Clinical features of vivax malaria.

Oh, Myoung‐don; Shin, Hyung-Ik; Shin, Dong Chun; Kim, Ui Suk; Lee, Shane; Kim, Nam Joong; Choi, Mihye; Chai, Jong Yil; Choe, Kang Won

doi:10.4269/ajtmh.2001.65.143

Cited by 97 publications

(69 citation statements)

References 11 publications

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“…Similar to the current study, lymphopenia has also been reported in falciparum patients from other geographic locations (28). Depletion in the lymphocyte subsets through apoptosis (29) or due to sequestration of the cells in the lymph nodes or other body tissues (30) are some of the reasons behind the occurrence of lymphopoenia in malaria patients.…”

Section: Discussionsupporting

confidence: 72%

Parasito-haematological features of acute Plasmodium falciparum and P. vivax malaria patients with and without HIV co-infection at Wonji Sugar Estate, Ethiopia

Kassa¹,

Petros

Messele³

et al. 2005

Ethiopian Journal of Health Development

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Background: Investigation to identify factors that determine the clinical outcome of malaria are essential for the improvement of patient care in severe malaria cases. Objectives: To assess the parasitologic and haemato-immunological characteristics of malaria patients with and without HIV co-infection. Methods: Immune cells were enumerated using the Flow cytometer method. Haematological values were determined using the Coulter Counter system. Malaria parasite detection was conducted using standard microscopy; and HIV testing was conducted using Determine, ELISA and Western blot methods. Results: A total of 253 study participants, out of which 87 were control cases, and 166 were acute malaria patients (49.4% due to P. falciparum, 48.8 % due to P. vivax, 1.8% due to mixed infection) were included. Eight out of 166 (4

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Section: Discussionsupporting

confidence: 72%

Parasito-haematological features of acute Plasmodium falciparum and P. vivax malaria patients with and without HIV co-infection at Wonji Sugar Estate, Ethiopia

Kassa¹,

Petros

Messele³

et al. 2005

Ethiopian Journal of Health Development

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show abstract

“…However, even if this statement is true for these regions, atypical manifestations denoting severity have been observed in an increasing way 6,8,15 . Signs and symptoms, such as vomiting, diarrhea, jaundice, drowsiness, mental confusion, seizures, loss of consciousness, bleeding, and dyspnea, that registered in a significant percentage of patients confirm these findings.…”

Section: Rev Soc Bras Med Trop 46(1):67-72 Jan-feb 2013mentioning

confidence: 94%

Plasmodium vivax malaria: related factors to severity in the State of Maranhão, Brazil

Raposo

Santos

Santos³

et al. 2013

Rev. Soc. Bras. Med. Trop.

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Introduction: Malaria caused by Plasmodium vivax species has shown signs of severity, recorded with increasing frequency in the medical literature. This study aimed to characterize the signs of severe malaria by Plasmodium vivax in the State of Maranhão, Brazil. Methods: A descriptive cohort study of patients assisted in the field and a historical and concurrent study of a series of cases among hospitalized patients were undertaken to identify the clinical and laboratory signs of severity. Results: A total of 153 patients were included in the study, 13 of whom were hospitalized. Males made up the majority, numbering 103 (67.3%). The age of the patients ranged from 10 to 70 years, 92.2% were natives of the State of Maranhão, and 65% of the patients had had malaria before. The average time elapsed between symptom onset and diagnosis among outpatients was three days, while among hospitalized patients this average reached 15.5 days, a statistically significant difference (p=0.001). The parasitemia ranged from 500 to 10,000 parasites/µl in 92.8% of cases. The clinical and laboratory manifestations of severity were vomiting and diarrhea, jaundice, drowsiness, mental confusion, seizures, loss of consciousness, agitation, bleeding, pale skin, coughing and dyspnea, thrombocytopenia, anemia, elevation of nitrogenous compounds, and elevated transaminases and bilirubin. Conclusions: The monitoring of malaria patients with Plasmodium vivax showed the possibility of aggravation, the intensity of which varied in different circumstances, especially the interval time between falling ill and diagnostic confirmation.

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“…Geralmente a gravidade dos casos de malária está 30,31 associada à demora do diagnóstico e do tratamento , porém, como em zonas epidêmicas ou endêmicas da doença no Brasil as pessoas estão atentas aos sintomas da malária, buscando normalmente atendimento logo no início das manifestações clínicas, isso torna infrequente os quadros graves. Como cerca de 22% dos pacientes procurou atendimento com menos de 48 h; mais de 70% das pessoas incluídas nessa amostra procuraram atendimento com menos de quatro dias a partir do início dos sintomas; e a maioria dos pacientes cursava com malária pelo P. vivax, provavelmente essas são as explicações para o encontro apenas de casos não graves nessa casuística.…”

Section: Materiais E Métodosunclassified

Malária no Município de Cruzeiro do Sul, Estado do Acre, Brasil: aspectos epidemiológicos, clínicos e laboratoriais

et al. 2012

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Clinical features of vivax malaria.

Cited by 97 publications

References 11 publications

Parasito-haematological features of acute <i>Plasmodium falciparum</i> and <i>P. vivax</i> malaria patients with and without HIV co-infection at Wonji Sugar Estate, Ethiopia

Parasito-haematological features of acute <i>Plasmodium falciparum</i> and <i>P. vivax</i> malaria patients with and without HIV co-infection at Wonji Sugar Estate, Ethiopia

Plasmodium vivax malaria: related factors to severity in the State of Maranhão, Brazil

Malária no Município de Cruzeiro do Sul, Estado do Acre, Brasil: aspectos epidemiológicos, clínicos e laboratoriais

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