Clinical Profile of Acute Poisoning in Children at a Teaching Hospital in Lalitpur

Dhakal, Ajaya Kumar; Shrestha, Devendra; Shakya, Archana; Shah, Sc C.; Shakya, Henish

doi:10.3126/jnps.v34i2.10139

Cited by 10 publications

(11 citation statements)

References 6 publications

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“…Few studies on epidemiology and clinical profile of poisoning have been conducted in Nepal, but most of them are confined to the central and western region and mainly observed on retrospective hospital-based data. [ 8 9 ] However, little is known about the pattern of poisoning in the eastern part of Nepal. Furthermore, there is a paucity of studies on the clinical profile and mortality parameters for poisoning patients in ICU in Nepal.…”

Section: Introductionmentioning

confidence: 99%

Clinical profile and outcome of patients with acute poisoning admitted in intensive care unit of tertiary care center in Eastern Nepal

Rajbanshi¹,

Arjyal²,

Mandal³

2018

Indian Journal of Critical Care Medicine

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Background:Acute poisoning is a common health-care problem requiring admission in the intensive care unit (ICU) in the developing countries. The study was conducted to assess the epidemiological parameters of acute poisoning and factors affecting clinical course and outcome of the patients in ICU in the eastern part of Nepal.Methodology:This was a prospective observational study conducted at ICU of tertiary care hospital in the eastern part of Nepal for the duration of 2 years. All the acute poisoning cases admitted in the ICU were studied for epidemiological profiles, poisoning characteristics, and various clinical factors affecting the outcome of the patients.Results:Eighty-five patients with acute poisoning were included in the study. Suicidal attempt leading to acute poisoning was seen in majority of the young population. Majority of the poisoning was due to the organophosphorous compounds (43.5%). Patients with organophosphorous poisoning had a significantly longer duration of ICU stay (P = 0.020). The survival of the patients was significantly affected by age, duration of presentation to the hospital, Glasgow Coma Scale, Sequential Organ Failure Assessment score, need for mechanical ventilation, duration of ICU stay, hepatic failure, coagulopathy, and need for vasoactive drugs (P < 0.05). The independent predictors of mortality observed in the study were age, delayed presentation to the hospital, hepatic failure, and need for mechanical ventilation.Conclusion:Organophosphorous poisoning was the most common acute poisoning in young population leading to the ICU admission. Older age, delayed initiation of the resuscitative measures, need for mechanical ventilation, and hepatic failure significantly affected the mortality.

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Section: Introductionmentioning

confidence: 99%

Clinical profile and outcome of patients with acute poisoning admitted in intensive care unit of tertiary care center in Eastern Nepal

Rajbanshi¹,

Arjyal²,

Mandal³

2018

Indian Journal of Critical Care Medicine

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“…Shabestari et al, reported the least time of hospitalization for poisoning as one day and the maximum was 4 days [20]. While in the study of Dhakal et al, the time of hospitalization in the majority of cases was reported as less than 24 hours [28]. Since most cases of poisoning, accidents had occurred in the home and the kitchen and in the evening and night.…”

Section: Discussionmentioning

confidence: 99%

Poisoning and its Related Factors in Children under 6 Years Old in Rasht

Shirdelpour

Shafipour

Mohammad

et al. 2017

J Holist Nurs Midwifery

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Introduction: Poisoning is a major public health problem and one of the most common causes of child mortality, particularly in developing countries. Incidences of poisoning are variable according to the cultural and economic characteristics of particular communities. Objective: The purpose of this study was to analyze cases of poisoning in children under 6 years of age underwent hospitalization in a health center of Rasht. Materials and Methods: This study was conducted as a case-control study. The study included 2160 cases of hospitalized children under 6 years old. The study duration was 4 months. There were 2 groups, 70 children hospitalized because of poisoning (case group) and a control group of 105 people (1.5 times that of the case group) that consisted of children under 6 years of age and , non-hospitalized. Information gathered by questionnaire included; demographic information on individuals and families, as well as method of poisoning and the child's condition after hospitalization. Information was collected from interviews and medical records. Data were analyzed after collection using descriptive statistics (frequency distribution, means and standard deviation) and inferential statistics (chi-square tests, t-test). Results: The findings showed that most children (51.4 %) were between the ages of 1-3 years. Of the total sample 64.3 % were boys and 35.7 % were girls. In 80% of cases, poisoning was accidental and 97.1% were gastrointestinal in nature. In 51.4% cases, the cause was poisoning from medicine; 36.1% of cases were caused by methadone and in 17.1% of cases incidents had occurred in the kitchen. There was significant difference in both case and control groups in terms of father's level of education (P = 0.012) and mother's job (P = 0.025). Conclusion: Results showed that the most common cause of poisoning in children aged 1-3 was from pharmaceutical drugs; determined by the side effects of poisoning. A low rate of parental awareness was considered to have contributed to these cases of poisoning so parental awareness was determined as significantly important for improving childcare in the study region.

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“…5,6 Studies from Nepal have reported prescription medication and organophosphorus (OP) poisoning as the most common agents. 7,8 Although most cases of childhood poisoning are non-lethal, the consequences of some childhood poisoning extend far beyond immediate harm with long-term health complications. 9 The clinical severity depends upon various factors and more studies are required to recognize poisoning trends for developing targeted prevention strategies, improving medical interventions, and reducing the incidence and severity.…”

Section: Introductionmentioning

confidence: 99%

Acute Poisoning among Children Admitted in a Tertiary Care Hospital: A Descriptive Cross-sectional Study

Aryal,

Karki,

Lamichhane

2024

J Nepal Med Assoc

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Introduction: Acute poisoning is one of the critical causes of hospital admission in children worldwide. Understanding the clinico-demographic profile of childhood poisoning will help in developing targeted prevention strategies. This study aimed to find the prevalence of acute poisoning cases among children admitted to a tertiary care hospital.Methods: A descriptive cross-sectional study was done among 4972 children admitted in the pediatric ward, High Dependency Care Unit, and Pediatric Intensive Care Unit of a tertiary care hospital in Nepal. The data were collected from the hospital records from over three years between 1 January 2020 and 31 December 2022 after receiving ethical approval from the Institutional Review Committee. A convenience sampling method was used. Data related to the clinical and demographic data were collected from the patients with acute poisoning and analyzed. Point estimate at 95% Confidence Interval was calculated.Results: Out of 4972 paediatric cases admitted to the hospital, acute poisoning was seen in 57 (1.14%) (0.81-1.39, 95% Confidence Interval) patients. Out of these acute poisoning cases, 31 (54.39%) were accidental. The mean age was 10.10±5.40 years with 35 (61.40%) patients from the adolescent age group. Conclusions: This study conducted in a Nepalese tertiary care hospital identifies acute poisoning as a notable concern among pediatric admissions.

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Clinical Profile of Acute Poisoning in Children at a Teaching Hospital in Lalitpur

Cited by 10 publications

References 6 publications

Clinical profile and outcome of patients with acute poisoning admitted in intensive care unit of tertiary care center in Eastern Nepal

Clinical profile and outcome of patients with acute poisoning admitted in intensive care unit of tertiary care center in Eastern Nepal

Poisoning and its Related Factors in Children under 6 Years Old in Rasht

Acute Poisoning among Children Admitted in a Tertiary Care Hospital: A Descriptive Cross-sectional Study

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