Clinical outcomes of keratitis

Green, Matthew; Apel, Andrew; Naduvilath, Thomas; Stapleton, Fiona

doi:10.1111/j.1442-9071.2007.01511.x

Cited by 74 publications

(67 citation statements)

References 20 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…This rate of culture positivity is comparable to the 40% to 73% culture positivity rates reported in earlier studies from Australia [19], France [18], and other parts of the world [20–23]. …”

Section: Discussionsupporting

confidence: 87%

Spectrum of Bacterial Keratitis at a Tertiary Eye Care Centre in India

Kaliamurthy

Kalavathy

Parmar

et al. 2013

BioMed Research International

View full text Add to dashboard Cite

Aim. To report the aetiological spectrum and susceptibility patterns of bacteria isolated from patients with corneal ulceration. Method. The microbiological data of all patients with suspected infectious corneal ulceration who presented to the ocular microbiology service at this centre between 2005 and 2012 were reviewed retrospectively. Result. Microorganisms were recovered from 1665 (77%) of the 2170 ulcers. Bacterial isolates accounted for 1205 of the organisms isolated. The most common bacterial pathogens isolated were various species of Staphylococcus, representing 777 (64.5%), followed by Staphylococcus spp. (148; 12.3%) and Pseudomonas aeruginosa (117; 9.7%). High percentages of Gram-positive bacteria were susceptible to gatifloxacin (>94%), followed by ofloxacin and moxifloxacin. Almost 90% of Pseudomonas aeruginosa isolates were susceptible to ciprofloxacin and moxifloxacin. Sixty-two (44%) of 140 isolates of Streptococcus pneumoniae, 79 (14.8%) of 534 isolates of Staphylococcus epidermidis, and 33 (14%) of 234 isolates of Staphylococcus aureus were resistant to three or more antibiotics. Conclusion. Staphylococcus spp. were the most common bacterial pathogens isolated from patients with keratitis in this setting. High percentages of Gram-positive and Gram-negative bacteria were susceptible to gatifloxacin and moxifloxacin, respectively. Interestingly, a high percentage of Streptococcus pneumoniae isolates were found to be resistant to three or more antibiotics.

show abstract

Section: Discussionsupporting

confidence: 87%

Spectrum of Bacterial Keratitis at a Tertiary Eye Care Centre in India

Kaliamurthy

Kalavathy

Parmar

et al. 2013

BioMed Research International

View full text Add to dashboard Cite

show abstract

“…Delay of even a few hours, especially in cases of microbial keratitis caused by Pseudomonas, may have an adverse impact on treatment outcome [20]. In their study, Green et al found that poor visual outcomes in cases with microbial keratitis were associated with severe disease at presentation that may be related to delay in treatment of cases [1]. The median duration of symptoms before initial examination in the study by Laibson et al was 11.4 days [2].…”

Section: Discussionmentioning

confidence: 98%

“…Microbial keratitis is a serious ocular infectious disease that can lead to significant loss of vision, or even loss of eye in some cases [1][2][3][4]. The severity and outcome of the infection typically depends on the virulence of the organism, and the visual prognosis relies on prompt intensive antimicrobial treatment in response to microbiological investigations [5,6].…”

Section: Introductionmentioning

confidence: 99%

Clinical review of corneal ulcers resulting in evisceration and enucleation in elderly population

Constantinou

Jhanji

Tao

et al. 2009

Graefes Arch Clin Exp Ophthalmol

View full text Add to dashboard Cite

show abstract

“…Prior reports on microbial keratitis (bacterial, fungal, and viral) have demonstrated that older patients may have worse prognoses and outcomes compared with younger patients. [14][15][16] This association may be the result of reduced immunity in the elderly or different risk factors affecting the population. 14 Two separate studies in South India have found the microbial keratitis to affect men more than women.…”

Section: Discussionmentioning

confidence: 99%

Predictors of outcome in fungal keratitis

Prajna

Krishnan

Mascarenhas

et al. 2012

Eye

View full text Add to dashboard Cite

Purpose To analyse predictors of clinical outcome in fungal keratitis. Methods Data was collected during a prospective, randomized, controlled, doublemasked clinical trial of treatment for fungal keratitis. Clinical features at presentation and demographics were collected at the enrolment visit for all patients. Pre-specified clinical outcomes included 3-month visual acuity and infiltrate/scar size, time to re-epithelialization, and corneal perforation. A separate multivariable model with each outcome as the dependent variable included all predictor variables.

show abstract

Clinical outcomes of keratitis

Abstract: An outcome of poor vision, vision loss during treatment, surgical intervention or complication of keratitis is more likely in patients with severe keratitis, keratitis related to prior ocular surface disease or older age.

Cited by 74 publications

References 20 publications

Spectrum of Bacterial Keratitis at a Tertiary Eye Care Centre in India

Spectrum of Bacterial Keratitis at a Tertiary Eye Care Centre in India

Clinical review of corneal ulcers resulting in evisceration and enucleation in elderly population

Predictors of outcome in fungal keratitis

Contact Info

Product

Resources

About