Clinical, Microbiological, and Biochemical Impact of the Surgical Treatment of Peri-Implantitis—A Prospective Case Series

Luengo, Fernando; Solonko, Myroslav; Sanz‐Esporrín, Javier; Sanz‐Sánchez, Ignacio; Herrera, David; Sanz, Mariano

doi:10.3390/jcm11164699

Cited by 7 publications

(9 citation statements)

References 77 publications

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“…Therefore, minimally invasive procedures have been introduced to increase patient post-surgical comfort by atraumatic acts [ 22 , 23 ]. Consequently, many new surgical and nonsurgical treatment methods for peri-implantitis management have been described; some demonstrated statistically significant clinical improvements, although the impacts on microbiological and biochemical parameters are still insufficient [ 24 , 25 , 26 , 27 ]. Therefore, primary prophylaxis of peri-implant diseases is important and can be achieved with correct treatment planning in terms of implant position, the morphologies of soft tissues surrounding the implant, and the proper prosthetic reconstruction [ 28 , 29 , 30 , 31 ].…”

Section: Discussionmentioning

confidence: 99%

An Experimental Anodized Titanium Surface for Transgingival Dental Implant Elements—Preliminary Report

Hadzik

Kubasiewicz−Ross²,

Gębarowski³

et al. 2023

JFB

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The characteristics such as microtopography, physical and chemical properties influence the behavior of an implant in a soft tissue. Anodization—as a potent method of titanium alloy surface modification—of the transgingival abutment or healing screw, has achieved some improvement. One of the possible surface treatment method is low-pressure radiofrequency oxygen plasma treatment. The aim of the study was to evaluate the chemical properties and cytocompatibility of the experimental surface. Titanium discs made of grade-23 titanium alloy (Ti-6Al-4V) anodized (A sample) with different voltage parameters (28, 67, 78, and 98 V) were included in the study. Half of the samples regarded as the “S” group were additionally treated with low-pressure radiofrequency oxygen plasma treatment. The surfaces were characterized using scanning electron microscopy, X-ray spectroscopy and Raman spectroscopy, and electrochemically investigated via a corrosion test. Furthermore, two cell lines were used, including the CHO-compatible reference line and a primary human fibroblast line for the MTT assay; direct (contact) cytotoxicity of the materials was tested with the cells, and the growth of fibroblasts on the surfaces of the different materials was tested. The morphology of the “S”-treated samples did not differ from the morphology of only-anodized samples. However, the oxygen concentration on the surface in that group slightly increased by about 1% as a result of post-trial treatment. The highest corrosion resistance was observed for both A-78 V and S-78 V samples. The cytotoxicity assay revealed no changes in cell morphology or vitality. The MTT test proved comparable culture viability among all groups; however, the “S” samples showed statistically significantly higher fibroblast proliferation and adhesion scores compared to the “A” samples. Through the in vitro study, the low-pressure radiofrequency oxygen plasma treatment of the anodized Ti-6Al-4V alloy presented itself as an auspicious option in the field of transgingival element surface modification of implants.

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Section: Discussionmentioning

confidence: 99%

An Experimental Anodized Titanium Surface for Transgingival Dental Implant Elements—Preliminary Report

Hadzik

Kubasiewicz−Ross²,

Gębarowski³

et al. 2023

JFB

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“…Patients were excluded if their periodontal condition was not adequately controlled or if the affected implant presented a vertical peri‐implant defect. Details on the study population and the peri‐implantitis surgical protocol rendered have been previously reported, as well as the 6‐month treatment outcomes (Luengo, Solonko, et al, 2022). In brief, after a pre‐surgical session of standardized oral hygiene instructions (OHI) and non‐surgical instrumentation, patients were treated with a surgical procedure based on access flap and decontamination of the implant surface combining curettes, ultrasonic tips and an air‐polishing device with glycine powder.…”

Section: Methodsmentioning

confidence: 99%

“…The sample size calculation was first calculated for the prospective case series (Luengo, Solonko, et al, 2022) based on detecting a desired inter‐group difference of 0.99 mm and a standard deviation (SD) of 0.8 mm in the primary outcome (PD) (Renvert et al, 2008). This resulted in a sample size of 25 subjects, with an α of 0.05 and a power of 99%.…”

Section: Methodsmentioning

confidence: 99%

Clinical, microbiological and biochemical impact of a supportive care protocol with an air‐polishing device, after surgical treatment of peri‐implantitis: Randomized clinical trial

