTB/RIF assay in the rapid diagnosis of tracheobronchial tuberculosis using bronchial washing fluid

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