Clinical Profile of End Stage Renal Disease Patients Undergoing Hemodialysis in a Tertiary Hospital of Lumbini Province, Nepal

Abstract

Background: Data regarding the clinical profile of end-stage renal disease (ESRD) and dialysis in Mid western Nepal are scarce and knowledge about the spectrum of renal disease is very limited. This study was about the clinical profile of patients with ESRD in a tertiary hospital of Lumbini province of Nepal. Materials and Methods: This was a retrospective, observational study carried out in a dialysis unit in a tertiary hospital. Forty patients who were on maintenance haemodialysis on regular a basis in the hospital for at least 3 months were selected for the study. Patients demographic, clinical data and laboratory parameters were recorded in preformed performa. Data were entered into Statistical Package for the Social Sciences 21 and descriptive analysis was done. Results: Most of the patients were in the age group 20 to 60 years 33(82.5%). Male: female ratio of 1.6:1. Most common cause for end stage renal disease was hypertension followed by diabetes. Anaemia, hypocalcaemia and hyponatremia were found to be the common complications associated with the patients. Conclusion: Early diagnosis and treatment of hypertension and diabetes may be the key to decrease the incidence of chronic kidney disease patients and also halt the progression to End stage renal disease. Key words: Chronic kidney disease, haemodialysis, end stage renal disease

Prevalence and Factors Associated With Chronic Kidney Disease in Selected Hospitals in Kigali, Rwanda

“…The findings of this study showed that diabetes was 11 times and hypertension was 6 times significantly associated with chronic kidney disease which was also supported by other studies but with low Adjusted Odd ratios. This showed that hypertension and diabetes AORs were 2.4, 95% CI 2.0 to 3.0), diabetes mellitus (AOR 3.2, 95% CI 2.5 to 4.1), p<0.05, [14]. The astonishing results and the difference in this study's high AOR levels may be justified by the study settings of both studies where the Nepal study was carried out on a nationally representative sample while this study was limited to inpatients.…”