Luengo

Sanz‐Esporrín

Sanz‐Sánchez

et al. 2023

Clinical Oral Implants Res

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Objectives:The aim of the present study was to evaluate the efficacy of a supportive peri-implant care (SPIC) protocol after surgical therapy of peri-implantitis, combining ultrasonic mechanical debridement and glycine powder air polishing. Materials and Methods:Thirty subjects diagnosed with peri-implantitis and treated by means of access flap were randomized 6 months later into two different SPIC groups: the test group combined a piezoelectric ultrasonic instrumentation with a specific implant PEEK tip and glycine powder air polishing, while control group received the same ultrasonic instrumentation together with a rubber cup and a polishing paste. Patients were followed for 12 months, with intermediate SPIC visits every 3 months. Clinical, radiological, microbiological and biochemical outcome variables were registered and calculated.Results: After 12 months of SPIC, probing depths (PD) showed a mean reduction of 0.33 ± 0.11 mm, with significant differences (p < .001) between the test (−0.84 ± 0.43 mm) and the control group (+0.18 ± 0.73 mm). Healthy peri-implant tissues defined by PD <5 mm, absence of BoP (or in only one site around the implant), and no additional bone loss (<0.5 mm), were observed at the final visit in 83% of the implants (87% in the test group and 80% in the control group, p = .255). No adverse events were reported by the subjects participating in the study. Conclusions:The SPIC protocol including mechanical ultrasonic debridement and glycine powder air-polishing demonstrated significantly better efficacy in terms of PD reductions. A strict SPIC protocol can maintain for 1 year, or even improve, the results obtained after surgical treatment of peri-implantitis.

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“…Open flap debridement and resective surgical peri-implantitis approaches demonstrated the improvement of the implant surface decontamination with a significant reduction in inflammatory signs such as bleeding on probing (BOP) and suppuration (SUP) along with decrease in peri-implant pocket depth (PPD) [ 11 , 12 , 13 ]. In spite of that, these methods did not achieve complete disease remission [ 14 , 15 , 16 , 17 ], resulting in different levels of treatment failure or implant loss (20–60%) in the short-term basis. As a result, the treated implant sites remain meagre in the original supporting bone structure causing the reduction of previously achieved implant stability.…”

Section: Introductionmentioning

confidence: 99%

Reconstructive Peri-Implantitis Therapy by Using Bovine Bone Substitute with or without Hyaluronic Acid: A Randomized Clinical Controlled Pilot Study

Rakašević

Šćepanović

Mijailović

et al. 2023

JFB

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Background: The present pilot study aimed to assess clinical and radiographic efficiencies of bovine bone substitute (BBS) merged with hyaluronic acid (HA) in peri-implantits reconstructive surgery. Methods: Peri-implantitis (diagnosed 6.03 ± 1.61 years of implant loading) bone defects were randomly treated either with BBS plus HA (test group) or BBS alone (control group). Clinical parameters including peri-implant probing depth (PPD), bleeding on probing (BOP), implant stability (ISQ), and radiographic changes in vertical and horizontal marginal bone (MB) levels were assessed at six months postoperatively. New temporary and permanent screw-retained crowns were made at two weeks and three months postoperatively. Data were analyzed using parametric and non-parametric tests. Results: In both groups, 75% of patients and 83% of implants achieved treatment success after six months (no BOP, PPD <5 mm, and no further MB loss). Clinical outcomes improved over time within groups; however, without significant difference between them. ISQ value obtained significant increases in the test compared to the control group at six months postoperatively (p < 0.05). The vertical MB gain was significantly greater in the test group compared to the control (p < 0.05). Conclusions: Short-term outcomes suggested that BBS merged with HA could improve clinical and radiographic outcomes in peri-implantitis reconstructive therapy.

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Clinical, Microbiological, and Biochemical Impact of the Surgical Treatment of Peri-Implantitis—A Prospective Case Series

Cited by 7 publications

References 77 publications

An Experimental Anodized Titanium Surface for Transgingival Dental Implant Elements—Preliminary Report

An Experimental Anodized Titanium Surface for Transgingival Dental Implant Elements—Preliminary Report

Clinical, microbiological and biochemical impact of a supportive care protocol with an air‐polishing device, after surgical treatment of peri‐implantitis: Randomized clinical trial

Reconstructive Peri-Implantitis Therapy by Using Bovine Bone Substitute with or without Hyaluronic Acid: A Randomized Clinical Controlled Pilot Study

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