Objectives
Little is known about the ongoing mortality risk and healthcare utilization among U.S. children after discharge from a hospitalization involving ICU care. We sought to understand risks for hospital readmission and trends in mortality during the year following ICU discharge.
Design
We performed a retrospective observational cohort study using administrative claims data from the years 2006–2013 obtained from the Truven Health Analytics MarketScan® Database.
Subjects
We included all children in the dataset admitted to a U.S. ICU ≤18 years old.
Interventions
The primary outcome was non-elective readmission in the year following discharge. Risk of rehospitalization was determined using a Cox proportional hazards model.
Measurements and Main Results
We identified 109,130 children with at least one ICU admission in the dataset. Over three-quarters of the index ICU admissions (78.6%) had an ICU length of stay ≤ 3 days and the overall index hospitalization mortality rate was 1.4%. In multivariate analysis, risk of non-elective readmission for children without cancer was higher with longer index ICU admission LOS, younger age, and several chronic and acute conditions. By the end of the one year observation period, 36.0% of children with an index ICU LOS ≥ 14 days had been readmitted, compared to only 13.9% of children who had an index ICU LOS = 1 day. Mortality in the year after ICU discharge was low overall (106 deaths per 10,000 person-years of observation), but was highest among children with an initial index ICU admission LOS ≥ 14 days (599 deaths per 10,000 person-years).
Conclusions
Readmission after ICU care is common. Further research is needed to investigate the potentially modifiable factors affecting likelihood of readmissions after discharge from the ICU. While late mortality was relatively uncommon overall, it was ten-fold higher in the year after ICU discharge than in the general U.S. pediatric population.