2021
DOI: 10.1016/j.clml.2021.06.022
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Clinical Outcomes of Patients With Newly Diagnosed Acute Lymphoblastic Leukemia in a County Hospital System

Abstract: This is a PDF file of an article that has undergone enhancements after acceptance, such as the addition of a cover page and metadata, and formatting for readability, but it is not yet the definitive version of record. This version will undergo additional copyediting, typesetting and review before it is published in its final form, but we are providing this version to give early visibility of the article. Please note that, during the production process, errors may be discovered which could affect the content, a… Show more

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Cited by 3 publications
(1 citation statement)
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“…A limitation of Blinotumamab 7 and other non-IgG-like bispecifics 8,9 is that these molecules lack fragment crystallizable domains and have short halflives, which necessitate continuous high dose intravenous infusions. Moreover, this intensive regimen can be challenging for patients, especially those with limited hospital access 10,11 . A range of methods have been utilized in an attempt to extend biologic half-life of non-IgG-like bispecifics 12 , including conjugation with small molecules, fragment crystallizable domains, or albumin binding motifs.…”
Section: Introductionmentioning
confidence: 99%
“…A limitation of Blinotumamab 7 and other non-IgG-like bispecifics 8,9 is that these molecules lack fragment crystallizable domains and have short halflives, which necessitate continuous high dose intravenous infusions. Moreover, this intensive regimen can be challenging for patients, especially those with limited hospital access 10,11 . A range of methods have been utilized in an attempt to extend biologic half-life of non-IgG-like bispecifics 12 , including conjugation with small molecules, fragment crystallizable domains, or albumin binding motifs.…”
Section: Introductionmentioning
confidence: 99%