2003
DOI: 10.1046/j.0306-5251.2003.01877.x
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Clinical pharmacology of old age syndromes

Abstract: Several syndromes occur in old age. They are often associated with increased mortality and in all there is a paucity of basic and clinical research. The recent developments in the clinical pharmacology of three common syndromes of old age (delirium, urinary incontinence, and falls) are discussed along with directions for future research.

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Cited by 5 publications
(2 citation statements)
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References 164 publications
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“…Shorteracting preparations are preferable [57]. Chlormethiazole is not recommended for older patients because of its effect on respiration, car-diovascular complications and the unpredictability of the serum levels achieved [18].…”
Section: Pharmacological Approachesmentioning
confidence: 99%
“…Shorteracting preparations are preferable [57]. Chlormethiazole is not recommended for older patients because of its effect on respiration, car-diovascular complications and the unpredictability of the serum levels achieved [18].…”
Section: Pharmacological Approachesmentioning
confidence: 99%
“…Long-term use can lead to tolerance, habituation, dependence and withdrawal syndromes. 21,45,58 Withdrawal can give rise to a syndrome that manifests as tremors, diaphoresis, photophobia, insomnia, abdominal discomfort, hypertension, and seizures. 59 Despite concerns about efficacy and substantial evidence of problematic side-effects, antipsychotics and anxiolytics are commonly administered for the calming of agitated older patients, especially when nursing shortages are acute and/or expert review is unavailable.…”
Section: Chemical Restraintmentioning
confidence: 99%