Clinical practice guidelines in intracerebral haemorrhage

Rodríguez‐Yáñez, Manuel; Castellanos, Mar; Freijó, Marimar; Fernández, J.C. López; Martí‐Fàbregas, Joan; Nombela, Florentino; Simal, Patricia; Castillo, J.; Díez‐Tejedor, Exuperio; Fuentes, Blanca; Leciñana, M. Alonso de; Álvarez-Sabín, José; Arenillas, Juan F.; Calleja, Sergio; Casado, I.; Dávalos, Antonio; Fernando, Daniel; Egido, J.A.; Gállego, J.; Pastor, A. García; Gil‐Núñez, A.; Gilo, F.; Irimia, P.; Lago, Aída; Maestre, J.; Masjuán, Jaime; Martínez‐Sánchez, P.; Martínez‐Vila, E.; Molina, Carlos A.; Morales, A.; Purroy, Francisco; Ribó, Marc; Roquer, Jaume; Rubio, Francisco; Segura, Tomás; Serena, Joaquı́n; Tejada, J.; Vivancos, José

doi:10.1016/j.nrleng.2011.03.011

Cited by 26 publications

(18 citation statements)

References 101 publications

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“…In the trend, there was a decrease in GCS followed by an increase in mortality. This is in line with a previous study of GCS by Castellanos et al 2005 and Davis et al 2006 12,13 . The results of our study that showed an increase in volume increasing the mortality rate of ICH patients with significant results (P = 0.024).…”

Section: Discussionsupporting

confidence: 93%

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Profile of Clinical and Radiological Factors of Intracerebral Hemorrhage Stroke Patients in Dr. Soetomo Hospital

Muharram

Fauzi

Rahardjo

et al. 2019

Universitas Airlangga

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Introduction: ICH (intracerebral hemorrhage) is a medical emergency with high mortality and morbidity that occurs in 15-20% of stroke cases. However, in the Multicenter Surgical Trial in Lobar ICH (STICH) study no benefit was found from the initial operative handler in Lobar ICH patients. Many clinical and radiological factors that affect outcomes of patients.Methods: The design of this study was a cross-sectional study. Clinical and radiological factors were analyzed by chi-square test and Kruskal-Wallis test. Then significant results were sought Relative RiskResults: This research was conducted from January 2017 to September 2018 starting from sampling to processing data. Sampling was carried out at the medical record center of Dr. Hospital. Soetomo Surabaya. Data collection is done by using secondary data in the form of patient medical records. All of the collected intracerebral hemorrhage patients were 302 and the total patients who met the inclusion and exclusion criteria were included in the study as the study subjects. Patients who met the criteria obtained 247 research subjects.Conclusion: There are several factors that influence the outcome of ICH stroke patients. Radiological factors and clinical factors both have an impact on outcomes. Further research is needed to find out which factors can be a diagnosis for choosing treatments that provide better outcomes. Statistically more than 1 variable is needed to determine an action that results in a more significant outcome of living patients. This shows that the choice of treatment for patients with different characteristics requires different treatments. Further analysis is needed to look for indications of the use of Operative or Conservative actions16.

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Section: Discussionsupporting

confidence: 93%

“…GCS variables were divided into three categories, namely the conscious category (> 13), unconscious (5)(6)(7)(8)(9)(10)(11)(12)(13) and unconscious (<5). It can be seen that the percentage of GCS respondents in the conscious category (0-4) is 28.3% with a frequency of 70 respondents.…”

Section: Glasgow Coma Scale (Gcs)mentioning

confidence: 99%

Profile of Clinical and Radiological Factors of Intracerebral Hemorrhage Stroke Patients in Dr. Soetomo Hospital

Muharram

Fauzi

Rahardjo

et al. 2019

Universitas Airlangga

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“…All patients were admitted to an acute stroke unit and treated according to the guidelines of the Cerebrovascular Diseases Study Group of the Spanish Society of Neurology . Clinical variables are detailed in Appendix S1.…”

Section: Methodssupporting

confidence: 88%

Inflammation, edema and poor outcome are associated with hyperthermia in hypertensive intracerebral hemorrhages

