Clinical outcomes of canaloplasty via an ab-interno surgical technique using the iTrack device: a narrative review

Koerber, Norbert; Ondrejka, Simon

doi:10.1007/s10792-022-02601-1

Cited by 5 publications

(2 citation statements)

References 35 publications

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“…In our study, we have performed ab-interno canaloplasty, which is a nonimplant MIGS that targets all resistance sites of the conventional outflow pathway, offering a comprehensive approach to IOP reduction, with no disruption to the trabecular meshwork 15,16 . Its effectiveness in reducing IOP and medication burden is proven in the literature 17 as well as in our previous study that presented the 4-year outcomes, highlighting that IOP and medication reduction were sustained up to 48 months postoperatively 7 . In this study, the same cohort confirms that these benefits provided by canaloplasty are still sustained 6 years after the procedure, with a mean reduction in IOP and number of medications of 27% and 52%, respectively, at the last follow-up.…”

Section: Discussionmentioning

confidence: 99%

6-Year Efficacy and Safety of iTrack Ab-Interno Canaloplasty as a Stand-Alone Procedure and Combined With Cataract Surgery in Primary Open Angle and Pseudoexfoliative Glaucoma

Koerber,

Ondrejka

2023

Journal of Glaucoma

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Précis: Significant reductions in IOP and number of medications are sustained up to 6 years postoperatively for eyes that underwent ab-interno canaloplasty using the iTrack microcatheter, either as a standalone procedure or combined with cataract surgery. Purpose: To evaluate the long-term effectiveness of iTrack (Nova Eye Medical, Inc.) ab-interno canaloplasty for reducing intraocular pressure (IOP) and number of glaucoma medications in patients with primary open-angle (POAG) and pseudoexfoliative (PEX) glaucoma. Methods: A retrospective single-center consecutive case series. Patients were treated with either ab-interno canaloplasty performed as a standalone procedure, or combined with cataract surgery, and were followed for up to 6 years. iTrack was used to circumferentially catheterize and viscodilate Schlemm’s canal over 360°. Primary efficacy endpoints included intraocular pressure (IOP) and number of glaucoma medications at 12, 24, 36, 48, 60, and 72 months after surgery. Results: 27 eyes of 22 patients, with a mean age of 76.9±6.3 years, were recruited. Mean IOP was reduced significantly from 19.9±5.2 mmHg (n=27) at baseline (no washout) to 14.6±3.3 mmHg at the 6-year follow-up (n=18; P<0.001). The number of medications was significantly reduced from 1.9±1 at baseline to 0.9±0.9 at 6 years (n=18; P=0.005). At all timepoints there was no statistical difference between POAG (n=16) and PEX (n=11) eyes, nor between standalone procedures (n=4) and those combined with phacoemulsification (n=23). At 72 months, the mean reduction in IOP was 27% while 53% in the number of medications. No serious complications were recorded. Conclusion: iTrack ab-interno canaloplasty performed as a standalone procedure, or in combination with cataract surgery, significantly reduced IOP and number of medications in patients with POAG up to 6 years after the procedure. To the authors’ knowledge, this is the longest ab-interno canaloplasty follow-up available in the literature.

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Section: Discussionmentioning

confidence: 99%

6-Year Efficacy and Safety of iTrack Ab-Interno Canaloplasty as a Stand-Alone Procedure and Combined With Cataract Surgery in Primary Open Angle and Pseudoexfoliative Glaucoma

Koerber,

Ondrejka

2023

Journal of Glaucoma

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“…Pressure parameters provide an important basis for understanding the changes in the internal environment and the damage to surrounding tissues. Pressure microcatheters can also be used for pressure testing of intracardiac pressure, pulmonary artery pressure, intrarenal pressure, and other organs. − For intracardiac pressure, thermal dilution or piezoelectric sensing principles are usually used for detection. The thermodilution technique is a method of determining the magnitude of intracardiac pressure by detecting temperature changes within the heart or blood vessels due to an indicator fluid by a catheter or guidewire .…”

Section: Clinical Catheter-based Surgical Instrumentsmentioning

confidence: 99%

Advances in Multifunctional Electronic Catheters for Precise and Intelligent Diagnosis and Therapy in Minimally Invasive Surgery

Huang,

Liu

et al. 2024

ACS Nano

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The advent of catheter-based minimally invasive surgical instruments has provided an effective means of diagnosing and treating human disease. However, conventional medical catheter devices are limited in functionalities, hindering their ability to gather tissue information or perform precise treatment during surgery. Recently, electronic catheters have integrated various sensing and therapeutic technologies through micro/ nanoelectronics, expanding their capabilities. As micro/nanoelectronic devices become more miniaturized, flexible, and stable, electronic surgical catheters are evolving from simple tools to multiplexed sensing and theranostics for surgical applications. The review on multifunctional electronic surgical catheters is lacking and thus is not conducive to the reader's comprehensive understanding of the development trend in this field. This review covers the advances in multifunctional electronic catheters for precise and intelligent diagnosis and therapy in minimally invasive surgery. It starts with the summary of clinical minimally invasive surgical instruments, followed by the background of current clinical catheter devices for sensing and therapeutic applications. Next, intelligent electronic catheters with integrated electronic components are reviewed in terms of electronic catheters for diagnosis, therapy, and multifunctional applications. It highlights the present status and development potential of catheter-based minimally invasive surgical devices, while also illustrating several significant challenges that remain to be overcome.

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Minimal-Invasive Glaukom-Eingriffe (MIGS)

Knorr,

Lelgemann

2024

Springer Reference Medizin

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Clinical outcomes of canaloplasty via an ab-interno surgical technique using the iTrack device: a narrative review

Cited by 5 publications

References 35 publications

6-Year Efficacy and Safety of iTrack Ab-Interno Canaloplasty as a Stand-Alone Procedure and Combined With Cataract Surgery in Primary Open Angle and Pseudoexfoliative Glaucoma

6-Year Efficacy and Safety of iTrack Ab-Interno Canaloplasty as a Stand-Alone Procedure and Combined With Cataract Surgery in Primary Open Angle and Pseudoexfoliative Glaucoma

Advances in Multifunctional Electronic Catheters for Precise and Intelligent Diagnosis and Therapy in Minimally Invasive Surgery

Minimal-Invasive Glaukom-Eingriffe (MIGS)

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