Background: herniated disc usually presents pain accompanied with paresthesia and loss of muscle strength, causing limitations in the activities of daily life. Among the therapeutic strategies aimed at obtaining an improvement in the symptomatology, highlights the Osteopathic manipulation.Methods: 11 computerized databases were consulted. Regarding the eligibility criteria, only articles of the randomized controlled clinical trial type were included. The tool for assessing the risk of bias was the one proposed by Cochrane.Results: A total of 3 randomized controlled clinical trials were selected and considered low risk of bias. The results showed an improvement in all the variables measured in the experimental group of osteopathic manipulation. However, the improvement was greater in the study group that was underwent surgery.Conclusions: lumbar manipulation spinal is an effective technique to improve the symptomatology of pain originating from a herniated lumbar disc. None of the participants had adverse reactions and their outcome improved significantly in the short and long term. Nevertheless, the studies obtained were limited in number.