Iglesias‐Rey

Rodríguez‐Yáñez

Arias

et al. 2018

Euro J of Neurology

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Background and purposeThe deleterious effect of hyperthermia on intracerebral hemorrhage (ICH) has been studied. However, the results are not conclusive and new studies are needed to elucidate clinical factors that influence the poor outcome. The aim of this study was to identify the clinical factors (including ICH etiology) that influence the poor outcome associated with hyperthermia and ICH. We also tried to identify potential mechanisms involved in hyperthermia during ICH.MethodsWe conducted a retrospective study enrolling patients with non‐traumatic ICH from a prospective registry. We used logistic regression models to analyze the influence of hyperthermia in relation to different inflammatory and endothelial dysfunction markers, hematoma growth and edema volume in hypertensive and non‐hypertensive patients with ICH.ResultsWe included 887 patients with ICH (433 hypertensive, 50 amyloid, 117 by anticoagulants and 287 with other causes). Patients with hypertensive ICH showed the highest body temperature (37.5 ± 0.8°C) as well as the maximum increase in temperature (0.9 ± 0.1°C) within the first 24 h. Patients with ICH of hypertensive etiologic origin, who presented hyperthermia, showed a 5.3‐fold higher risk of a poor outcome at 3 months. We found a positive relationship (r = 0.717, P < 0.0001) between edema volume and hyperthermia during the first 24 h but only in patients with ICH of hypertensive etiologic origin. This relationship seems to be mediated by inflammatory markers.ConclusionOur data suggest that hyperthermia, together with inflammation and edema, is associated with poor outcome only in ICH of hypertensive etiology.

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“…Patients were treated in the emergency service of a single tertiary university hospital (University Clinical Hospital of Santiago de Compostela [Spain]) by trained health personnel and later admitted to the stroke unit and treated by neurologists specialized in cerebrovascular treatment according to a protocol based on Spanish and international clinical guidelines. 18,19 Standard protocol approvals, registrations, and patient consents This study was carried out in accordance with the Helsinki Declaration of the World Medical Association (2008) and approved by the Clinical Research Ethics Committee of Galicia. Informed consent was obtained from patients or their relatives at the time of inclusion in the registry, authorizing the anonymous use of data for further studies.…”

Section: Methodsmentioning

confidence: 99%

Antihyperthermic treatment decreases perihematomal hypodensity

et al. 2020

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ObjectiveTo investigate the effect on perihematomal hypodensity and outcome of a decrease in body temperature in the first 24 hours in patients with intracerebral hemorrhage (ICH). MethodsIn this retrospective study on a prospectively registered database, among the 1,100 patients, 795 met all the inclusion criteria. Temperature variations in the first 24 hours and perihematomal hypodensity (PHHD) were recorded. Patients ≥37.5°C were treated with antihyperthermic drugs for at least 48 hours. The main objective was to determine the association among temperature variation, PHHD, and outcome at 3 months. ResultsThe decrease in temperature in the first 24 hours increased the possibility of good outcome 11-fold. Temperature decrease, lower PHHD volume, and a good outcome were observed in 31.8% of the patients who received antihyperthermic treatment. ConclusionThe administration of early antihyperthermic treatment in patients with spontaneous ICH with a basal axillary temperature ≥37.5°C resulted in good outcome in a third of the treated patients.Glossary ANOVA = analysis of variance; CI = confidence interval; ICH = intracerebral hemorrhage; mRS = modified Rankin Scale; NIHSS = NIH Stroke Scale; OR = odds ratio; PHHD = perihematomal hypodensity.

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Clinical practice guidelines in intracerebral haemorrhage

Cited by 26 publications

References 101 publications

Profile of Clinical and Radiological Factors of Intracerebral Hemorrhage Stroke Patients in Dr. Soetomo Hospital

Profile of Clinical and Radiological Factors of Intracerebral Hemorrhage Stroke Patients in Dr. Soetomo Hospital

Inflammation, edema and poor outcome are associated with hyperthermia in hypertensive intracerebral hemorrhages

Antihyperthermic treatment decreases perihematomal hypodensity

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