Clinical features of patients with left atrial thrombus undergoing anticoagulant therapy

Abstract

D-dimer levels below 0.5 μg/mL is not enough to rule out LA thrombus in AF patients with well-controlled anticoagulation.

Blood Stasis Secondary to Heart Failure Forms Warfarin-Resistant Left Atrial Thrombus

“…Sugiura, et al reported that LAA flow velocity and d-dimer concentration predicted residual LA thrombus in patients undergoing antithrombotic therapy. 18) In their study, the predictive value of LVEF did not reach statistical significance (P = 0.087), probably because there were fewer patients (225) in their study than in our study (431). Nevertheless, Sugiura, et al suggested LVEF contributed to the formation of LA thrombus under antithrombotic therapy.…”

Risk Factors and Prognosis for Clot Formation on Cardiac Device Leads

“…6 AF is a known risk factor for atrial thrombosis, stroke, and peripheral embolism. 7,8 AF causes blood stagnancy in the RA. Most likely, cardiac device leads in the RA are a nidus on which this stagnant blood can form clot.…”

High CHA2DS2−VASc score predicts left atrial thrombus or spontaneous echo contrast detected by transesophageal echocardiography

“…CHA 2 DS 2 -VASc was an independent risk factor of LATH in some researches [5][6][7], while losing predictive value in some other studies [8][9][10]. Hence, we performed this meta-analysis aiming to determine whether CHA 2 DS 2 -VASc score has the ability to predict the presence of LA thrombus in patients with atrial fibrillation (AF).…”

“…Our search identified 6 reports [5][6][7][8][9][10] enrolling a total of 2594 patients with AF. The investigator, publication year, total number of patients, definition of left atrial thrombus, cohort study design, and risk estimate method are summarized in Table 1.…”