Clinical outcome of Descemet's stripping endothelial keratoplasty with femtosecond laser‐prepared grafts

Ivarsen, Anders; Hjortdal, Jesper

doi:10.1111/aos.13672

Cited by 2 publications

(5 citation statements)

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“…[ 11 12 ] However, the comparability of FSL and MK-assisted donor lenticules in terms of surface smoothness, endothelial cell viability, and clinical outcomes is a matter of debate. [ 6 7 8 9 11 12 ]…”

Section: Discussionmentioning

confidence: 99%

“…who reported poor graft adhesion with suboptimal visual acuity and quality with FSL-assisted donor lenticules. [ 8 ]…”

Section: Discussionmentioning

confidence: 99%

“…[ 17 ] However, increased endothelial cell loss has been reported with this method with poor graft adhesion and a significantly higher re-bubbling rate. [ 8 18 ]…”

Section: Discussionmentioning

confidence: 99%

“…[ 6 7 ] On the contrary, a more irregular interface with poor graft adhesion has also been reported with the use of FSL-donor lenticules. [ 8 9 ] The ultrastructural changes in corneal endothelium after FSL application have not been well-characterized.…”

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confidence: 99%

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Surface quality and endothelial cell viability after femtosecond laser-assisted donor lenticule preparation for endothelial keratoplasty - An in-vitro study

Titiyal

Aravind

Kaur

et al. 2020

Indian J Ophthalmol

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Section: Discussionmentioning

confidence: 99%

“…who reported poor graft adhesion with suboptimal visual acuity and quality with FSL-assisted donor lenticules. [ 8 ]…”

Section: Discussionmentioning

confidence: 99%

“…[ 17 ] However, increased endothelial cell loss has been reported with this method with poor graft adhesion and a significantly higher re-bubbling rate. [ 8 18 ]…”

Section: Discussionmentioning

confidence: 99%

mentioning

confidence: 99%

See 2 more Smart Citations

Surface quality and endothelial cell viability after femtosecond laser-assisted donor lenticule preparation for endothelial keratoplasty - An in-vitro study

Titiyal

Aravind

Kaur

et al. 2020

Indian J Ophthalmol

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“…Бóльшая часть имеющихся публикаций на эту тему посвящена результатам задней послойной кератопластики с применением низкоэнергетических фемтолазерных систем [12][13][14]. Результаты при этом не всегда бывают сопоставимы с таковыми при ЗАПК [15,16].…”

Section: Introductionunclassified

Inverted Posterior Femto-Keratoplasty: Quality of the Surface of the Corneal Section and Preliminary Clinical Outcomes

et al. 2020

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Purpose. To evaluate the quality of the surface of an ultra-thin donor transplant prepared from the endothelial surface of the cornea using a femtosecond laser and to demonstrate the preliminary clinical results. Patients and Methods. 4 eyes were operated: 3 with Fuch`s endothelial dystrophy and 1 with pseudophakic bullous keratopathy. All patients were treated with DSEK with an ultrathin graft prepared by Alcon Wavelight FS 200 femtosecond laser (Germany). Before and after surgery UCVA, BSCVA, astigmatism, ECD were measured. EC death, graft thickness and CCT were evaluated at 12 months` observation. Atomic force microscopy was used for examination of 10 samples. Control group was 5 corneal flaps obtained by mechanical microkeratome (Moria SLK-2, France). Main group — 5 corneal flaps, obtained by femtosecond laser. Nonparametric Mann-Whitney test was used for statistical analysis. Coefficient of reliability p < 0.05 was considered to be significant. Results. RMS value of femto-laser group samples was 18.6 ± 7.8 um. RMS of microkeratome group samples was 22.3 ± 18.3 um. Statistical analysis did not reveal significant differences between the values of the studied parameter in these groups (p > 0.05). Transparent engraftment was observed in all cases, no corneal edema was identified. BSCVA ranged from 0.2 to 0.6, which was associated with the presence of concomitant pathology. Astigmatism was 1.35 ± 1.0 D. ECD = 1526 ± 434 cells/mm2. EC loss = 48.0 ± 12.8 %. Graft thickness in the central zone was 78.0 ± 18.1 µm. Center-Edge Index — 0.84 ± 0.12. CCT = 600 ± 31 um. No postoperative complications were found. Conclusion. The developed settings allowed to obtain high-quality ultra-thin graft with a sufficiently uniform surface without a risk of perforation. Preliminary clinical results showed the method potential for restoration of corneal transparency. ECD loss corresponded to the one achievable by DSAEK.

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Clinical outcome of Descemet's stripping endothelial keratoplasty with femtosecond laser‐prepared grafts

Cited by 2 publications

References 4 publications

Surface quality and endothelial cell viability after femtosecond laser-assisted donor lenticule preparation for endothelial keratoplasty - An in-vitro study

Surface quality and endothelial cell viability after femtosecond laser-assisted donor lenticule preparation for endothelial keratoplasty - An in-vitro study

Inverted Posterior Femto-Keratoplasty: Quality of the Surface of the Corneal Section and Preliminary Clinical Outcomes

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