Clinical ocular findings in a colony of chinchillas (<i>Chinchilla laniger</i>)

Peiffer, Robert L.; Johnson, Philip T.

doi:10.1258/002367780781071094

Cited by 29 publications

(33 citation statements)

References 6 publications

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“…The average IOP value was smaller than that which was previously estimated by applanation tonometer in chinchillas (PEIFFER & JOHNSON, 1980;LIMA et al, 2010). Because differences have been observed between applanation tonometry and rebound tonometry, the results of one method cannot be applied to another.…”

Section: Discussionmentioning

confidence: 56%

“…Chinchillas are bred for the fur trade, employed as a model in ophthalmic research and produced increasingly as pets (PEIFFER & JOHNSON, 1980;WILLIAMS, 2007;MÜLLER et al, 2010, MÜLLER & EULE, 2014. Moreover, studies describing ophthalmic parameters in chinchillas are scarce (PEIFFER & JOHNSON, 1980;LIMA et al, 2010;MÜLLER et al, 2010;BERCHT et al, 2015).…”

Section: Clinic and Surgerymentioning

confidence: 99%

“…Moreover, studies describing ophthalmic parameters in chinchillas are scarce (PEIFFER & JOHNSON, 1980;LIMA et al, 2010;MÜLLER et al, 2010;BERCHT et al, 2015). Other features that make this animal desirable for model research include its small size and ease handling (PEIFFER & JOHNSON, 1980;MÜLLER et al, 2010). The aim of this research was to measure the IOP of normal chinchilla eyes using the rebound tonometer.…”

Section: Clinic and Surgerymentioning

confidence: 99%

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Assessment of intraocular pressure in chinchillas of different age groups using rebound tonometry

2016

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The aim of this research was to measure the intraocular pressure (IOP) of normal chinchilla eyes using the rebound tonometer. A further aim was to assess whether there were differences in the values of intraocular pressure in relation to animals age, gender and time of day. Thirty-six chinchillaswere divided into three groups of 12 chinchillas each, by age: , Group II (20 and 34 months) and Group III (37 and 135 months RESUMO Objetivou-se aferir a pressão intraocular (PIO) em olhos saudáveis de chinchilas usando o tonômetro de rebote. Além disso, pretende-se verificar se existem diferenças nos valores de pressão intraocular em relação à idade e ao sexo dos animais e o período do dia. Trinta e seis chinchilas foram divididas em três grupos com 12 animais cada, considerando as idades, designados por GI (2-6 meses), GII (20-34 meses) e GIII (37-135 meses

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Section: Discussionmentioning

confidence: 56%

Section: Clinic and Surgerymentioning

confidence: 99%

Section: Clinic and Surgerymentioning

confidence: 99%

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Assessment of intraocular pressure in chinchillas of different age groups using rebound tonometry

2016

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“…Food and hair impaction into periodontal pockets can also lead to lateral and tooth root abscessation (Hoefer and Crossley, 2002). Peiffer and Johnson (1980) examined the eyes of 14 chinchillas, ages 6-17 years old. 9.10) or CT of the skull to best assess the extent of tooth root abnormalities is strongly recommended (Donnelly, 2004).…”

Section: Malocclusionmentioning

confidence: 99%

Biology and Diseases of Chinchillas

Hsu

Chan²,

Wheler

2015

Laboratory Animal Medicine

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“…In addition to humans, AH has been observed in dogs, 31,32 chinchillas, 33 cats, 32 and rabbits. 34 While none of these specific animals consistently develop bilateral AH, we have observed that young (9-month old or less) male beagles fed a diet containing 30% galactose for 42 months all developed AH.…”

Section: The Galactose-fed Dogmentioning

confidence: 99%

Asteroid hyalosis: pathogenesis and prospects for prevention

Kador

Wyman

2008

Eye

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Asteroid hyalosis (AH) is a common degenerative process in which fatty calcium globules collect within the vitreous humour. The condition rarely causes visual disturbances, and surgical removal is only rarely required. The presence of AH has been associated with systemic diseases such as diabetes; however, research in this area has been hampered by the lack of an animal model of AH. Recently, we have reported that AH occurs in galactose-fed beagles that develop the advanced stages of diabetes-like retinopathy. Comparisons of vitreous humour containing asteroid bodies (ABs) collected from these galactose-fed beagles and vitreous samples from age-matched normal beagles without ABs indicate that ABs contain calcium and phosphorous. Subtraction analysis of chloroform extracts of the vitreous samples by electrospray mass spectroscopy resulted in the identification of the quasimolecular ion of 1,2-dipalmitoyl-glycero-3-phosphoethanolamine (DPPE) as the main component of ABs. Since several reports indicate that ABs are composed of lipid-calcium complexes, we have proposed that the main component of ABs in the galactose-fed dogs with AH is a quasimolecular ion of DPPE in which two molecules of DPPE are complexed through their phosphates groups with calcium. We suggest that these lipid components diffuse into the vitreous from the degenerating retinas of these dogs.

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Clinical ocular findings in a colony of chinchillas (Chinchilla laniger)

Cited by 29 publications

References 6 publications

Assessment of intraocular pressure in chinchillas of different age groups using rebound tonometry

Assessment of intraocular pressure in chinchillas of different age groups using rebound tonometry

Biology and Diseases of Chinchillas

Asteroid hyalosis: pathogenesis and prospects for prevention

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